{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T15:11:19Z","timestamp":1772118679496,"version":"3.50.1"},"reference-count":54,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2020,12,1]],"date-time":"2020-12-01T00:00:00Z","timestamp":1606780800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"},{"start":{"date-parts":[[2021,4,14]],"date-time":"2021-04-14T00:00:00Z","timestamp":1618358400000},"content-version":"vor","delay-in-days":134,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["asbmr.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2020,12,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>The development of coronavirus disease 2019 (COVID-19) vaccines has proceeded at an unprecedented pace, with numerous trials conducted simultaneously across the world as a result of massive technological and financial resource expenditures. With multiple vaccines having now received regulatory approval, public health efforts to promote widespread vaccine dissemination are currently underway. There has been particular emphasis placed on vaccination of older populations, the age group in which COVID-19 infection has been most lethal. However, such widespread vaccination approaches have necessarily raised important questions related to potential interactions with underlying diseases and concomitant treatments among persons to be vaccinated. Osteoporosis is a chronic condition marked by reduced bone strength and an associated increased risk for fracture that generally requires sustained medical intervention(s). Osteoporosis is neither associated with a higher risk of COVID-19 infection nor by more pronounced disease severity following infection, such that individuals with osteoporosis need not be more highly prioritized for COVID-19 vaccination. Osteoporosis therapies do not interfere with the efficacy or side effect profiles of COVID-19 vaccines and should not be stopped or indefinitely delayed because of vaccination. Depending on the specific drug profile within an anti-osteoporosis medication category, minor adjustments to the timing of drug administration may be considered with respect to the patient's COVID-19 vaccination schedule. Herein we provide practical recommendations for the care of patients requiring treatment for osteoporosis in the setting of COVID-19 vaccination. \u00a9 2021 American Society for Bone and Mineral Research (ASBMR).<\/jats:p>","DOI":"10.1002\/jbmr.4304","type":"journal-article","created":{"date-parts":[[2021,4,8]],"date-time":"2021-04-08T17:56:21Z","timestamp":1617904581000},"page":"1042-1047","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Vaccination for Coronavirus Disease 2019 (COVID-19) and Relationship to Osteoporosis Care: Current Evidence and Suggested Approaches"],"prefix":"10.1093","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9582-1906","authenticated-orcid":false,"given":"Elena","family":"Tsourdi","sequence":"first","affiliation":[{"name":"Center for Healthy Aging Universit\u00e4tsklinikum Dresden Dresden Germany"},{"name":"Department of Medicine III Universit\u00e4tsklinikum Dresden Dresden Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0633-0839","authenticated-orcid":false,"given":"Elaine W.","family":"Yu","sequence":"additional","affiliation":[{"name":"Endocrine Unit Massachusetts General Hospital\/Harvard Medical School Boston MA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9386-7732","authenticated-orcid":false,"given":"Suzanne M.","family":"Jan de Beur","sequence":"additional","affiliation":[{"name":"Division of Endocrinology, Diabetes and Metabolism Johns Hopkins University School of Medicine Baltimore MD USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3662-7345","authenticated-orcid":false,"given":"Matthew T.","family":"Drake","sequence":"additional","affiliation":[{"name":"Robert and Arlene Kogod Center on Aging Mayo Clinic Rochester MN USA"},{"name":"Division of Endocrinology, Diabetes, Metabolism and Nutrition Mayo Clinic Rochester MN USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2021,4,8]]},"reference":[{"issue":"5","key":"2024012713483013800_jbmr4304-bib-0001","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1016\/S1473-3099(20)30120-1","article-title":"An interactive web-based dashboard to track COVID-19 in real time","volume":"20","author":"Dong","year":"2020","journal-title":"Lancet Infect Dis"},{"issue":"24","key":"2024012713483013800_jbmr4304-bib-0002","doi-asserted-by":"crossref","first-page":"2368","DOI":"10.1056\/NEJMms2009984","article-title":"The untold toll\u2014the pandemic's effect on patients without Covid-19","volume":"382","author":"Rosenbaum","year":"2020","journal-title":"N Engl J Med"},{"issue":"6","key":"2024012713483013800_jbmr4304-bib-0003","doi-asserted-by":"crossref","first-page":"1547","DOI":"10.1007\/s11357-020-00272-3","article-title":"Sarcopenia during COVID-19 lockdown restrictions: long-term health effects of short-term muscle loss","volume":"42","author":"Kirwan","year":"2020","journal-title":"Geroscience"},{"issue":"10","key":"2024012713483013800_jbmr4304-bib-0004","doi-asserted-by":"crossref","first-page":"2083","DOI":"10.1002\/jbmr.4113","article-title":"Osteoporotic fractures in the time of COVID-19","volume":"35","author":"Bhattacharyya","year":"2020","journal-title":"J Bone Miner Res"},{"issue":"21","key":"2024012713483013800_jbmr4304-bib-0005","doi-asserted-by":"crossref","first-page":"7732","DOI":"10.3390\/ijerph17217732","article-title":"State of fragility fractures management during the COVID-19 pandemic","volume":"17","author":"Tarantino","year":"2020","journal-title":"Int J Environ Res Public Health"},{"issue":"6","key":"2024012713483013800_jbmr4304-bib-0006","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.1002\/jbmr.4049","article-title":"Osteoporosis management in the era of COVID-19","volume":"35","author":"Yu","year":"2020","journal-title":"J Bone Miner Res"},{"issue":"9","key":"2024012713483013800_jbmr4304-bib-0007","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1038\/s41574-020-0379-z","article-title":"Managing fragility fractures during the COVID-19 pandemic","volume":"16","author":"Napoli","year":"2020","journal-title":"Nat Rev Endocrinol"},{"issue":"5","key":"2024012713483013800_jbmr4304-bib-0008","doi-asserted-by":"crossref","first-page":"R133","DOI":"10.1530\/EJE-20-0665","article-title":"Mechanisms in endocrinology: vitamin D and COVID-19","volume":"183","author":"Bilezikian","year":"2020","journal-title":"Eur J Endocrinol"},{"issue":"20","key":"2024012713483013800_jbmr4304-bib-0009","doi-asserted-by":"crossref","first-page":"1986","DOI":"10.1056\/NEJMe2025111","article-title":"The Covid-19 vaccine-development multiverse","volume":"383","author":"Heaton","year":"2020","journal-title":"N Engl J Med"},{"key":"2024012713483013800_jbmr4304-bib-0010","doi-asserted-by":"crossref","first-page":"198114","DOI":"10.1016\/j.virusres.2020.198114","article-title":"COVID-19 vaccine: a comprehensive status report","volume":"288","author":"Kaur","year":"2020","journal-title":"Virus Res"},{"issue":"10240","key":"2024012713483013800_jbmr4304-bib-0011","doi-asserted-by":"crossref","first-page":"1845","DOI":"10.1016\/S0140-6736(20)31208-3","article-title":"Safety, tolerability, and immunogenicity of a recombinant adenovirus type-5 vectored COVID-19 vaccine: a dose-escalation, open-label, non-randomised, first-in-human trial","volume":"395","author":"Zhu","year":"2020","journal-title":"Lancet"},{"issue":"5","key":"2024012713483013800_jbmr4304-bib-0012","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1056\/NEJMoa2035389","article-title":"Efficacy and safety of the mRNA-1273 SARS-CoV-2 vaccine","volume":"384","author":"Baden","year":"2021","journal-title":"N Engl J Med"},{"issue":"10264","key":"2024012713483013800_jbmr4304-bib-0013","doi-asserted-by":"crossref","first-page":"1732","DOI":"10.1016\/S0140-6736(20)32224-8","article-title":"Who should be prioritised for COVID-19 vaccines?","volume":"396","author":"Hassan-Smith","year":"2020","journal-title":"Lancet"},{"issue":"6","key":"2024012713483013800_jbmr4304-bib-0014","doi-asserted-by":"crossref","first-page":"eabf1374","DOI":"10.1126\/sciadv.abf1374","article-title":"Vaccine optimization for COVID-19: who to vaccinate first?","volume":"7","author":"Matrajt","year":"2021","journal-title":"Sci Adv"},{"issue":"2","key":"2024012713483013800_jbmr4304-bib-0015","doi-asserted-by":"crossref","first-page":"e602","DOI":"10.1210\/clinem\/dgaa738","article-title":"Radiological thoracic vertebral fractures are highly prevalent in COVID-19 and predict disease outcomes","volume":"106","author":"di Filippo","year":"2021","journal-title":"J Clin Endocrinol Metab"},{"key":"2024012713483013800_jbmr4304-bib-0016","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1007\/978-981-13-3681-2_16","article-title":"Osteoporosis and the ageing skeleton","volume":"91","author":"Aspray","year":"2019","journal-title":"Subcell Biochem"},{"issue":"2","key":"2024012713483013800_jbmr4304-bib-0017","doi-asserted-by":"crossref","first-page":"e16","DOI":"10.1016\/j.jinf.2020.04.021","article-title":"Risk factors of critical & mortal COVID-19 cases: a systematic literature review and meta-analysis","volume":"81","author":"Zheng","year":"2020","journal-title":"J Infect"},{"issue":"7","key":"2024012713483013800_jbmr4304-bib-0018","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1016\/S2213-8587(20)30183-2","article-title":"Vitamin-D and COVID-19: do deficient risk a poorer outcome?","volume":"8","author":"Mitchell","year":"2020","journal-title":"Lancet Diabetes Endocrinol"},{"issue":"8","key":"2024012713483013800_jbmr4304-bib-0019","doi-asserted-by":"crossref","first-page":"1804","DOI":"10.1016\/j.mayocp.2020.05.036","article-title":"Vitamin D supplementation during the COVID-19 pandemic","volume":"95","author":"Siuka","year":"2020","journal-title":"Mayo Clin Proc"},{"issue":"11","key":"2024012713483013800_jbmr4304-bib-0020","doi-asserted-by":"crossref","first-page":"3361","DOI":"10.3390\/nu12113361","article-title":"Evidence regarding vitamin D and risk of COVID-19 and its severity","volume":"12","author":"Mercola","year":"2020","journal-title":"Nutrients"},{"issue":"1","key":"2024012713483013800_jbmr4304-bib-0021","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1159\/000508951","article-title":"Covid-19 and exercise-induced immunomodulation","volume":"27","author":"Leandro","year":"2020","journal-title":"Neuroimmunomodulation"},{"issue":"8","key":"2024012713483013800_jbmr4304-bib-0022","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1017\/S0007114520003311","article-title":"Nutritional status, diet and viral respiratory infections: perspectives for severe acute respiratory syndrome coronavirus 2","volume":"125","author":"Morais","year":"2021","journal-title":"Br J Nutr"},{"issue":"8","key":"2024012713483013800_jbmr4304-bib-0023","doi-asserted-by":"crossref","first-page":"1698","DOI":"10.1016\/j.injury.2020.06.022","article-title":"Epidemiologic characteristics of traumatic fractures during the outbreak of coronavirus disease 2019 (COVID-19) in China: a retrospective & comparative multi-center study","volume":"51","author":"Lv","year":"2020","journal-title":"Injury"},{"issue":"7","key":"2024012713483013800_jbmr4304-bib-0024","doi-asserted-by":"crossref","first-page":"1414","DOI":"10.1016\/j.injury.2020.05.016","article-title":"Impact of the COVID-19 pandemic on an emergency traumatology service: experience at a tertiary trauma centre in Spain","volume":"51","author":"Nu\u00f1ez","year":"2020","journal-title":"Injury"},{"key":"2024012713483013800_jbmr4304-bib-0025","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/j.bone.2013.10.017","article-title":"Efficacy, tolerability and safety of once-monthly administration of 75mg risedronate in Japanese patients with involutional osteoporosis: a comparison with a 2.5mg once-daily dosage regimen","volume":"59","author":"Hagino","year":"2014","journal-title":"Bone"},{"issue":"5","key":"2024012713483013800_jbmr4304-bib-0026","doi-asserted-by":"crossref","first-page":"1238","DOI":"10.1016\/j.bone.2007.01.016","article-title":"A single zoledronic acid infusion reduces bone resorption markers more rapidly than weekly oral alendronate in postmenopausal women with low bone mineral density","volume":"40","author":"Saag","year":"2007","journal-title":"Bone"},{"issue":"1","key":"2024012713483013800_jbmr4304-bib-0027","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1002\/jbmr.521","article-title":"Circulating \u03b3\u03b4 T cells and the risk of acute-phase response after zoledronic acid administration","volume":"27","author":"Rossini","year":"2012","journal-title":"J Bone Miner Res"},{"issue":"9","key":"2024012713483013800_jbmr4304-bib-0028","doi-asserted-by":"crossref","first-page":"4380","DOI":"10.1210\/jc.2010-0597","article-title":"Characterization of and risk factors for the acute-phase response after zoledronic acid","volume":"95","author":"Reid","year":"2010","journal-title":"J Clin Endocrinol Metab"},{"key":"2024012713483013800_jbmr4304-bib-0029"},{"issue":"2","key":"2024012713483013800_jbmr4304-bib-0030","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1002\/jbmr.1494","article-title":"The effect of 3 versus 6\u2009years of zoledronic acid treatment of osteoporosis: a randomized extension to the HORIZON-Pivotal Fracture Trial (PFT)","volume":"27","author":"Black","year":"2012","journal-title":"J Bone Miner Res"},{"issue":"5","key":"2024012713483013800_jbmr4304-bib-0031","doi-asserted-by":"crossref","first-page":"934","DOI":"10.1002\/jbmr.2442","article-title":"The effect of 6 versus 9\u2009years of zoledronic acid treatment in osteoporosis: a randomized second extension to the HORIZON-Pivotal Fracture Trial (PFT)","volume":"30","author":"Black","year":"2015","journal-title":"J Bone Miner Res"},{"issue":"25","key":"2024012713483013800_jbmr4304-bib-0032","doi-asserted-by":"crossref","first-page":"2407","DOI":"10.1056\/NEJMoa1808082","article-title":"Fracture prevention with zoledronate in older women with osteopenia","volume":"379","author":"Reid","year":"2018","journal-title":"N Engl J Med"},{"issue":"6","key":"2024012713483013800_jbmr4304-bib-0033","doi-asserted-by":"crossref","first-page":"1389","DOI":"10.1016\/j.bone.2012.03.016","article-title":"Five years of anti-resorptive activity after a single dose of zoledronate\u2014results from a randomized double-blind placebo-controlled trial","volume":"50","author":"Grey","year":"2012","journal-title":"Bone"},{"issue":"4","key":"2024012713483013800_jbmr4304-bib-0034","doi-asserted-by":"crossref","first-page":"dgaa062","DOI":"10.1210\/clinem\/dgaa062","article-title":"Ten years of very infrequent zoledronate therapy in older women: an open-label extension of a randomized trial","volume":"105","author":"Grey","year":"2020","journal-title":"J Clin Endocrinol Metab"},{"key":"2024012713483013800_jbmr4304-bib-0035","doi-asserted-by":"crossref","first-page":"629","DOI":"10.3389\/fimmu.2019.00629","article-title":"The RANKL-RANK axis: a bone to thymus round trip","volume":"10","author":"Sobacchi","year":"2019","journal-title":"Front Immunol"},{"key":"2024012713483013800_jbmr4304-bib-0036","doi-asserted-by":"crossref","first-page":"630","DOI":"10.1038\/s41586-020-03041-6","article-title":"Correlates of protection against SARS-CoV-2 in rhesus macaques","volume":"590","author":"McMahan","year":"2021","journal-title":"Nature"},{"issue":"20","key":"2024012713483013800_jbmr4304-bib-0037","doi-asserted-by":"crossref","first-page":"19923","DOI":"10.18632\/aging.104117","article-title":"Influence of anti-osteoporosis treatments on the incidence of COVID-19 in patients with non-inflammatory rheumatic conditions","volume":"12","author":"Blanch-Rubi\u00f3","year":"2020","journal-title":"Aging (Albany NY)"},{"issue":"7","key":"2024012713483013800_jbmr4304-bib-0038","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1016\/S2213-8587(17)30138-9","article-title":"10\u2009years of denosumab treatment in postmenopausal women with osteoporosis: results from the phase 3 randomised FREEDOM trial and open-label extension","volume":"5","author":"Bone","year":"2017","journal-title":"Lancet Diabetes Endocrinol"},{"key":"2024012713483013800_jbmr4304-bib-0039"},{"key":"2024012713483013800_jbmr4304-bib-0040","doi-asserted-by":"crossref","first-page":"1174","DOI":"10.1002\/art.40874","article-title":"Denosumab versus risedronate in glucocorticoid-induced osteoporosis: final results of a twenty-four month randomized, double-blind, double-dummy trial","volume":"71","author":"Saag","year":"2019","journal-title":"Arthritis Rheumatol"},{"key":"2024012713483013800_jbmr4304-bib-0041","doi-asserted-by":"crossref","first-page":"1456","DOI":"10.1002\/art.39075","article-title":"Risk of hospitalized infection among rheumatoid arthritis patients concurrently treated with a biologic agent and denosumab","volume":"67","author":"Curtis","year":"2015","journal-title":"Arthritis Rheumatol"},{"issue":"2","key":"2024012713483013800_jbmr4304-bib-0042","doi-asserted-by":"crossref","first-page":"170","DOI":"10.3899\/jrheum.161270","article-title":"Occurrence of serious infection in patients with rheumatoid arthritis treated with biologics and denosumab observed in a clinical setting","volume":"45","author":"Lau","year":"2018","journal-title":"J Rheumatol"},{"issue":"1","key":"2024012713483013800_jbmr4304-bib-0043","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/S1470-2045(19)30687-4","article-title":"Adjuvant denosumab in early breast cancer (D-CARE): an international, multicentre, randomised, controlled, phase 3 trial","volume":"21","author":"Coleman","year":"2020","journal-title":"Lancet Oncol"},{"issue":"1","key":"2024012713483013800_jbmr4304-bib-0044","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1007\/s00520-015-2904-5","article-title":"Safety of long-term denosumab therapy: results from the open label extension phase of two phase 3 studies in patients with metastatic breast and prostate cancer","volume":"24","author":"Stopeck","year":"2016","journal-title":"Support Care Cancer"},{"issue":"5","key":"2024012713483013800_jbmr4304-bib-0045","article-title":"Risk for infections during treatment with denosumab for osteoporosis: a systematic review and meta-analysis","volume":"105","author":"Dirk-Cohen","year":"2020","journal-title":"J Clin Endocrinol Metab"},{"key":"2024012713483013800_jbmr4304-bib-0046","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1210\/clinem\/dgaa756","article-title":"Fracture risk and management of discontinuation of denosumab therapy: a systematic review and position statement by ECTS","volume":"106","author":"Tsourdi","year":"2021","journal-title":"J Clin Endocrinol Metab"},{"issue":"1","key":"2024012713483013800_jbmr4304-bib-0047","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1007\/s10549-019-05458-8","article-title":"Sixty spontaneous vertebral fractures after denosumab discontinuation in 15 women with early-stage breast cancer under aromatase inhibitors","volume":"179","author":"Gonzalez-Rodriguez","year":"2020","journal-title":"Breast Cancer Res Treat"},{"issue":"8","key":"2024012713483013800_jbmr4304-bib-0048","doi-asserted-by":"crossref","first-page":"2915","DOI":"10.1210\/jc.2008-2630","article-title":"Effects of teriparatide treatment and discontinuation in postmenopausal women and eugonadal men with osteoporosis","volume":"94","author":"Leder","year":"2009","journal-title":"J Clin Endocrinol Metab"},{"issue":"8","key":"2024012713483013800_jbmr4304-bib-0049","doi-asserted-by":"crossref","first-page":"1397","DOI":"10.1002\/jbmr.3452","article-title":"Effects of 24 months of treatment with romosozumab followed by 12 months of denosumab or placebo in postmenopausal women with low bone mineral density: a randomized, double-blind, phase 2, parallel groups study","volume":"33","author":"McClung","year":"2018","journal-title":"J Bone Miner Res"},{"issue":"1","key":"2024012713483013800_jbmr4304-bib-0050","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1016\/j.bbrc.2012.06.100","article-title":"TNF-\u03b1 mediates the stimulation of sclerostin expression in an estrogen-deficient condition","volume":"424","author":"Kim","year":"2012","journal-title":"Biochem Biophys Res Commun"},{"issue":"8","key":"2024012713483013800_jbmr4304-bib-0051","doi-asserted-by":"crossref","first-page":"1434","DOI":"10.1359\/jbmr.090305","article-title":"Pro-inflammatory cytokines TNF-related weak inducer of apoptosis (TWEAK) and TNFalpha induce the mitogen-activated protein kinase (MAPK)-dependent expression of sclerostin in human osteoblasts","volume":"24","author":"Vincent","year":"2009","journal-title":"J Bone Miner Res"},{"issue":"11","key":"2024012713483013800_jbmr4304-bib-0052","doi-asserted-by":"crossref","first-page":"3261","DOI":"10.1007\/s10067-020-04948-1","article-title":"Efficacy and safety of romosozumab in treatment for low bone mineral density: a systematic review and meta-analysis","volume":"39","author":"Kaveh","year":"2020","journal-title":"Clin Rheumatol"},{"issue":"5","key":"2024012713483013800_jbmr4304-bib-0053","doi-asserted-by":"crossref","first-page":"3027","DOI":"10.21873\/invivo.12135","article-title":"Raloxifene and bazedoxifene could be promising candidates for preventing the COVID-19 related cytokine storm, ARDS and mortality","volume":"34","author":"Smetana","year":"2020","journal-title":"In Vivo"},{"issue":"2","key":"2024012713483013800_jbmr4304-bib-0054","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1007\/s12275-021-0617-7","article-title":"Raloxifene as a treatment option for viral infections","volume":"59","author":"Hong","year":"2021","journal-title":"J Microbiol"}],"container-title":["Journal of Bone and Mineral Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jbmr.4304","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/jbmr.4304","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/academic.oup.com\/jbmr\/article-pdf\/36\/6\/1042\/55457007\/jbmr4304.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jbmr\/article-pdf\/36\/6\/1042\/55457007\/jbmr4304.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,3,13]],"date-time":"2024-03-13T11:07:06Z","timestamp":1710328026000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jbmr\/article\/36\/6\/1042-1047\/7516637"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,12,1]]},"references-count":54,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2021,4,8]]},"published-print":{"date-parts":[[2020,12,1]]}},"URL":"https:\/\/doi.org\/10.1002\/jbmr.4304","relation":{"has-review":[{"id-type":"doi","id":"10.1002\/JBMR.4304\/v1\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/JBMR.4304\/v1\/review2","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/JBMR.4304\/v1\/review1","asserted-by":"object"}]},"ISSN":["0884-0431","1523-4681"],"issn-type":[{"value":"0884-0431","type":"print"},{"value":"1523-4681","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2020,12,1]]},"published":{"date-parts":[[2020,12,1]]},"assertion":[{"value":"2021-03-08","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-03-30","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-04-14","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}