{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T10:21:12Z","timestamp":1791973272275,"version":"4.3.4"},"reference-count":42,"publisher":"Oxford University Press (OUP)","issue":"8","license":[{"start":{"date-parts":[[1996,8,1]],"date-time":"1996-08-01T00:00:00Z","timestamp":838857600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1996,8,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>The purpose of this study was to evaluate the usefulness in osteoporosis of a new ultrasound imaging device able to create a parametric image of broadband ultrasound attenuation (BUA) at the os calcis. Three regions of interest were located in the great tuberosity of the os calcis. Precision was evaluated in 37 patients. Calcaneal bone mineral density (BMD) and BUA were compared in 33 patients. In 236 patients (including 77 with osteoporotic fractures), BUA and lumbar and femoral BMD measurements were performed. The measurements were compared using correlation coefficients. Their clinical value was estimated by comparisons of the results between patients with fractures and age-matched controls, using comparisons of the means, areas under the ROC curves, and logistic regression. Precision was in a 1.4-3.3% range. Local BUA and BMD were highly correlated (r = 0.88). Significant correlations were found between BUA and lumbar (r = 0.56) and femur (r = 0.66) BMD. In multiple regression, years since menopause and weight were significant predictors of BUA. Patients with fractures had lower BUA and BMD than age-matched controls. BUA showed the largest difference between the two populations (13-16%). Areas under the ROC curves were similar for BUA and BMD. Logistic regression after adjustment for confounding factors showed that BUA discriminated between fracture and nonfracture subjects. Broadband ultrasound attenuation imaging improves the reproducibility of ultrasound measurements. It may be useful in osteoporosis, due to its good discriminating value.<\/jats:p>","DOI":"10.1002\/jbmr.5650110810","type":"journal-article","created":{"date-parts":[[2010,2,3]],"date-time":"2010-02-03T15:37:04Z","timestamp":1265211424000},"page":"1112-1118","source":"Crossref","is-referenced-by-count":63,"title":["Broadband ultrasound attenuation imaging: A new imaging method in osteoporosis"],"prefix":"10.1093","volume":"11","author":[{"given":"Christian","family":"Roux","sequence":"first","affiliation":[{"name":"Centre d'Evaluation des Maladies Osseuses, Hopital Cochin, Universit\u00e9 Ren\u00e9 Descartes, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruno","family":"Fournier","sequence":"additional","affiliation":[{"name":"Laboratoire d'Imagerie Param\u00e9trique, URA CNRS 1458, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pascal","family":"Laugier","sequence":"additional","affiliation":[{"name":"Laboratoire d'Imagerie Param\u00e9trique, URA CNRS 1458, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christine","family":"Chappard","sequence":"additional","affiliation":[{"name":"Centre d'Evaluation des Maladies Osseuses, Hopital Cochin, Universit\u00e9 Ren\u00e9 Descartes, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sami","family":"Kolta","sequence":"additional","affiliation":[{"name":"Centre d'Evaluation des Maladies Osseuses, Hopital Cochin, Universit\u00e9 Ren\u00e9 Descartes, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maxime","family":"Dougados","sequence":"additional","affiliation":[{"name":"Centre d'Evaluation des Maladies Osseuses, Hopital Cochin, Universit\u00e9 Ren\u00e9 Descartes, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Genevi\u00e8ve","family":"Berger","sequence":"additional","affiliation":[{"name":"Laboratoire d'Imagerie Param\u00e9trique, URA CNRS 1458, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[1996,8,1]]},"reference":[{"key":"2024013114244452400_bib1","doi-asserted-by":"crossref","first-page":"646","DOI":"10.1016\/0002-9343(93)90218-E","article-title":"Diagnosis, prophylaxis and treatment of osteoporosis","volume":"94","author":"Consensus development conference","year":"1993","journal-title":"Am J Med"},{"key":"2024013114244452400_bib2","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/0140-6736(93)92555-8","article-title":"Bone density at various sites for prediction of hip fracture","volume":"341","author":"Cummings","year":"1992","journal-title":"Lancet"},{"key":"2024013114244452400_bib3","doi-asserted-by":"crossref","first-page":"1227","DOI":"10.1002\/jbmr.5650081010","article-title":"Long-term fracture prediction by bone mineral assessed at different skeletal sites","volume":"8","author":"Melton","year":"1993","journal-title":"J Bone Miner Res"},{"key":"2024013114244452400_bib4","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1016\/0002-9378(85)90338-2","article-title":"Prediction of post menopausal fracture risk with use of bone mineral measurements","volume":"153","author":"Wasnich","year":"1985","journal-title":"Am J Obstet Gynecol"},{"key":"2024013114244452400_bib5","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1243\/EMED_JOUR_1984_013_022_02","article-title":"The measurement of broadband ultrasonic attenuation in cancellous bone","volume":"13","author":"Langton","year":"1984","journal-title":"Eng Med"},{"key":"2024013114244452400_bib6","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1002\/jbmr.5650080502","article-title":"Perspectives: Ultrasound assessment of bone","volume":"8","author":"Kaufman","year":"1993","journal-title":"J Bone Miner Res"},{"key":"2024013114244452400_bib7","doi-asserted-by":"crossref","first-page":"1331","DOI":"10.1088\/0031-9155\/36\/10\/003","article-title":"The interaction of ultrasound with cancellous bone","volume":"36","author":"McKelvie","year":"1991","journal-title":"Physical Med Biol"},{"key":"2024013114244452400_bib8","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1016\/0041-624X(92)90095-4","article-title":"The effect of bone structure on ultrasonic attenuation and velocity","volume":"30","author":"Tavakoli","year":"1992","journal-title":"Ultrasonics"},{"key":"2024013114244452400_bib9","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1007\/BF00310168","article-title":"Three quantitative ultrasound parameters reflect bone structure","volume":"55","author":"Gl\u00fcer","year":"1994","journal-title":"Calcif Tissue Int"},{"key":"2024013114244452400_bib10","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1007\/BF01623382","article-title":"Screening for osteoporosis: Comparison between dual energy X-ray absorptiometry and broadband ultrasound attenuation in 1000 perimenopausal women","volume":"3","author":"Massie","year":"1993","journal-title":"Osteoporosis Int"},{"key":"2024013114244452400_bib11","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1007\/BF00308316","article-title":"Spine and femur density and broadband ultrasound attenuation of the calcaneus in normal Spanish women","volume":"52","author":"Palacios","year":"1993","journal-title":"Calcif Tissue Int"},{"key":"2024013114244452400_bib12","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1007\/BF01623828","article-title":"Ultrasound measurements on os calcis: Precision and age-related changes in a normale female population","volume":"3","author":"Schott","year":"1993","journal-title":"Osteoporosis Int"},{"key":"2024013114244452400_bib13","first-page":"771","article-title":"Broadband ultrasound attenuation of the os calcaneus and bone density measurements","volume":"60","author":"Roux","year":"1993","journal-title":"Rev Rhum"},{"key":"2024013114244452400_bib14","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1007\/BF00334324","article-title":"Broadband ultrasound attenuation and dual energy X-ray absorptiometry in patients with hip fractures: Which technique discriminates fracture risk","volume":"54","author":"Stewart","year":"1994","journal-title":"Calcif Tissue Int"},{"key":"2024013114244452400_bib15","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1148\/radiology.194.1.7997586","article-title":"Broadband ultrasound attenuation in the diagnosis of osteoporosis: Correlation with ostcodensitometry and fracture","volume":"194","author":"Funke","year":"1995","journal-title":"Radiology"},{"key":"2024013114244452400_bib16","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1002\/jbmr.5650100210","article-title":"Ultrasound discriminates patients with hip fracture equally well as dual energy X-ray absorptiometry and independently of bone mineral density","volume":"10","author":"Schott","year":"1995","journal-title":"J Bone Miner Res"},{"key":"2024013114244452400_bib17","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1002\/jbmr.5650100304","article-title":"Quantitative ultrasound and vertebral fracture in post menopausal women","volume":"10","author":"Bauer","year":"1995","journal-title":"J Bone Miner Res"},{"key":"2024013114244452400_bib18","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1118\/1.596039","article-title":"A study of the inhomogenetity of the trabecular bone mineral density in the calcaneus","volume":"14","author":"Shukla","year":"1987","journal-title":"Med Phys"},{"key":"2024013114244452400_bib19","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/0021-9290(91)90325-H","article-title":"Topographical distribution of trabecular bone strength in the human os calcanei","volume":"24","author":"Jensen","year":"1991","journal-title":"J Biomech"},{"key":"2024013114244452400_bib20","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1088\/0143-0815\/11\/3\/007","article-title":"A contact method for the assessment of ultrasonic velocity and broadband attenuation in cortical and cancellous bone","volume":"11","author":"Langton","year":"1990","journal-title":"Clin Phys Physiol Measure"},{"key":"2024013114244452400_bib21","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1007\/BF00298991","article-title":"Ultrasound and dual X-ray absorptiometry measurement of the calcaneus: influence of region of interest location","volume":"57","author":"Brooke-Wavell","year":"1995","journal-title":"Calcif Tissue Int"},{"key":"2024013114244452400_bib22","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1007\/BF00296055","article-title":"Broadband ultrasonic attenuation imaging: A new imaging technique of the os calcis","volume":"54","author":"Laugier","year":"1994","journal-title":"Calcif Tissue Int"},{"key":"2024013114244452400_bib23","doi-asserted-by":"crossref","first-page":"1137","DOI":"10.1002\/jbmr.5650080915","article-title":"Vertebral fracture assessment using a semi-quantitative technique","volume":"8","author":"Genant","year":"1993","journal-title":"J Bone Miner Res"},{"key":"2024013114244452400_bib24","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1088\/0031-9155\/40\/1\/012","article-title":"Factors affecting the in vivo precision of broadband ultrasonic attenuation","volume":"40","author":"Evans","year":"1995","journal-title":"Phys Med Biol"},{"key":"2024013114244452400_bib25","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1007\/BF00296056","article-title":"Comparison of broadband ultrasound attenuation to single X-ray absorptiometry measurements at the calcaneus in post menopausal women","volume":"54","author":"Salamone","year":"1994","journal-title":"Calcif Tissue Int"},{"key":"2024013114244452400_bib26","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1007\/BF01321830","article-title":"Measurements of post menopausal bone loss with a new contact ultrasound system","volume":"53","author":"Herd","year":"1993","journal-title":"Calcif Tissue Int"},{"key":"2024013114244452400_bib27","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1007\/BF02565130","article-title":"Ultrasound transmission measurements through the os calcis","volume":"49","author":"Zagzebski","year":"1991","journal-title":"Calcif Tissue Int"},{"key":"2024013114244452400_bib28","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1007\/BF00296673","article-title":"The relationship between ultrasound and densitometric measurements of bone mass at the calcaneus in women","volume":"51","author":"Waud","year":"1992","journal-title":"Calcif Tissue Int"},{"key":"2024013114244452400_bib29","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/8756-3282(89)90005-7","article-title":"In vitro comparison of quantitative computer tomography and broadband ultrasonic attenuation of trabecular bone","volume":"10","author":"McKelvie","year":"1989","journal-title":"Bone"},{"key":"2024013114244452400_bib30","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1042\/cs0780221","article-title":"Assessment of broadband ultrasound attenuation in the os calcis in vitro","volume":"78","author":"McCloskey","year":"1990","journal-title":"Clin Sci"},{"key":"2024013114244452400_bib31","first-page":"1479","author":"Laugier","year":"1994"},{"key":"2024013114244452400_bib32","doi-asserted-by":"crossref","first-page":"1071","DOI":"10.1002\/jbmr.5650070910","article-title":"Site-matched calcaneal measurements of broadband ultrasound attenuation and single X-ray absorptiometry: Do they measure different skeletal properties?","volume":"9","author":"Gl\u00fcer","year":"1992","journal-title":"J Bone Miner Res"},{"key":"2024013114244452400_bib33","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/8756-3282(94)00041-7","article-title":"Do ultrasound measurements on the os calcis reflect more the micro architecture of bone than the bone mass? A two-dimensional histomorphometric study","volume":"16","author":"Hans","year":"1995","journal-title":"Bone"},{"key":"2024013114244452400_bib34","first-page":"23","article-title":"New ultrasonic methods of quantitative assessment of bone status","volume":"1","author":"Laugier","year":"1994","journal-title":"Eur J Ultrasound"},{"key":"2024013114244452400_bib35","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1007\/BF01624149","article-title":"Measurements of broadband ultrasonic attenuation in the calcaneus in pre and postmenopausal women","volume":"2","author":"Herd","year":"1992","journal-title":"Osteoporosis Int"},{"key":"2024013114244452400_bib36","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1007\/BF00334544","article-title":"Ultrasound attenuation of the calcaneus in the female population: Normative data","volume":"51","author":"Damilakis","year":"1992","journal-title":"Calcif Tissue Int"},{"key":"2024013114244452400_bib37","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1007\/BF01622259","article-title":"Influence of antropometric parameters on ultrasound measurements of os calcis","volume":"5","author":"Hans","year":"1995","journal-title":"Osteoporosis Int"},{"key":"2024013114244452400_bib38","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1007\/BF00298738","article-title":"Dual-energy X-ray absorptiometry of the calcaneus: Comparison with vertebral dual-energy X-ray absorptiometry and quantitative computed tomography","volume":"56","author":"Laval-Jeantet","year":"1995","journal-title":"Calcif Tissue Int"},{"key":"2024013114244452400_bib39","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1007\/BF01623278","article-title":"Broadband ultrasound attenuation compared with dual-energy X-ray absorptiometry in screening for post menopausal low bone density","volume":"3","author":"Young","year":"1993","journal-title":"Osteoporosis Int"},{"key":"2024013114244452400_bib40","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1259\/0007-1285-66-781-55","article-title":"Measurement of the bone mineral density of the os calcis as an indication of vertebral fracture in women with lumbar osteoarthritis","volume":"66","author":"Kotzki","year":"1993","journal-title":"Br J Radiol"},{"key":"2024013114244452400_bib41","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1007\/BF00296338","article-title":"Ultrasound and densitometry of the calcaneus correlate with the failure loads of cadaveric femurs","volume":"56","author":"Bouxsein","year":"1995","journal-title":"Calcif Tissue Int"},{"key":"2024013114244452400_bib42","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1136\/bmj.301.6753.638","article-title":"Prediction of hip fracture in elderly women: A prospective study","volume":"301","author":"Porter","year":"1990","journal-title":"Br Med J"}],"container-title":["Journal of Bone and Mineral Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjbmr.5650110810","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/academic.oup.com\/jbmr\/article-pdf\/11\/8\/1112\/56503363\/5650110810.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jbmr\/article-pdf\/11\/8\/1112\/56503363\/5650110810.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,3,13]],"date-time":"2024-03-13T15:03:00Z","timestamp":1710342180000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jbmr\/article\/11\/8\/1112-1118\/7500917"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1996,8,1]]},"references-count":42,"journal-issue":{"issue":"8","published-online":{"date-parts":[[1996,8,1]]},"published-print":{"date-parts":[[1996,8,1]]}},"URL":"https:\/\/doi.org\/10.1002\/jbmr.5650110810","relation":{},"ISSN":["0884-0431","1523-4681"],"issn-type":[{"value":"0884-0431","type":"print"},{"value":"1523-4681","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[1996,8,1]]},"published":{"date-parts":[[1996,8,1]]}}}