{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,30]],"date-time":"2026-05-30T02:49:30Z","timestamp":1780109370912,"version":"3.54.0"},"reference-count":6,"publisher":"Oxford University Press (OUP)","issue":"S2","license":[{"start":{"date-parts":[[1999,11,1]],"date-time":"1999-11-01T00:00:00Z","timestamp":941414400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1999,11,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Pagetic sarcoma is a rare anaplastic malignancy with a peak incidence in the seventh and eighth decades of life; it usually occurs in patients with polyostotic Paget's disease. The most common tumor type is osteosarcoma. In one-third of the cases, presentation is a spontaneous pathologic fracture of an affected long bone. Amputation is the most appropriate form of surgical management in most cases because of the aggressive behavior of the sarcoma and its usually late presentation in this elderly population. However, selected patients with extremity lesions may be managed by pre- and postoperative chemotherapy and wide curative resection with limb salvage reconstruction. It is essential to differentiate pagetic sarcoma from metastatic carcinoma in pagetic bone and from a benign giant cell tumor.<\/jats:p>","DOI":"10.1002\/jbmr.5650140210","type":"journal-article","created":{"date-parts":[[2011,8,4]],"date-time":"2011-08-04T15:31:50Z","timestamp":1312471910000},"page":"45-48","source":"Crossref","is-referenced-by-count":11,"title":["Surgical management of neoplastic complications of paget's disease"],"prefix":"10.1093","volume":"14","author":[{"given":"Kevin D.","family":"Harrington","sequence":"first","affiliation":[{"name":"Department of Orthopaedic Surgery, California\u2014Pacific Medical Center and the University of California-San Francisco, San Francisco, California, U.S.A."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2011,8,4]]},"reference":[{"key":"2024020713333206300_bib1","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1302\/0301-620X.51B2.205","article-title":"Paget's sarcoma of bone: A study of eighty cases from the Bristol and Leeds bone tumour registries","volume":"51","author":"Price","year":"1969","journal-title":"J Bone Joint Surg Br"},{"key":"2024020713333206300_bib2","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1302\/0301-620X.65B3.6573330","article-title":"Sarcoma complicating Paget's disease of bone","volume":"65","author":"Schajowica","year":"1983","journal-title":"J Bone Joint Surg Br"},{"key":"2024020713333206300_bib3","doi-asserted-by":"crossref","first-page":"1489","DOI":"10.1002\/1097-0142(19831015)52:8<1489::AID-CNCR2820520826>3.0.CO;2-X","article-title":"Osteogenic sarcoma associated with Paget's disease of bone: A clinicopathologic study of sixty-five patients","volume":"52","author":"Huvos","year":"1983","journal-title":"Cancer"},{"key":"2024020713333206300_bib4","doi-asserted-by":"crossref","first-page":"1314","DOI":"10.2106\/00004623-195739060-00009","article-title":"Sarcoma in Paget's disease of bone","volume":"39","author":"Porretta","year":"1957","journal-title":"J Bone Joint Surg Am"},{"key":"2024020713333206300_bib5","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1302\/0301-620X.68B1.3941136","article-title":"Paget's disease and metastatic carcinoma. A case report","volume":"68","author":"Roberts","year":"1986","journal-title":"J Bone Joint Surg Br"},{"key":"2024020713333206300_bib6","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1097\/00003086-198803000-00047","article-title":"Metastases of carcinoma in Pagetic bone: A report of two cases","volume":"228","author":"Schajowicz","year":"1988","journal-title":"Clin Orthop"}],"container-title":["Journal of Bone and Mineral Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjbmr.5650140210","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/academic.oup.com\/jbmr\/article-pdf\/14\/S2\/45\/56598581\/5650140210.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jbmr\/article-pdf\/14\/S2\/45\/56598581\/5650140210.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,3,13]],"date-time":"2024-03-13T15:04:35Z","timestamp":1710342275000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jbmr\/article\/14\/S2\/45-48\/7514793"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1999,11,1]]},"references-count":6,"journal-issue":{"issue":"S2","published-online":{"date-parts":[[2011,8,4]]},"published-print":{"date-parts":[[1999,11,1]]}},"URL":"https:\/\/doi.org\/10.1002\/jbmr.5650140210","relation":{},"ISSN":["0884-0431","1523-4681"],"issn-type":[{"value":"0884-0431","type":"print"},{"value":"1523-4681","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[1999,11,1]]},"published":{"date-parts":[[1999,11,1]]}}}