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The purpose of this study was to evaluate the effect of the antioxidant curcumin (400 mg\/kg b.w.) on the K<jats:sub>2<\/jats:sub>Cr<jats:sub>2<\/jats:sub>O<jats:sub>7<\/jats:sub>\u2010induced injury, with special emphasis on ascitic fluid accumulation and oxidative phosphorylation mitochondrial enzymes and the adenosine triphosphate (ATP) levels in isolated mitochondria from livers of rats treated with K<jats:sub>2<\/jats:sub>Cr<jats:sub>2<\/jats:sub>O<jats:sub>7<\/jats:sub> (15 mg\/kg b.w.). Thus, curcumin attenuated the ascites generation, prevented the decrease in the activities of aconitase and F<jats:sub>1<\/jats:sub>F<jats:sub>0<\/jats:sub> ATPase, and maintained the ATP levels. The activity of complex II was not completely reestablished by curcumin, whereas complexes III and IV activities were unchanged.<\/jats:p>","DOI":"10.1002\/jbt.21595","type":"journal-article","created":{"date-parts":[[2014,8,6]],"date-time":"2014-08-06T13:57:47Z","timestamp":1407333467000},"page":"522-527","source":"Crossref","is-referenced-by-count":13,"title":["Curcumin Attenuates Cr(VI)\u2010Induced Ascites and Changes in the Activity of Aconitase and F<sub>1<\/sub>F<sub>0<\/sub> ATPase and the ATP Content in Rat Liver Mitochondria"],"prefix":"10.1002","volume":"28","author":[{"given":"Wylly Rams\u00e9s","family":"Garc\u00eda\u2010Ni\u00f1o","sequence":"first","affiliation":[{"name":"Faculty of Chemistry Department of Biology National Autonomous University of Mexico (UNAM) University City  04510 DF Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cecilia","family":"Zazueta","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Biomedicine National Institute of Cardiology \u201cIgnacio Ch\u00e1vez,\u201d  14080 DF Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edilia","family":"Tapia","sequence":"additional","affiliation":[{"name":"Department of Nephrology Laboratory of Renal Pathophysiology National Institute of Cardiology \u201cIgnacio Ch\u00e1vez,\u201d  14080 DF Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9","family":"Pedraza\u2010Chaverri","sequence":"additional","affiliation":[{"name":"Faculty of Chemistry Department of Biology National Autonomous University of Mexico (UNAM) University City  04510 DF Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,8,6]]},"reference":[{"key":"e_1_2_6_2_1","first-page":"106","article-title":"Chromium hexavalent compounds. 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