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Synephrine and phenylephrine had<jats:italic>K<\/jats:italic><jats:sub>i<\/jats:sub>values of 199.02\u00a0\u00b1\u00a016.01 and 65.01\u00a0\u00b1\u00a05.00\u00a0\u03bcM against hCA I and 336.02\u00a0\u00b1\u00a074.01 and 92.04 \u00a0\u00b1 \u00a018.03\u00a0\u03bcM against hCA II, respectively. On the other hand, their<jats:italic>K<\/jats:italic><jats:sub>i<\/jats:sub>values were found to be 169.10 \u00a0\u00b1 \u00a080.03 and 88.03 \u00a0\u00b1 \u00a05.01\u00a0nM against AChE and 177.06 \u00a0\u00b1 \u00a06.01 and 78.03 \u00a0\u00b1 \u00a03.05\u00a0nM against BChE, respectively. \u03b1\u2010Amylase and \u03b1\u2010glycosidase enzymes were easily inhibited by these compounds. \u03b1\u2010Glycosidase inhibitors, generally defined to as starch blockers, are anti\u2010diabetic drugs that help to decrease post comestible blood glucose levels.<\/jats:p>","DOI":"10.1002\/jbt.21973","type":"journal-article","created":{"date-parts":[[2017,8,11]],"date-time":"2017-08-11T12:52:39Z","timestamp":1502455959000},"source":"Crossref","is-referenced-by-count":139,"title":["Synephrine and phenylephrine act as \u03b1\u2010amylase, \u03b1\u2010glycosidase, acetylcholinesterase, butyrylcholinesterase, and carbonic anhydrase enzymes inhibitors"],"prefix":"10.1002","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3171-0633","authenticated-orcid":false,"given":"Parham","family":"Taslimi","sequence":"first","affiliation":[{"name":"Department of Chemistry, Faculty of Science Atat\u00fcrk University Erzurum 25240 Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H\u00fclya","family":"Ak\u0131nc\u0131oglu","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Faculty of Science and Arts Agri Ibrahim Cecen University Agri 04100 Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5993-1668","authenticated-orcid":false,"given":"\u0130lhami","family":"G\u00fcl\u00e7in","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Faculty of Science Atat\u00fcrk University Erzurum 25240 Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,8,11]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12012-013-9199-x"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fct.2010.11.007"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.3349\/ymj.2009.50.3.414"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.3344\/kjp.2014.27.3.229"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.3109\/14756366.2016.1160077"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmc.2015.04.019"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bioorg.2014.07.009"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/jbt.21897"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.3109\/14756366.2015.1135914"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bioorg.2015.04.006"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.3109\/14756366.2016.1170014"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.3109\/14756366.2016.1156104"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1080\/14756366.2016.1198901"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bioorg.2017.03.001"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02977396"},{"key":"e_1_2_6_17_1","first-page":"2850","volume":"6","author":"Kang W.","year":"2012","journal-title":"J. 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