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Spectral data and elemental analysis confirmed the structures of the compounds synthesized. The results show that all the synthesized compounds inhibited the CA I and II activities. Among them, 3a was found to be the most active (\n<jats:italic>K<\/jats:italic>\n<jats:sub>i<\/jats:sub>: 14\u2009\u00b5M) for hCA I and 3f (\n<jats:italic>K<\/jats:italic>\n<jats:sub>i<\/jats:sub>: 126\u2009\u00b5M) for hCA II.<\/jats:p>","DOI":"10.1002\/jbt.22306","type":"journal-article","created":{"date-parts":[[2019,2,27]],"date-time":"2019-02-27T19:23:16Z","timestamp":1551295396000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Synthesis of carbazole bearing pyridopyrimidine\u2010substituted sulfonamide derivatives and studies their carbonic anhydrase enzyme activity"],"prefix":"10.1002","volume":"33","author":[{"given":"Arleta","family":"Rifati\u2010Nixha","sequence":"first","affiliation":[{"name":"Department of Chemistry, Faculty of Mathematical &amp; Natural Sciences University of Prishtina Prishtina Republic of Kosova"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mustafa","family":"Arslan","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Faculty of Arts and Sciences Sakarya University Sakarya Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7092-8857","authenticated-orcid":false,"given":"Nahit","family":"Gen\u00e7er","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Faculty of Arts and Sciences Balikesir University Balikesir Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K\u00fcbra","family":"\u00c7\u0131kr\u0131k\u0131\u00e7\u0131","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Faculty of Arts and Sciences Balikesir University Balikesir Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8548-9703","authenticated-orcid":false,"given":"Ba\u015fak","family":"G\u00f6k\u00e7e","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, Faculty of Pharmacy Suleyman Demirel University Isparta Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Oktay","family":"Arslan","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Faculty of Arts and Sciences Balikesir University Balikesir Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,2,27]]},"reference":[{"issue":"3","key":"e_1_2_6_1_2_1","first-page":"120","volume":"5","author":"Dua R.","year":"2011","journal-title":"Adv. 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