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In continuation with\u00a0that, the present study aimed to investigate the pesticide\u2010induced neurochemical imbalance and its association with behavior alterations in agricultural workers. A significant increase in depressive symptoms, assessed by the Beck Depression Inventory\u2010II was observed in pesticide exposed workers as compared to the unexposed. A decrease in the level of dopamine in plasma and levels of dopamine, 3,4\u2010dihydroxyphenylacetic acid, homovanillic acids, norepinephrine, serotonin, and hydroxyindoleacetic acid in urine was also observed. An increase in the levels of MAO\u2010A and MAO\u2010B has also been observed in these individuals. The decreased levels of neurotransmitters in the blood and urine have been linked with increased levels of MAO and pesticide residues in plasma and urine. Furthermore, these changes were associated with a higher incidence\u00a0of depression in agricultural workers.<\/jats:p>","DOI":"10.1002\/jbt.22477","type":"journal-article","created":{"date-parts":[[2020,3,2]],"date-time":"2020-03-02T06:07:08Z","timestamp":1583129228000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":31,"title":["Identification of markers of depression and neurotoxicity in pesticide exposed agriculture workers"],"prefix":"10.1002","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1733-5101","authenticated-orcid":false,"given":"Rajesh K.","family":"Kori","sequence":"first","affiliation":[{"name":"Department of Criminology and Forensic Science, School of Applied Sciences Dr. Harisingh Gour Vishwavidyalaya (A Central University)  Sagar Madhya Pradesh India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kapil","family":"Mandrah","sequence":"additional","affiliation":[{"name":"Academy of Scientific and Innovative Research (AcSIR) CSIR\u2010IITR Campus  Lucknow Uttar Pradesh India"},{"name":"Analytical Chemistry Laboratory, Regulatory Toxicology Group CSIR\u2010Indian Institute of Toxicology Research  Lucknow Uttar Pradesh India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1305-1264","authenticated-orcid":false,"given":"Whidul","family":"Hasan","sequence":"additional","affiliation":[{"name":"Department of Zoology, School of Biological Sciences Dr. Harisingh Gour Vishwavidyalaya (A Central University)  Sagar Madhya Pradesh India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Devendra K.","family":"Patel","sequence":"additional","affiliation":[{"name":"Academy of Scientific and Innovative Research (AcSIR) CSIR\u2010IITR Campus  Lucknow Uttar Pradesh India"},{"name":"Analytical Chemistry Laboratory, Regulatory Toxicology Group CSIR\u2010Indian Institute of Toxicology Research  Lucknow Uttar Pradesh India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Somendu K.","family":"Roy","sequence":"additional","affiliation":[{"name":"Academy of Scientific and Innovative Research (AcSIR) CSIR\u2010IITR Campus  Lucknow Uttar Pradesh India"},{"name":"Analytical Chemistry Laboratory, Regulatory Toxicology Group CSIR\u2010Indian Institute of Toxicology Research  Lucknow Uttar Pradesh India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1754-6187","authenticated-orcid":false,"given":"Rajesh S.","family":"Yadav","sequence":"additional","affiliation":[{"name":"Department of Criminology and Forensic Science, School of Applied Sciences Dr. Harisingh Gour Vishwavidyalaya (A Central University)  Sagar Madhya Pradesh India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,3]]},"reference":[{"key":"e_1_2_8_2_1","first-page":"232","volume":"2","author":"Kumar B.","year":"2012","journal-title":"Asian J. 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