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This review aims\u00a0to give an overview of the risk of AKI, RRT, and associated mortality among the patients who received ECMO for any of its indications. PubMed database was searched to find the relevant literature and the reference list of included studies was also searched for additional studies. The incidence of AKI ranged from 30% to 78% and RRT from 47% to 60% in ECMO patients. The pathophysiology of AKI in ECMO is multifactorial,\u00a0and\u00a0includes ischaemia, RBCs breakdown, comorbidity, conversion of zymogen form of pro\u2010inflammatory mediators, structural alteration of the kidney, coadministration of nephrotoxic drugs, coagulation abnormality, and oxidative stress. ECMO was associated with the higher incidence of renal abnormalities, AKI, requirement of RRT, and associated mortality. Patients who underwent\u00a0RRT had improved renal function and reduced overall mortality compared to the non\u2010RRT group among the ECMO patients. Currently, there is no consensus evidence to support the superior use of the inline hemofilter system over continuous renal replacement therapy among patients who had AKI during ECMO.<\/jats:p>","DOI":"10.1002\/jbt.22679","type":"journal-article","created":{"date-parts":[[2020,12,16]],"date-time":"2020-12-16T22:02:22Z","timestamp":1608156142000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["A review on extracorporeal membrane oxygenation and kidney injury"],"prefix":"10.1002","volume":"35","author":[{"given":"Ming","family":"Gu","sequence":"first","affiliation":[{"name":"Department of Emergency and Critical Care Medicine The Second Hospital of Jilin University Changchun Jilin China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiang\u2010Lin","family":"Mei","sequence":"additional","affiliation":[{"name":"Department of Pathology The Second Hospital of Jilin University Changchun Jilin China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5066-7039","authenticated-orcid":false,"given":"Ya\u2010Nan","family":"Zhao","sequence":"additional","affiliation":[{"name":"Neurology Department China\u2013Japan Union Hospital of Jilin University Changchun Jilin China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,12,16]]},"reference":[{"key":"e_1_2_15_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/MAT.0000000000000179"},{"key":"e_1_2_15_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0000000000003465"},{"key":"e_1_2_15_4_1","doi-asserted-by":"publisher","DOI":"10.5935\/0103-507X.20190063"},{"key":"e_1_2_15_5_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13054-018-2134-6"},{"key":"e_1_2_15_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2012.03.013"},{"key":"e_1_2_15_7_1","doi-asserted-by":"publisher","DOI":"10.1615\/JEnvironPatholToxicolOncol.2020033025"},{"key":"e_1_2_15_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/MCC.0000000000000309"},{"key":"e_1_2_15_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.aan.2017.07.006"},{"key":"e_1_2_15_10_1","first-page":"e14209","author":"Gupta G.","year":"2020","journal-title":"Dermatol. 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