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Forty rats were divided into four groups; the first group was used as a control group, the second group was exposed to Res only at a dose of 20\u2009mg\/kg body weight for 4 weeks, and the third group was administered CM only at a dose of 799\u2009mg\/kg body weight for 4 weeks, The fourth group was co\u2010treated with Res+CM for 4 weeks. Blood samples were analyzed for hematological and biochemical parameters. The comet assay was done on liver and blood specimens and histopathological examinations of the liver and intestine. The results demonstrated that CM exposure caused a significant increase in WBCs, lymphocytes, granulocytes, monocytes ALT, AST, ALP, and GGT, and total cholesterol and triglycerides levels accompanied by a decrease in HGB, HCT, RBCs and MCV, MCH, MCHC, HDL and glucose levels with no significant DNA damage in liver and blood. CM mixture induced severe pathological changes in small intestine and liver. Co\u2010treatment of Res with CM improved hematological picture, lipid and glucose profiles also liver enzymes and decreased changes in the architecture of the liver and intestine.<\/jats:p>","DOI":"10.1002\/jbt.23347","type":"journal-article","created":{"date-parts":[[2023,4,3]],"date-time":"2023-04-03T09:10:25Z","timestamp":1680513025000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Ameliorative effect of resveratrol against cymoxanil\u2010mancozeb induced toxicity in rats"],"prefix":"10.1002","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6210-6861","authenticated-orcid":false,"given":"Wafaa H.","family":"Mohamed","sequence":"first","affiliation":[{"name":"Department of Forensic Medicine and Toxicology, Faculty of Veterinary Medicine Aswan University Sahary City Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasmin O.","family":"El\u2010Amir","sequence":"additional","affiliation":[{"name":"Department of Veterinary Pathology and Clinical Pathology, Faculty of Veterinary Medicine Assiut University Assiut Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Doha","family":"Yahia","sequence":"additional","affiliation":[{"name":"Department of Forensic Medicine and Toxicology, Faculty of Veterinary Medicine Assiut University Assiut Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,4,3]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/ps.5332"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph16010146"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2020.139033"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chemosphere.2020.125870"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/elan.201500633"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.3390\/ani10122205"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ecoenv.2020.111339"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chemosphere.2014.11.061"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph17072580"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.envint.2016.11.006"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.lfs.2019.117078"},{"key":"e_1_2_7_13_1","first-page":"323","volume":"2011","author":"Rath N. 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