{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T04:04:52Z","timestamp":1791950692376,"version":"4.3.4"},"reference-count":204,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,12,29]],"date-time":"2025-12-29T00:00:00Z","timestamp":1766966400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,12,29]],"date-time":"2025-12-29T00:00:00Z","timestamp":1766966400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Biochem &amp;amp; Molecular Tox"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Parkinson's disease (PD) is an idiopathic and age\u2010related neurodegenerative disorder, marked by the selective loss of dopaminergic neurons in the SNpc and the formation of\n                    <jats:italic>\u03b1<\/jats:italic>\n                    \u2010synuclein aggregates. Consequently, this leads to motor and non\u2010motor complications in PD\u2010like patients. Research on plant\u2010based secondary metabolites, such as polyphenols, confirmed that they may slow the development and progression of PD. Flavonoids generated the peak of interest due to their medicinal properties, including mitigation of the risk of PD. Quercetin, a subclass of flavonol type of flavonoids, attracted attention as a potential neuroprotective agent. Quercetin has been demonstrated to have anti\u2010oxidant, anti\u2010inflammatory, anti\u2010apoptotic, and neuroprotective properties, along with obstruction of \u03b1\u2010synuclein accumulation and mitochondrial protection. Moreover, studies also revealed that quercetin ameliorates the striatal dopamine content and distinctly modulates the various signalling pathways, including PI3K\/AKT, Nrf2, MAPK and NF\u2010kB that are involved in the disruption of disease. Further, quercetin modulates oxidative stress through upregulation of anti\u2010oxidant enzymes, inhibits neuroinflammation via suppression of pro\u2010inflammatory cytokines, prevents Lewy bodies formation and regulates autophagy along with apoptosis. By exhibiting the aforementioned effects, quercetin protects against the neuronal toxicity induced by various neurotoxins through multiple mechanisms to improve motor and non\u2010motor functions. This highlights quercetin as a potential multifaceted therapeutic candidate for PD intervention. We searched for the published data on quercetin related to PD and summarized them in the current review. This review aims to address the understanding of mechanisms, therapeutic effects of quercetin and various models using neurotoxins to induce PD. This review aims to elucidate the underlying cellular and molecular mechanisms and therapeutic effects of quercetin, as well as to explore the various neurotoxin\u2010induced models of PD used to investigate its efficacy. The major part of this review article discusses the roles of quercetin in the management of PD in animals of several experimental models used by many research studies. Overall, quercetin represents a promising, safe, effective and potentially neuroprotective candidate for disease disease\u2010modifying strategy to combat neurological disorders such as PD.\n                  <\/jats:p>","DOI":"10.1002\/jbt.70656","type":"journal-article","created":{"date-parts":[[2025,12,29]],"date-time":"2025-12-29T10:41:20Z","timestamp":1767004880000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Unveiling the Potential of Flavonoids in the Regulation of Parkinson's Disease: Special Focus on Quercetin"],"prefix":"10.1002","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5625-5067","authenticated-orcid":false,"given":"Niraj Kumar","family":"Singh","sequence":"first","affiliation":[{"name":"Institute of Pharmaceutical Research Mathura Uttar Pradesh India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-1268-4581","authenticated-orcid":false,"given":"Kamini","family":"Solanki","sequence":"additional","affiliation":[{"name":"Institute of Pharmaceutical Research Mathura Uttar Pradesh India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,12,29]]},"reference":[{"key":"e_1_2_15_2_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms21061961"},{"key":"e_1_2_15_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(21)00218-X"},{"key":"e_1_2_15_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2019.03.001"},{"key":"e_1_2_15_5_1","doi-asserted-by":"publisher","DOI":"10.12786\/bn.2022.15.e15"},{"key":"e_1_2_15_6_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms22147630"},{"key":"e_1_2_15_7_1","doi-asserted-by":"publisher","DOI":"10.3390\/cells11111732"},{"key":"e_1_2_15_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(21)00030-2"},{"key":"e_1_2_15_9_1","doi-asserted-by":"publisher","DOI":"10.3390\/biom11040612"},{"key":"e_1_2_15_10_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2022.1011740"},{"key":"e_1_2_15_11_1","doi-asserted-by":"publisher","DOI":"10.2174\/0118715249264078231214074107"},{"key":"e_1_2_15_12_1","doi-asserted-by":"publisher","DOI":"10.2741\/S415"},{"key":"e_1_2_15_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nbd.2019.104700"},{"key":"e_1_2_15_14_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms23115954"},{"key":"e_1_2_15_15_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu13062099"},{"key":"e_1_2_15_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cca.2021.08.009"},{"key":"e_1_2_15_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12264-017-0183-5"},{"key":"e_1_2_15_18_1","doi-asserted-by":"publisher","DOI":"10.1177\/1535370221989263"},{"key":"e_1_2_15_19_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40001-024-01779-7"},{"key":"e_1_2_15_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jphs.2020.07.011"},{"key":"e_1_2_15_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tins.2013.06.003"},{"key":"e_1_2_15_22_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10571-025-01544-2"},{"key":"e_1_2_15_23_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awae355"},{"key":"e_1_2_15_24_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00018-022-04240-2"},{"key":"e_1_2_15_25_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40035-022-00293-2"},{"key":"e_1_2_15_26_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41419-023-05672-9"},{"key":"e_1_2_15_27_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms21228645"},{"key":"e_1_2_15_28_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-022-05319-3"},{"key":"e_1_2_15_29_1","doi-asserted-by":"publisher","DOI":"10.1002\/brb3.2628"},{"key":"e_1_2_15_30_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40478-024-01797-w"},{"key":"e_1_2_15_31_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10787-023-01384-w"},{"key":"e_1_2_15_32_1","doi-asserted-by":"publisher","DOI":"10.1155\/2022\/7934442"},{"key":"e_1_2_15_33_1","doi-asserted-by":"publisher","DOI":"10.1111\/acel.13031"},{"key":"e_1_2_15_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.expneurol.2017.06.017"},{"key":"e_1_2_15_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nbd.2022.105851"},{"key":"e_1_2_15_36_1","doi-asserted-by":"publisher","DOI":"10.18632\/aging.202951"},{"key":"e_1_2_15_37_1","first-page":"1","volume-title":"Oxid Med Cell Longev","author":"Perc\u00e1rio S.","year":"2020"},{"key":"e_1_2_15_38_1","doi-asserted-by":"publisher","DOI":"10.1155\/padi\/6691390"},{"key":"e_1_2_15_39_1","doi-asserted-by":"publisher","DOI":"10.1515\/almed-2022-0111"},{"key":"e_1_2_15_40_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.27776"},{"key":"e_1_2_15_41_1","doi-asserted-by":"publisher","DOI":"10.1080\/00207454.2017.1325883"},{"key":"e_1_2_15_42_1","doi-asserted-by":"publisher","DOI":"10.4103\/1673-5374.380878"},{"key":"e_1_2_15_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nbd.2025.106889"},{"key":"e_1_2_15_44_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms242317027"},{"key":"e_1_2_15_45_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mehy.2015.08.018"},{"key":"e_1_2_15_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neurot.2023.10.002"},{"key":"e_1_2_15_47_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms26094451"},{"key":"e_1_2_15_48_1","doi-asserted-by":"publisher","DOI":"10.1042\/BCJ20253062"},{"key":"e_1_2_15_49_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13024-023-00676-7"},{"key":"e_1_2_15_50_1","doi-asserted-by":"publisher","DOI":"10.3390\/biom11101508"},{"key":"e_1_2_15_51_1","doi-asserted-by":"publisher","DOI":"10.3233\/JPD-201981"},{"key":"e_1_2_15_52_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12264-023-01023-y"},{"key":"e_1_2_15_53_1","doi-asserted-by":"publisher","DOI":"10.3390\/cells9071687"},{"key":"e_1_2_15_54_1","doi-asserted-by":"publisher","DOI":"10.3390\/cells12071012"},{"key":"e_1_2_15_55_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11910-022-01207-5"},{"key":"e_1_2_15_56_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms21228421"},{"key":"e_1_2_15_57_1","doi-asserted-by":"publisher","DOI":"10.4274\/balkanmedj.galenos.2022.2022-7-100"},{"key":"e_1_2_15_58_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuint.2021.105014"},{"key":"e_1_2_15_59_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2024.113015"},{"key":"e_1_2_15_60_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms23084148"},{"key":"e_1_2_15_61_1","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/324521"},{"key":"e_1_2_15_62_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmb.2023.168144"},{"key":"e_1_2_15_63_1","doi-asserted-by":"publisher","DOI":"10.1155\/2020\/8865611"},{"key":"e_1_2_15_64_1","doi-asserted-by":"publisher","DOI":"10.2174\/1570159X13666151030103027"},{"key":"e_1_2_15_65_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms232314997"},{"key":"e_1_2_15_66_1","doi-asserted-by":"publisher","DOI":"10.12659\/MSM.938519"},{"key":"e_1_2_15_67_1","doi-asserted-by":"publisher","DOI":"10.3390\/biom13101435"},{"key":"e_1_2_15_68_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmb.2020.01.037"},{"key":"e_1_2_15_69_1","doi-asserted-by":"publisher","DOI":"10.3390\/cells10123547"},{"key":"e_1_2_15_70_1","doi-asserted-by":"publisher","DOI":"10.3390\/cells12040621"},{"key":"e_1_2_15_71_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neulet.2018.04.013"},{"key":"e_1_2_15_72_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jneuroim.2021.577758"},{"key":"e_1_2_15_73_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejphar.2024.176878"},{"key":"e_1_2_15_74_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.27878"},{"key":"e_1_2_15_75_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11033-023-08459-5"},{"key":"e_1_2_15_76_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2024.02.023"},{"key":"e_1_2_15_77_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuint.2022.105389"},{"key":"e_1_2_15_78_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12935-025-03681-6"},{"key":"e_1_2_15_79_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2020.106210"},{"key":"e_1_2_15_80_1","doi-asserted-by":"publisher","DOI":"10.1186\/s11658-022-00355-3"},{"key":"e_1_2_15_81_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clim.2016.09.014"},{"key":"e_1_2_15_82_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.4658-15.2016"},{"key":"e_1_2_15_83_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12974-024-03210-8"},{"key":"e_1_2_15_84_1","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2017.00021"},{"key":"e_1_2_15_85_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12035-025-05113-y"},{"key":"e_1_2_15_86_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ctrv.2003.07.007"},{"key":"e_1_2_15_87_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12640-019-0003-y"},{"key":"e_1_2_15_88_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yexmp.2022.104846"},{"key":"e_1_2_15_89_1","doi-asserted-by":"publisher","DOI":"10.32604\/or.2022.025323"},{"key":"e_1_2_15_90_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2021.648636"},{"key":"e_1_2_15_91_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phrs.2024.107300"},{"key":"e_1_2_15_92_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00432-023-05572-7"},{"key":"e_1_2_15_93_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbadis.2009.12.009"},{"key":"e_1_2_15_94_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11011-025-01597-8"},{"key":"e_1_2_15_95_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnagi.2021.713201"},{"key":"e_1_2_15_96_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neubiorev.2014.12.005"},{"key":"e_1_2_15_97_1","doi-asserted-by":"publisher","DOI":"10.1111\/jsr.13902"},{"key":"e_1_2_15_98_1","doi-asserted-by":"publisher","DOI":"10.4103\/bc.bc_42_19"},{"key":"e_1_2_15_99_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuint.2020.104754"},{"key":"e_1_2_15_100_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules25225474"},{"key":"e_1_2_15_101_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules27051471"},{"key":"e_1_2_15_102_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jnutbio.2015.08.001"},{"key":"e_1_2_15_103_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuint.2022.105325"},{"key":"e_1_2_15_104_1","doi-asserted-by":"publisher","DOI":"10.3390\/antiox13091125"},{"key":"e_1_2_15_105_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu17213376"},{"key":"e_1_2_15_106_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms22179592"},{"key":"e_1_2_15_107_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biochi.2023.03.001"},{"key":"e_1_2_15_108_1","doi-asserted-by":"publisher","DOI":"10.1111\/acel.13101"},{"key":"e_1_2_15_109_1","doi-asserted-by":"publisher","DOI":"10.3390\/diseases11030089"},{"key":"e_1_2_15_110_1","first-page":"1","volume-title":"International Journal of Cell Biology","author":"Anand A. A.","year":"2023"},{"key":"e_1_2_15_111_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41392-021-00762-6"},{"key":"e_1_2_15_112_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2021.111596"},{"key":"e_1_2_15_113_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cbi.2025.111489"},{"key":"e_1_2_15_114_1","doi-asserted-by":"publisher","DOI":"10.1089\/jmf.2017.4078"},{"key":"e_1_2_15_115_1","doi-asserted-by":"publisher","DOI":"10.2147\/DDDT.S515004"},{"key":"e_1_2_15_116_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules25225243"},{"key":"e_1_2_15_117_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules28134982"},{"key":"e_1_2_15_118_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms23042176"},{"key":"e_1_2_15_119_1","doi-asserted-by":"publisher","DOI":"10.1002\/ptr.7309"},{"key":"e_1_2_15_120_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11064-020-03058-3"},{"key":"e_1_2_15_121_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules27196545"},{"key":"e_1_2_15_122_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules28248141"},{"key":"e_1_2_15_123_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnut.2022.999752"},{"key":"e_1_2_15_124_1","doi-asserted-by":"publisher","DOI":"10.3390\/medicina61040656"},{"key":"e_1_2_15_125_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules27082498"},{"key":"e_1_2_15_126_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2021.665031"},{"key":"e_1_2_15_127_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0258928"},{"key":"e_1_2_15_128_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2021.111729"},{"key":"e_1_2_15_129_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpha.2023.12.020"},{"key":"e_1_2_15_130_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2021.114068"},{"key":"e_1_2_15_131_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2024.1389179"},{"key":"e_1_2_15_132_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2022.968226"},{"key":"e_1_2_15_133_1","doi-asserted-by":"publisher","DOI":"10.3390\/foods9030374"},{"key":"e_1_2_15_134_1","doi-asserted-by":"publisher","DOI":"10.1155\/2021\/6678662"},{"key":"e_1_2_15_135_1","doi-asserted-by":"publisher","DOI":"10.2174\/09298673113209990120"},{"key":"e_1_2_15_136_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2021.689044"},{"key":"e_1_2_15_137_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2022.113447"},{"key":"e_1_2_15_138_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12906-022-03758-z"},{"key":"e_1_2_15_139_1","doi-asserted-by":"publisher","DOI":"10.21873\/anticanres.14469"},{"key":"e_1_2_15_140_1","doi-asserted-by":"publisher","DOI":"10.12688\/f1000research.141268.2"},{"key":"e_1_2_15_141_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v28.i11.1139"},{"key":"e_1_2_15_142_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules26226949"},{"key":"e_1_2_15_143_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11033-024-09617-z"},{"key":"e_1_2_15_144_1","article-title":"Antibiofilm Activity of Allicin and Quercetin in Treating Biofilm\u2010Associated Orthopaedics Infection","author":"Zhang H.","year":"2022","journal-title":"Applied Biochemistry and Biotechnology"},{"key":"e_1_2_15_145_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40203-022-00132-2"},{"key":"e_1_2_15_146_1","doi-asserted-by":"publisher","DOI":"10.1039\/c2fo10268d"},{"key":"e_1_2_15_147_1","doi-asserted-by":"publisher","DOI":"10.1089\/ped.2019.1137"},{"key":"e_1_2_15_148_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13205-019-1618-7"},{"key":"e_1_2_15_149_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsomega.2c08242"},{"key":"e_1_2_15_150_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-020-57658-8"},{"key":"e_1_2_15_151_1","doi-asserted-by":"publisher","DOI":"10.3390\/ph14030248"},{"key":"e_1_2_15_152_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2024.117369"},{"key":"e_1_2_15_153_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu14224871"},{"key":"e_1_2_15_154_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2021.107435"},{"key":"e_1_2_15_155_1","doi-asserted-by":"publisher","DOI":"10.4103\/JAPTR.JAPTR_496_23"},{"key":"e_1_2_15_156_1","doi-asserted-by":"publisher","DOI":"10.1186\/s10020-024-00929-1"},{"key":"e_1_2_15_157_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.heliyon.2022.e11159"},{"key":"e_1_2_15_158_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tice.2024.102313"},{"key":"e_1_2_15_159_1","doi-asserted-by":"publisher","DOI":"10.1080\/01616412.2023.2194182"},{"key":"e_1_2_15_160_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12935-022-02677-w"},{"key":"e_1_2_15_161_1","doi-asserted-by":"publisher","DOI":"10.1002\/ptr.6155"},{"key":"e_1_2_15_162_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms24076328"},{"key":"e_1_2_15_163_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbr.2025.115692"},{"key":"e_1_2_15_164_1","doi-asserted-by":"publisher","DOI":"10.1111\/bcpt.14011"},{"key":"e_1_2_15_165_1","doi-asserted-by":"publisher","DOI":"10.1080\/0886022X.2024.2327495"},{"key":"e_1_2_15_166_1","doi-asserted-by":"publisher","DOI":"10.1155\/2022\/7769355"},{"issue":"6","key":"e_1_2_15_167_1","first-page":"599","article-title":"Effects of Quercetin on Spatial Memory, Hippocampal Antioxidant Defense and BDNF Concentration in a Rat Model of Parkinson's Disease: An Electrophysiological Study","volume":"11","author":"Naghizadeh M.","year":"2021","journal-title":"Avicenna Journal of Phytomedicine"},{"key":"e_1_2_15_168_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2024.1519649"},{"key":"e_1_2_15_169_1","doi-asserted-by":"publisher","DOI":"10.3390\/biomedicines11102756"},{"key":"e_1_2_15_170_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cbi.2023.110610"},{"key":"e_1_2_15_171_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sjbs.2023.103792"},{"key":"e_1_2_15_172_1","doi-asserted-by":"publisher","DOI":"10.31083\/j.fbl2803042"},{"key":"e_1_2_15_173_1","doi-asserted-by":"publisher","DOI":"10.3390\/antiox11071378"},{"key":"e_1_2_15_174_1","doi-asserted-by":"publisher","DOI":"10.18632\/aging.202868"},{"key":"e_1_2_15_175_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10787-025-01712-2"},{"key":"e_1_2_15_176_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.colsurfb.2025.114752"},{"key":"e_1_2_15_177_1","doi-asserted-by":"publisher","DOI":"10.1002\/jbt.23165"},{"key":"e_1_2_15_178_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuro.2022.03.004"},{"issue":"6","key":"e_1_2_15_179_1","first-page":"1655","article-title":"Inhibition of Drug Induced Parkinsonism by Chronic Supplementation of Quercetin in Haloperidol\u2010Treated Wistars","volume":"35","author":"Rafiq H.","year":"2022","journal-title":"Pakistan Journal of Pharmaceutical Sciences"},{"key":"e_1_2_15_180_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12272-020-01238-x"},{"key":"e_1_2_15_181_1","doi-asserted-by":"publisher","DOI":"10.32598\/bcn.9.5.317"},{"key":"e_1_2_15_182_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2018.01383"},{"key":"e_1_2_15_183_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules22071122"},{"key":"e_1_2_15_184_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms18091989"},{"key":"e_1_2_15_185_1","doi-asserted-by":"publisher","DOI":"10.1111\/jnc.14033"},{"key":"e_1_2_15_186_1","doi-asserted-by":"publisher","DOI":"10.1002\/jbt.21821"},{"key":"e_1_2_15_187_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neurobiolaging.2016.06.015"},{"key":"e_1_2_15_188_1","doi-asserted-by":"publisher","DOI":"10.1080\/10286020.2015.1057576"},{"key":"e_1_2_15_189_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroscience.2016.02.055"},{"key":"e_1_2_15_190_1","doi-asserted-by":"publisher","DOI":"10.1097\/WNR.0000000000000667"},{"key":"e_1_2_15_191_1","doi-asserted-by":"publisher","DOI":"10.4103\/1673-5374.160106"},{"key":"e_1_2_15_192_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11064-015-1542-0"},{"key":"e_1_2_15_193_1","doi-asserted-by":"publisher","DOI":"10.2131\/jts.38.25"},{"key":"e_1_2_15_194_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroscience.2013.01.032"},{"key":"e_1_2_15_195_1","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/823206"},{"key":"e_1_2_15_196_1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2012\/928643","article-title":"Effect of Quercetin in the 1\u2010Methyl\u20104\u2010phenyl\u20101, 2, 3, 6\u2010tetrahydropyridine\u2010Induced Mouse Model of Parkinson's Disease","volume":"2012","author":"Lv C.","year":"2012","journal-title":"Evidence\u2010Based Complement Altern Med"},{"key":"e_1_2_15_197_1","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/921941"},{"key":"e_1_2_15_198_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cbi.2011.12.007"},{"key":"e_1_2_15_199_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neulet.2011.06.021"},{"key":"e_1_2_15_200_1","doi-asserted-by":"publisher","DOI":"10.3892\/ijmm.2010.571"},{"key":"e_1_2_15_201_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neures.2017.10.006"},{"key":"e_1_2_15_202_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12640-019-00120-z"},{"key":"e_1_2_15_203_1","doi-asserted-by":"publisher","DOI":"10.4103\/1673-5374.211194"},{"key":"e_1_2_15_204_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2007.02.017"},{"key":"e_1_2_15_205_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrneurol.2014.226"}],"container-title":["Journal of Biochemical and Molecular Toxicology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jbt.70656","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/jbt.70656","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jbt.70656","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T12:28:17Z","timestamp":1777552097000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jbt.70656"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,29]]},"references-count":204,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1]]}},"alternative-id":["10.1002\/jbt.70656"],"URL":"https:\/\/doi.org\/10.1002\/jbt.70656","archive":["Portico"],"relation":{},"ISSN":["1095-6670","1099-0461"],"issn-type":[{"value":"1095-6670","type":"print"},{"value":"1099-0461","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,12,29]]},"assertion":[{"value":"2025-11-07","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-12-16","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-12-29","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70656"}}