{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T09:08:22Z","timestamp":1789549702589,"version":"build-2803163510"},"reference-count":178,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T00:00:00Z","timestamp":1787702400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T00:00:00Z","timestamp":1787702400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Biochem &amp;amp; Molecular Tox"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Parkinson's disease (PD) is a common neurodegenerative disease threatening the health of the middle\u2010aged and elderly population, triggered by the combined effects of genetic susceptibility, environmental exposure and nervous system aging, among which atmospheric aerosol exposure is a key risk factor for sporadic PD. As a complex heterogeneous mixture, atmospheric aerosols contain neurotoxic components such as metal particles, persistent organic pollutants (POPs), and nano\/ultrafine particles, which appear to target midbrain substantia nigra dopaminergic neurons through pathways including direct entry into the brain via the olfactory pathway, penetration across the lung\u2010blood\u2010brain barrier, and inflammation\u2010mediated alterations in barrier permeability. The core molecular mechanisms that have been proposed to link aerosol exposure to sporadic PD include oxidative stress and mitochondrial dysfunction, neuroinflammation and aberrant microglial activation, disrupted protein homeostasis and abnormal aggregation of \u03b1\u2010synuclein (\u03b1\u2010syn), as well as altered epigenetic regulation. Moreover, neurotoxic effects may be amplified via the positive feedback loop of oxidative stress\u2010neuroinflammation, the vicious cycle of mitophagy defects and protein aggregation, and the \u201cmultiple\u2010hit hypothesis\u201d. This review summarizes the toxic components of aerosols, their brain\u2010entry routes and pathogenic mechanisms, outlines the application status of emerging technologies such as in vitro cell models and in vivo animal models, and sorts out intervention strategies including pharmacological therapy and epigenetic regulation. It also analyzes the current challenges in research on mechanisms, models, population studies and intervention strategies, and points out that future research should focus on dissecting the synergistic mechanisms of multiple components and optimizing research models, so as to provide theoretical support for exploring potential strategies for precise prevention, control and treatment of PD.<\/jats:p>","DOI":"10.1002\/jbt.71089","type":"journal-article","created":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T15:48:01Z","timestamp":1787759281000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Atmospheric Aerosol Neurotoxicity and Parkinson's Disease: Mechanisms and Perspectives"],"prefix":"10.1002","volume":"40","author":[{"given":"Yitian","family":"Gao","sequence":"first","affiliation":[{"name":"College of Geographical Sciences, Faculty of Geographical Science and Engineering Henan University Kaifeng China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Minxiang","family":"Dong","sequence":"additional","affiliation":[{"name":"The Second Affiliated Hospital of Inner Mongolia Medical University Inner Mongolia Medical University Hohhot China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chenyang","family":"Duan","sequence":"additional","affiliation":[{"name":"Huaihe Hospital of Henan University Henan University Kaifeng China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaohan","family":"Zheng","sequence":"additional","affiliation":[{"name":"College of Geographical Sciences, Faculty of Geographical Science and Engineering Henan University Kaifeng China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-3765-3442","authenticated-orcid":false,"given":"Liming","family":"Qu","sequence":"additional","affiliation":[{"name":"College of Geographical Sciences, Faculty of Geographical Science and Engineering Henan University Kaifeng China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,26]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41531-024-00779-y"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj-2024-080952"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.3233\/JPD-230357"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.arr.2026.103070"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.3233\/JPD-240019"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41531-025-01010-2"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.envint.2026.110377"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(25)00287-X"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13195-026-02050-3"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuro.2025.103353"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp-2024-334825"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.heliyon.2020.e04691"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.3390\/antiox14060730"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.envres.2024.119592"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbagen.2019.06.010"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/pro.4956"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtemb.2025.127721"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms25189759"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.puhe.2024.10.035"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.1080\/10937404.2022.2164390"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.3390\/toxics13070596"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2020.142649"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13024-025-00915-z"},{"key":"e_1_2_11_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.lfs.2019.01.056"},{"key":"e_1_2_11_26_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201801362"},{"key":"e_1_2_11_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhazmat.2024.134054"},{"key":"e_1_2_11_28_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12989-022-00490-x"},{"key":"e_1_2_11_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nbd.2025.107173"},{"key":"e_1_2_11_30_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.4c14571"},{"key":"e_1_2_11_31_1","doi-asserted-by":"publisher","DOI":"10.3390\/metabo15070487"},{"key":"e_1_2_11_32_1","doi-asserted-by":"publisher","DOI":"10.1039\/D5EM00166H"},{"key":"e_1_2_11_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2025.178853"},{"key":"e_1_2_11_34_1","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.adn3028"},{"key":"e_1_2_11_35_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41577-023-00972-9"},{"key":"e_1_2_11_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.envint.2020.105714"},{"key":"e_1_2_11_37_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-020-76332-7"},{"key":"e_1_2_11_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chemosphere.2024.141227"},{"key":"e_1_2_11_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuro.2026.103394"},{"key":"e_1_2_11_40_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12987-021-00250-7"},{"key":"e_1_2_11_41_1","doi-asserted-by":"publisher","DOI":"10.1177\/09603271231191436"},{"key":"e_1_2_11_42_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrestox.1c00353"},{"key":"e_1_2_11_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbi.2022.09.002"},{"key":"e_1_2_11_44_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41392-023-01588-0"},{"key":"e_1_2_11_45_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41423-021-00757-x"},{"key":"e_1_2_11_46_1","doi-asserted-by":"publisher","DOI":"10.3390\/antiox13101256"},{"key":"e_1_2_11_47_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41570-021-00310-4"},{"key":"e_1_2_11_48_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms25094753"},{"key":"e_1_2_11_49_1","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.83743"},{"key":"e_1_2_11_50_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sbi.2019.03.001"},{"key":"e_1_2_11_51_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.redox.2020.101545"},{"key":"e_1_2_11_52_1","doi-asserted-by":"publisher","DOI":"10.2174\/1871527322666230609141519"},{"key":"e_1_2_11_53_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.isci.2025.112825"},{"key":"e_1_2_11_54_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41531-025-01156-z"},{"key":"e_1_2_11_55_1","doi-asserted-by":"publisher","DOI":"10.1155\/jt\/5752904"},{"key":"e_1_2_11_56_1","doi-asserted-by":"publisher","DOI":"10.3390\/antiox13030326"},{"issue":"5","key":"e_1_2_11_57_1","first-page":"3227","article-title":"PM2.5 Induces Apoptosis, Oxidative Stress Injury and Melanin Metabolic Disorder in Human Melanocytes","volume":"19","author":"Suo D.","year":"2020","journal-title":"Experimental and Therapeutic Medicine"},{"key":"e_1_2_11_58_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms252413527"},{"key":"e_1_2_11_59_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.redox.2026.104239"},{"key":"e_1_2_11_60_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnagi.2022.885500"},{"key":"e_1_2_11_61_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2025.114764"},{"key":"e_1_2_11_62_1","doi-asserted-by":"publisher","DOI":"10.1016\/bs.apcsb.2023.02.014"},{"issue":"1","key":"e_1_2_11_63_1","first-page":"3","article-title":"Mitochondrial Electron Transport Chain, Ros Generation and Uncoupling (Review)","volume":"44","author":"Zhao R. Z.","year":"2019","journal-title":"International Journal of Molecular Medicine"},{"key":"e_1_2_11_64_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2025.05.021"},{"key":"e_1_2_11_65_1","doi-asserted-by":"publisher","DOI":"10.3390\/cells10113022"},{"key":"e_1_2_11_66_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41556-024-01513-9"},{"key":"e_1_2_11_67_1","doi-asserted-by":"publisher","DOI":"10.1038\/s44318-025-00604-z"},{"key":"e_1_2_11_68_1","doi-asserted-by":"publisher","DOI":"10.24272\/j.issn.2095-8137.2022.406"},{"key":"e_1_2_11_69_1","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.aah4066"},{"key":"e_1_2_11_70_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mam.2020.100889"},{"key":"e_1_2_11_71_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tiv.2022.105522"},{"key":"e_1_2_11_72_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-021-22979-3"},{"key":"e_1_2_11_73_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2023.109698"},{"key":"e_1_2_11_74_1","doi-asserted-by":"publisher","DOI":"10.1002\/brb3.2784"},{"key":"e_1_2_11_75_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2024.33602"},{"key":"e_1_2_11_76_1","doi-asserted-by":"publisher","DOI":"10.1002\/alz.14320"},{"key":"e_1_2_11_77_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ecoenv.2022.113664"},{"key":"e_1_2_11_78_1","doi-asserted-by":"publisher","DOI":"10.1093\/toxsci\/kfaf140"},{"key":"e_1_2_11_79_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11481-024-10101-5"},{"key":"e_1_2_11_80_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.3c08506"},{"key":"e_1_2_11_81_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ecoenv.2024.116386"},{"key":"e_1_2_11_82_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2021.09.014"},{"key":"e_1_2_11_83_1","doi-asserted-by":"publisher","DOI":"10.1155\/2022\/1837278"},{"key":"e_1_2_11_84_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-025-89422-1"},{"key":"e_1_2_11_85_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nbd.2013.08.003"},{"key":"e_1_2_11_86_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.4c00237"},{"key":"e_1_2_11_87_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2023.110520"},{"key":"e_1_2_11_88_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tiv.2018.07.004"},{"key":"e_1_2_11_89_1","first-page":"35","article-title":"Alpha\u2010Synuclein Aggregation in Parkinson's Disease","volume":"146","author":"Silva I. J. S. D.","year":"2025","journal-title":"Advances in protein chemistry and structural biology"},{"key":"e_1_2_11_90_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuint.2024.105880"},{"key":"e_1_2_11_91_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.29181"},{"key":"e_1_2_11_92_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmb.2022.167680"},{"key":"e_1_2_11_93_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-025-15991-w"},{"key":"e_1_2_11_94_1","doi-asserted-by":"publisher","DOI":"10.3390\/cells11050851"},{"issue":"35","key":"e_1_2_11_95_1","first-page":"7479","article-title":"Monoamine Oxidase\u2010B Inhibition Facilitates \u03b1\u2010Synuclein Secretion In Vitro and Delays Its Aggregation in rAAV\u2010Based Rat Models of Parkinson's Disease","volume":"41","author":"Nakamura Y.","year":"2021","journal-title":"Journal of Neuroscience: The Official Journal of the Society for Neuroscience"},{"key":"e_1_2_11_96_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jenvman.2024.121644"},{"key":"e_1_2_11_97_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chembiol.2021.04.003"},{"key":"e_1_2_11_98_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41421-020-0167-x"},{"key":"e_1_2_11_99_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms27010366"},{"key":"e_1_2_11_100_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tcb.2025.02.007"},{"key":"e_1_2_11_101_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41580-024-00757-5"},{"key":"e_1_2_11_102_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cbi.2025.111452"},{"key":"e_1_2_11_103_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.lfs.2025.123688"},{"key":"e_1_2_11_104_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10565-024-09910-4"},{"key":"e_1_2_11_105_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules25061441"},{"key":"e_1_2_11_106_1","doi-asserted-by":"publisher","DOI":"10.1155\/2023\/7389508"},{"key":"e_1_2_11_107_1","doi-asserted-by":"publisher","DOI":"10.3109\/10715762.2012.663084"},{"key":"e_1_2_11_108_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2020.562813"},{"key":"e_1_2_11_109_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13237-021-00367-y"},{"key":"e_1_2_11_110_1","doi-asserted-by":"publisher","DOI":"10.3390\/toxics13030151"},{"key":"e_1_2_11_111_1","doi-asserted-by":"publisher","DOI":"10.2147\/DNND.S482018"},{"key":"e_1_2_11_112_1","doi-asserted-by":"publisher","DOI":"10.3390\/medicina60010110"},{"key":"e_1_2_11_113_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.envpol.2025.126194"},{"key":"e_1_2_11_114_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molimm.2024.12.005"},{"key":"e_1_2_11_115_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neulet.2018.05.009"},{"key":"e_1_2_11_116_1","doi-asserted-by":"publisher","DOI":"10.1124\/mol.110.066837"},{"key":"e_1_2_11_117_1","doi-asserted-by":"publisher","DOI":"10.1093\/toxsci\/kfaa066"},{"key":"e_1_2_11_118_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms23010090"},{"key":"e_1_2_11_119_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11356-021-16056-x"},{"key":"e_1_2_11_120_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12013-024-01587-0"},{"key":"e_1_2_11_121_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2024.114222"},{"key":"e_1_2_11_122_1","doi-asserted-by":"publisher","DOI":"10.1002\/mco2.292"},{"key":"e_1_2_11_123_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tox.2021.152770"},{"key":"e_1_2_11_124_1","doi-asserted-by":"publisher","DOI":"10.15252\/embr.202051803"},{"key":"e_1_2_11_125_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhazmat.2024.134691"},{"key":"e_1_2_11_126_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.5c00751"},{"key":"e_1_2_11_127_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00204-023-03562-9"},{"key":"e_1_2_11_128_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41392-025-02253-4"},{"key":"e_1_2_11_129_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhazmat.2023.131827"},{"key":"e_1_2_11_130_1","doi-asserted-by":"publisher","DOI":"10.3390\/antiox14111316"},{"key":"e_1_2_11_131_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tibs.2020.11.007"},{"key":"e_1_2_11_132_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41419-023-06251-8"},{"key":"e_1_2_11_133_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.arr.2022.101817"},{"key":"e_1_2_11_134_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41593-022-01061-1"},{"key":"e_1_2_11_135_1","doi-asserted-by":"publisher","DOI":"10.4014\/jmb.2403.03029"},{"key":"e_1_2_11_136_1","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2025.1581109"},{"key":"e_1_2_11_137_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41577-022-00684-6"},{"key":"e_1_2_11_138_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2024.174450"},{"key":"e_1_2_11_139_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neulet.2021.136265"},{"key":"e_1_2_11_140_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12989-021-00433-y"},{"key":"e_1_2_11_141_1","doi-asserted-by":"publisher","DOI":"10.3389\/ftox.2024.1523387"},{"key":"e_1_2_11_142_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuro.2022.10.011"},{"key":"e_1_2_11_143_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.envres.2023.116267"},{"key":"e_1_2_11_144_1","doi-asserted-by":"publisher","DOI":"10.1289\/EHP134"},{"key":"e_1_2_11_145_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12640-019-00092-0"},{"key":"e_1_2_11_146_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anireprosci.2022.106924"},{"key":"e_1_2_11_147_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.28922"},{"key":"e_1_2_11_148_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.30067"},{"key":"e_1_2_11_149_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaneurol.2021.1335"},{"key":"e_1_2_11_150_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12889-025-22641-3"},{"key":"e_1_2_11_151_1","doi-asserted-by":"publisher","DOI":"10.1021\/envhealth.5c00336"},{"key":"e_1_2_11_152_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.28608"},{"key":"e_1_2_11_153_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.envres.2020.110105"},{"key":"e_1_2_11_154_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuro.2023.03.006"},{"key":"e_1_2_11_155_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.semnuclmed.2025.06.004"},{"key":"e_1_2_11_156_1","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.abo1997"},{"key":"e_1_2_11_157_1","doi-asserted-by":"publisher","DOI":"10.3390\/biomedicines13092183"},{"key":"e_1_2_11_158_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.expneurol.2021.113619"},{"key":"e_1_2_11_159_1","doi-asserted-by":"publisher","DOI":"10.3389\/fncir.2024.1453958"},{"key":"e_1_2_11_160_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joim.2021.03.007"},{"key":"e_1_2_11_161_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neulet.2019.134438"},{"key":"e_1_2_11_162_1","doi-asserted-by":"publisher","DOI":"10.1111\/cns.14607"},{"key":"e_1_2_11_163_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms232113224"},{"key":"e_1_2_11_164_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuint.2013.05.010"},{"key":"e_1_2_11_165_1","doi-asserted-by":"publisher","DOI":"10.1111\/cns.70586"},{"key":"e_1_2_11_166_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2024.02.023"},{"key":"e_1_2_11_167_1","doi-asserted-by":"publisher","DOI":"10.1080\/00207454.2022.2074848"},{"key":"e_1_2_11_168_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-031-11454-0_17"},{"key":"e_1_2_11_169_1","doi-asserted-by":"publisher","DOI":"10.1038\/jhg.2013.65"},{"key":"e_1_2_11_170_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2010.02.139"},{"key":"e_1_2_11_171_1","doi-asserted-by":"publisher","DOI":"10.3390\/ncrna9020027"},{"key":"e_1_2_11_172_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms252313007"},{"key":"e_1_2_11_173_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.2009.05175.x"},{"key":"e_1_2_11_174_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.arr.2024.102324"},{"key":"e_1_2_11_175_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-023-41105-z"},{"key":"e_1_2_11_176_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11356-022-20248-4"},{"key":"e_1_2_11_177_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-publhealth-052120-103607"},{"key":"e_1_2_11_178_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-024-80185-9"},{"key":"e_1_2_11_179_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuro.2025.103375"}],"container-title":["Journal of Biochemical and Molecular Toxicology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jbt.71089","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/jbt.71089","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jbt.71089","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T08:43:12Z","timestamp":1789548192000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jbt.71089"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,26]]},"references-count":178,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2026,9]]}},"alternative-id":["10.1002\/jbt.71089"],"URL":"https:\/\/doi.org\/10.1002\/jbt.71089","archive":["Portico"],"relation":{},"ISSN":["1095-6670","1099-0461"],"issn-type":[{"value":"1095-6670","type":"print"},{"value":"1099-0461","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8,26]]},"assertion":[{"value":"2026-04-29","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-08-19","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-08-26","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e71089"}}