{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,23]],"date-time":"2025-09-23T13:27:01Z","timestamp":1758634021406},"reference-count":84,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2014,5,27]],"date-time":"2014-05-27T00:00:00Z","timestamp":1401148800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Clinical Apheresis"],"published-print":{"date-parts":[[2014,8]]},"abstract":"<jats:p>Apheresis is an important treatment modality for the removal of pathologic antibodies and circulating proteins in kidney transplantation. The use of apheresis has been shown to be a necessary preconditioning component in ABO incompatible kidney transplant. Removal of pathologic anti\u2010A and anti\u2010B antibodies has been accomplished with a variety of apheresis modalities including plasma exchange, fractional plasma exchange, and immunoaborption techniques. Using these modalities in conjunction with potent modern immunosuppression, ABO incompatible kidney transplants have achieved graft and patient survivals similar to that seen in ABO compatible transplants. Apheresis has also been an important modality in the removal of anti\u2010human leukocyte antigen (HLA) antibodies both for the purposes of desensitization and treatment of antibody mediated rejection of the kidney. Although good randomized controlled trials are lacking in the treatment of acute antibody mediated rejection, most treatment regimens include the use of apheresis as an essential component for reduction of anti\u2010HLA antibody titers. Similarly, a variety of desensitization protocols have been developed to allow highly sensitized kidney transplant candidates to be successfully transplanted in the presence of donor\u2010specific HLA antibodies. Most of these protocols involve apheresis to improve the removal of pathologic antibodies. Finally, aphereis has been used with mixed success for the treatment of recurrent focal segmental glomerulosclerosis. Evidence indicates that in some cases a circulating factor exists which apheresis can remove and ameliorate the nephrotic proteinuria. J. Clin. Apheresis 29:206\u2013210, 2014. \u00a9 2014 Wiley Periodicals, Inc.<\/jats:p>","DOI":"10.1002\/jca.21330","type":"journal-article","created":{"date-parts":[[2014,5,27]],"date-time":"2014-05-27T11:18:07Z","timestamp":1401189487000},"page":"206-210","source":"Crossref","is-referenced-by-count":7,"title":["Therapeutic apheresis in renal transplantation; current practices"],"prefix":"10.1002","volume":"29","author":[{"given":"Douglas S.","family":"Keith","sequence":"first","affiliation":[{"name":"Division of Nephrology University of Virginia Medical Center Charlottesville Virginia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,5,27]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2005.01031.x"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2011.03464.x"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.TP.0000078622.43689.D4"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.tp.0000296103.34735.b8"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1537-2995.2008.01857.x"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/jca.20153"},{"key":"e_1_2_8_8_1","first-page":"557","article-title":"Comparative evaluation of immunoadsorption and double filtration plasmapheresis for removal of anti\u2010A or \u2010B antibody in ABO\u2010incompatible kidney transplantation. japanese biosynsorb research group","volume":"24","author":"Agishi T","year":"1992","journal-title":"Transplant Proc"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/jca.21201"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.tp.0000296007.08413.75"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-3089.2006.00292.x"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0b013e318245b2af"},{"key":"e_1_2_8_13_1","first-page":"21","article-title":"Desensitization and crossmatch conversion in deceased donor kidney transplantation","volume":"63","author":"Bartel G","year":"2011","journal-title":"Minerva Urol Nefrol"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/MOT.0b013e32834c23ba"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/jca.20297"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/MOT.0b013e32834897c1"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0b013e31821c93bb"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2010.03226.x"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0b013e3181ea3985"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.transproceed.2010.09.043"},{"key":"e_1_2_8_21_1","first-page":"130","article-title":"Kidney transplant in highly sensitized patients after desensitization with plasmapheresis and low\u2010dose intravenous immunoglobulin","volume":"8","author":"Yuan XP","year":"2010","journal-title":"Exp Clin Transplant"},{"key":"e_1_2_8_22_1","first-page":"369","article-title":"Desensitization and renal transplant: Plasmapheresis\/IVIG standard dose in patients with high immunological risk","volume":"77","author":"Flores\u2010Gama F","year":"2009","journal-title":"Cir Cir"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1159\/000178979"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.3346\/jkms.2009.24.S1.S143"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0b013e3181919a16"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1080\/08860220903001861"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.05321107"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0b013e318176ae2c"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2006.01393.x"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.transproceed.2004.12.063"},{"key":"e_1_2_8_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0041-1345(02)03044-0"},{"key":"e_1_2_8_32_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-200009270-00006"},{"key":"e_1_2_8_33_1","doi-asserted-by":"publisher","DOI":"10.1177\/039139889702000110"},{"key":"e_1_2_8_34_1","first-page":"3448","article-title":"Pretransplantation plasmapheresis in HLA\u2010sensitized patients: Five years experience","volume":"27","author":"Alarabi A","year":"1995","journal-title":"Transplant Proc"},{"key":"e_1_2_8_35_1","first-page":"1040","article-title":"Beneficial effects of double\u2010filtration plasmapheresis on living related donor renal transplantation in presensitized recipients","volume":"27","author":"Miura S","year":"1995","journal-title":"Transplant Proc"},{"key":"e_1_2_8_36_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1012376"},{"key":"e_1_2_8_37_1","doi-asserted-by":"publisher","DOI":"10.1002\/jca.21211"},{"key":"e_1_2_8_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.smim.2011.08.015"},{"key":"e_1_2_8_39_1","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0b013e31825d1587"},{"key":"e_1_2_8_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.transproceed.2011.03.023"},{"key":"e_1_2_8_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.transproceed.2010.07.068"},{"key":"e_1_2_8_42_1","doi-asserted-by":"publisher","DOI":"10.1097\/MOT.0b013e3283342712"},{"key":"e_1_2_8_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.transproceed.2009.06.197"},{"key":"e_1_2_8_44_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.transproceed.2009.01.062"},{"key":"e_1_2_8_45_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2009.02591.x"},{"key":"e_1_2_8_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.trre.2008.08.004"},{"key":"e_1_2_8_47_1","doi-asserted-by":"publisher","DOI":"10.1517\/13543784.16.5.625"},{"key":"e_1_2_8_48_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.TP.0000122187.76518.BC"},{"key":"e_1_2_8_49_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.TP.0000128194.55934.48"},{"key":"e_1_2_8_50_1","doi-asserted-by":"publisher","DOI":"10.1002\/jca.10062"},{"key":"e_1_2_8_51_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.transproceed.2003.09.029"},{"key":"e_1_2_8_52_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1526-0968.2003.00101.x"},{"key":"e_1_2_8_53_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.TP.0000060252.57111.AC"},{"key":"e_1_2_8_54_1","doi-asserted-by":"publisher","DOI":"10.1097\/00042307-200203000-00003"},{"key":"e_1_2_8_55_1","doi-asserted-by":"publisher","DOI":"10.1002\/1098-1101(2000)15:3<180::AID-JCA5>3.0.CO;2-6"},{"key":"e_1_2_8_56_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0041-1345(96)00636-7"},{"key":"e_1_2_8_57_1","first-page":"934","article-title":"Treatment of acute humoral rejection in kidney transplantation with plasmapheresis","volume":"27","author":"Grandtnerova B","year":"1995","journal-title":"Transplant Proc"},{"key":"e_1_2_8_58_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1432-2277.1992.tb01743.x"},{"key":"e_1_2_8_59_1","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/S0022-5347(17)50170-6","article-title":"Plasmapheresis\u2010\u2010adjunctive treatment for steroid\u2010resistant rejection in renal transplantation","volume":"131","author":"Banowsky LH","year":"1984","journal-title":"J Urol"},{"key":"e_1_2_8_60_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2006.01613.x"},{"key":"e_1_2_8_61_1","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1681\/ASN.V103552","article-title":"\u201cThe FSGS factor:\u201d enrichment and in vivo effect of activity from focal segmental glomerulosclerosis plasma","volume":"10","author":"Sharma M","year":"1999","journal-title":"J Am Soc Nephrol"},{"key":"e_1_2_8_62_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-139X.2011.01031.x"},{"key":"e_1_2_8_63_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1594.2010.01068.x"},{"key":"e_1_2_8_64_1","doi-asserted-by":"publisher","DOI":"10.5414\/CNP74173"},{"key":"e_1_2_8_65_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.transproceed.2009.06.044"},{"key":"e_1_2_8_66_1","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfm616"},{"key":"e_1_2_8_67_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1432-2277.2006.00395.x"},{"key":"e_1_2_8_68_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-3046.2006.00571.x"},{"key":"e_1_2_8_69_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2006.08.637"},{"key":"e_1_2_8_70_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2005.01112.x"},{"key":"e_1_2_8_71_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00467-005-1858-0"},{"key":"e_1_2_8_72_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.transproceed.2005.02.061"},{"key":"e_1_2_8_73_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-0968.2004.00164.x"},{"key":"e_1_2_8_74_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00467-003-1208-z"},{"key":"e_1_2_8_75_1","doi-asserted-by":"publisher","DOI":"10.1007\/s004670100008"},{"key":"e_1_2_8_76_1","first-page":"271","article-title":"Plasmapheresis treatment of recurrent FSGS in adult renal transplant recipients","volume":"56","author":"Matalon A","year":"2001","journal-title":"Clin Nephrol"},{"key":"e_1_2_8_77_1","doi-asserted-by":"publisher","DOI":"10.1002\/jca.10007"},{"key":"e_1_2_8_78_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1755.2001.00759.x"},{"key":"e_1_2_8_79_1","doi-asserted-by":"publisher","DOI":"10.1007\/s004670000378"},{"key":"e_1_2_8_80_1","first-page":"347","article-title":"Apheresis in primary focal segmental glomerulosclerosis of native and transplanted kidneys: A therapeutic protocol","volume":"13","author":"Moriconi L","year":"2000","journal-title":"J Nephrol"},{"key":"e_1_2_8_81_1","doi-asserted-by":"publisher","DOI":"10.1177\/039139880002301203"},{"key":"e_1_2_8_82_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0272-6386(99)70010-7"},{"key":"e_1_2_8_83_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1744-9987.1997.tb00040.x"},{"key":"e_1_2_8_84_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0272-6386(12)80381-7"},{"key":"e_1_2_8_85_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00869127"}],"container-title":["Journal of Clinical Apheresis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjca.21330","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jca.21330","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,12]],"date-time":"2023-09-12T04:04:49Z","timestamp":1694491489000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jca.21330"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,5,27]]},"references-count":84,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2014,8]]}},"alternative-id":["10.1002\/jca.21330"],"URL":"https:\/\/doi.org\/10.1002\/jca.21330","archive":["Portico"],"relation":{},"ISSN":["0733-2459","1098-1101"],"issn-type":[{"value":"0733-2459","type":"print"},{"value":"1098-1101","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,5,27]]}}}