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We report a case of HE treated by plasma exchange where no clinical or neurophysiologic improvement was observed despite documented reduction of the anti\u2010TPO antibody to levels below the limits of laboratory detection. We discuss these findings in the context of the known literature for this disease process. J. Clin. Apheresis 30:188\u2013192, 2015. \u00a9 2014 Wiley Periodicals, Inc.<\/jats:p>","DOI":"10.1002\/jca.21353","type":"journal-article","created":{"date-parts":[[2014,8,12]],"date-time":"2014-08-12T15:38:39Z","timestamp":1407857919000},"page":"188-192","source":"Crossref","is-referenced-by-count":33,"title":["The use of plasma exchange in <scp>H<\/scp>ashimoto's encephalopathy: A case report and review of the literature"],"prefix":"10.1002","volume":"30","author":[{"given":"Melissa K.","family":"Cook","sequence":"first","affiliation":[{"name":"Department of Neurology Medical College of Wisconsin Milwaukee Wisconsin"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark","family":"Malkin","sequence":"additional","affiliation":[{"name":"Department of Neurology Virginia Commonwealth University Richmond Virginia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew S.","family":"Karafin","sequence":"additional","affiliation":[{"name":"Medical Sciences 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