{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,9,26]],"date-time":"2023-09-26T14:51:23Z","timestamp":1695739883621},"reference-count":10,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2015,8,31]],"date-time":"2015-08-31T00:00:00Z","timestamp":1440979200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Clinical Apheresis"],"published-print":{"date-parts":[[2016,10]]},"abstract":"<jats:p>Some patients with multiple sclerosis (MS) are resistant to steroid therapy. In them an alternative therapy could be therapeutic apheresis (TA). A woman with relapsing\u2010remitting cerebral MS with dizziness and imbalance, resistant to steroid therapy was treated with low volume plasmapheresis with saline substitution. The first four sessions were performed every other day, 5\u2010th after 30 days, 6\u2010th 3 months later, and 7\u2010th 6 months later. During each session 1000\u20101500 ml plasma was substituted with saline solution only. Symptoms were reduced. Objective vestibular and ocular\u2010motor tests prior to and after the TA demonstrated improved function. In conclusion, low volume plasmapheresis with saline substitution might be effective therapeutic option for steroid resistant MS. Objective methods of measuring vestibular and ocular\u2010motor functions are useful in assessing MS treatment. J. Clin. Apheresis 31:470\u2013472, 2016. \u00a9 2015 Wiley Periodicals, Inc.<\/jats:p>","DOI":"10.1002\/jca.21418","type":"journal-article","created":{"date-parts":[[2015,9,2]],"date-time":"2015-09-02T15:14:28Z","timestamp":1441206868000},"page":"470-472","source":"Crossref","is-referenced-by-count":3,"title":["Vestibular and ocular motor function prior to and after therapeutic apheresis with small plasmafilter in multiple sclerosis"],"prefix":"10.1002","volume":"31","author":[{"given":"Ognyan I.","family":"Kolev","sequence":"first","affiliation":[{"name":"University Hospital of Neurology and Psychiatry \u201cSt. Naum\u201d Sofia Bulgaria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Plamen","family":"Kenarov","sequence":"additional","affiliation":[{"name":"Department of Neuroreanimation Medical University \u2010 Sofia Sofia Bulgaria"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,8,31]]},"reference":[{"key":"e_1_2_3_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/1531-8249(199912)46:6<878::AID-ANA10>3.0.CO;2-Q"},{"key":"e_1_2_3_3_1","doi-asserted-by":"publisher","DOI":"10.1212\/01.WNL.0000138437.99046.6B"},{"key":"e_1_2_3_4_1","doi-asserted-by":"publisher","DOI":"10.1159\/000224630"},{"key":"e_1_2_3_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-008-0061-1"},{"key":"e_1_2_3_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(05)67102-4"},{"key":"e_1_2_3_7_1","doi-asserted-by":"publisher","DOI":"10.1186\/1742-2094-9-80"},{"key":"e_1_2_3_8_1","doi-asserted-by":"publisher","DOI":"10.1159\/000332397"},{"key":"e_1_2_3_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2249.2011.04547.x"},{"key":"e_1_2_3_10_1","doi-asserted-by":"publisher","DOI":"10.1515\/REVNEURO.2009.20.2.133"},{"key":"e_1_2_3_11_1","doi-asserted-by":"publisher","DOI":"10.1186\/1479-5876-10-239"}],"container-title":["Journal of Clinical Apheresis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjca.21418","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jca.21418","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,24]],"date-time":"2023-09-24T11:46:53Z","timestamp":1695556013000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jca.21418"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,8,31]]},"references-count":10,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2016,10]]}},"alternative-id":["10.1002\/jca.21418"],"URL":"https:\/\/doi.org\/10.1002\/jca.21418","archive":["Portico"],"relation":{},"ISSN":["0733-2459","1098-1101"],"issn-type":[{"value":"0733-2459","type":"print"},{"value":"1098-1101","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,8,31]]}}}