{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,11,19]],"date-time":"2024-11-19T17:07:11Z","timestamp":1732036031693},"reference-count":4,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2016,4,26]],"date-time":"2016-04-26T00:00:00Z","timestamp":1461628800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Clinical Apheresis"],"published-print":{"date-parts":[[2017,2]]},"abstract":"<jats:sec><jats:title>Purpose<\/jats:title><jats:p>A red cell exchange was performed to prevent a potentially fatal hemolytic transfusion reaction in a patient with anti\u2010e who was transfused with e\u2010antigen unscreened red blood cells during liver transplant surgery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Case Report<\/jats:title><jats:p>A 64\u2010year\u2010old woman with cirrhosis due to hepatitis C was scheduled to receive a liver transplant. She had a previously documented anti\u2010e, an antibody to the Rh(e)\u2010antigen that is known to cause delayed hemolytic transfusion reactions. Pre\u2010operatively and intra\u2010operatively, she had massive hemorrhage which required transfusion of 34 e\u2010antigen unscreened red blood cells (RBCs) most of which were incompatible. The hemoglobin dropped from 9.1 g\/dL on post\u2010operative day (POD)1 to 6.6 g\/dL on POD6, with no evidence of blood loss. The bilirubin also increased from 5.0 mg\/dL on POD 1 to 11.0 mg\/dL on POD 6. As she was also becoming more hemodynamically unstable, a red cell exchange with 10 units of e\u2010negative RBCs was performed on POD 6. She improved clinically and was extubated the following day. A few residual transfused e\u2010positive red cells were detected after the red cell exchange until POD 13.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This case illustrates how a red cell exchange can mitigate the potentially harmful effects of a delayed hemolytic transfusion reaction caused by red cell antibodies. With massive intraoperative blood loss it may not be possible to have antigen\u2010negative RBCs immediately available, particularly for the e\u2010antigen, which is present in 98% of the donor population. The ability to perform such a procedure may be life\u2010saving in such patients. J. Clin. Apheresis 32:59\u201361, 2017. \u00a9 2016 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jca.21461","type":"journal-article","created":{"date-parts":[[2016,4,26]],"date-time":"2016-04-26T23:19:32Z","timestamp":1461712772000},"page":"59-61","source":"Crossref","is-referenced-by-count":6,"title":["Red cell exchange to mitigate a delayed hemolytic transfusion reaction in a patient transfused with incompatible red blood cells"],"prefix":"10.1002","volume":"32","author":[{"given":"Mehraboon S.","family":"Irani","sequence":"first","affiliation":[{"name":"Therapeutic Services, Blood Center of Wisconsin Milwaukee Wisconsin"},{"name":"Transfusion Services, Aurora Health Care Milwaukee Wisconsin"},{"name":"Medical College of Wisconsin Milwaukee Wisconsin"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthew S.","family":"Karafin","sequence":"additional","affiliation":[{"name":"Medical College of Wisconsin Milwaukee Wisconsin"},{"name":"Medical Sciences Institute, Blood Center of Wisconsin Milwaukee Wisconsin"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luke","family":"Ernster","sequence":"additional","affiliation":[{"name":"Transfusion Service, ACL Laboratories and Aurora Health Care, St. Luke's Medical Center Milwaukee Wisconsin"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,4,26]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/jca.21276"},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.5858\/arpa.2012-0154-CR"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/jca.20225"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1537-2995.1993.33693296819.x"}],"container-title":["Journal of Clinical Apheresis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjca.21461","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjca.21461","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jca.21461","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,24]],"date-time":"2023-09-24T00:06:22Z","timestamp":1695513982000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jca.21461"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,4,26]]},"references-count":4,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017,2]]}},"alternative-id":["10.1002\/jca.21461"],"URL":"https:\/\/doi.org\/10.1002\/jca.21461","archive":["Portico"],"relation":{},"ISSN":["0733-2459","1098-1101"],"issn-type":[{"value":"0733-2459","type":"print"},{"value":"1098-1101","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,4,26]]}}}