{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T14:47:03Z","timestamp":1761490023633},"reference-count":8,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2016,6,15]],"date-time":"2016-06-15T00:00:00Z","timestamp":1465948800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Clinical Apheresis"],"published-print":{"date-parts":[[2017,6]]},"abstract":"<jats:p>Apheresis has been used to lower the parasite burden of patients with <jats:italic>Loa loa<\/jats:italic> infection, but there are no reports regarding how to do this using modern, continuous flow equipment with a currently available program. A 23\u2010year\u2010old female refugee from Cameroon with known <jats:italic>Loa loa<\/jats:italic> infection presented to our Emergency Department with acute mental status changes and a picture of encephalitis. Lumbar puncture revealed <jats:italic>Loa loa<\/jats:italic> in her cerebrospinal fluid. Her midday blood microfilaria count was 15,000\/mL. Because treatment with diethylcarbamazine was under consideration, we were asked to lower her parasite burden using apheresis. One single 2\u2010total blood volume apheresis using the mononuclear cell program (without hydroxyethyl starch) on a COBE<jats:sup>\u00ae<\/jats:sup> Spectra Apheresis System decreased the microfilarial load from 15,000\/mL to 10,666\/mL, a 29% reduction. J. Clin. Apheresis 32:200\u2013202, 2017. \u00a9 2016 Wiley Periodicals, Inc.<\/jats:p>","DOI":"10.1002\/jca.21479","type":"journal-article","created":{"date-parts":[[2016,6,15]],"date-time":"2016-06-15T17:09:16Z","timestamp":1466010556000},"page":"200-202","source":"Crossref","is-referenced-by-count":4,"title":["Therapeutic apheresis using a mononuclear cell program to lower the microfilaria burden of a 23\u2010year\u2010old African woman with loiasis"],"prefix":"10.1002","volume":"32","author":[{"given":"Yong","family":"Zhao","sequence":"first","affiliation":[{"name":"Transfusion Medicine and Apheresis Service UMass Memorial Medical Center Worcester Massachusetts"},{"name":"Division of Transfusion Medicine UMass Memorial Medical Center Worcester Massachusetts"},{"name":"Department of Medicine University of Massachusetts Medical School Worcester Massachusetts"},{"name":"Department of Pathology University of Massachusetts Medical School Worcester Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brian","family":"Alexander","sequence":"additional","affiliation":[{"name":"Transfusion Medicine and Apheresis Service UMass Memorial Medical Center Worcester Massachusetts"},{"name":"Department of Anesthesiology University of Massachusetts Medical School Worcester Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeffrey A.","family":"Bailey","sequence":"additional","affiliation":[{"name":"Transfusion Medicine and Apheresis Service UMass Memorial Medical Center Worcester Massachusetts"},{"name":"Division of Transfusion Medicine UMass Memorial Medical Center Worcester Massachusetts"},{"name":"Department of Medicine University of Massachusetts Medical School Worcester Massachusetts"},{"name":"Department of Pathology University of Massachusetts Medical School Worcester Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Linda","family":"Welch","sequence":"additional","affiliation":[{"name":"Transfusion Medicine and Apheresis Service UMass Memorial Medical Center Worcester Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mindy","family":"Greene","sequence":"additional","affiliation":[{"name":"Transfusion Medicine and Apheresis Service UMass Memorial Medical Center Worcester Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michelle","family":"Vauthrin","sequence":"additional","affiliation":[{"name":"Transfusion Medicine and Apheresis Service UMass Memorial Medical Center Worcester Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Mitchell","sequence":"additional","affiliation":[{"name":"Department of Pathology University of Massachusetts Medical School Worcester Massachusetts"},{"name":"Division of Laboratory Medicine (Microbiology) UMass Memorial Medical Center Worcester Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert","family":"Weinstein","sequence":"additional","affiliation":[{"name":"Transfusion Medicine and Apheresis Service UMass Memorial Medical Center Worcester Massachusetts"},{"name":"Division of Transfusion Medicine UMass Memorial Medical Center Worcester Massachusetts"},{"name":"Department of Medicine University of Massachusetts Medical School Worcester Massachusetts"},{"name":"Department of Pathology University of Massachusetts Medical School Worcester Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,6,15]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1708-8305.2007.00166.x"},{"key":"e_1_2_5_3_1","unstructured":"Centers for Disease Control and Prevention Website. 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