{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T16:05:46Z","timestamp":1792253146755,"version":"4.4.0"},"reference-count":22,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2016,7,21]],"date-time":"2016-07-21T00:00:00Z","timestamp":1469059200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Clinical Apheresis"],"published-print":{"date-parts":[[2017,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Although many apheresis centers offer extracorporeal photopheresis (ECP), little is known about current treatment practices.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>An electronic survey was distributed to assess ECP practice internationally.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of 251 responses, 137 met criteria for analysis. Most respondents were from North America (80%). Nurses perform ECP at most centers (84%) and the majority of centers treat adults only (52%). Most centers treat fewer than 50 patients\/year (83%) and perform fewer than 300 procedures\/year (70%). Closed system devices (XTS and\/or Cellex) are used to perform ECP at most centers (96%). The most common indications for ECP are acute\/chronic skin graft versus host disease (89%) and cutaneous T\u2010cell lymphoma (63%). The typical wait time for ECP treatment is less than 2 weeks (91%). Most centers do not routinely perform quality control assessment of the collected product (66%). There are device\u2010specific differences in treatment parameters. For example, XTS users more frequently have a minimum weight limit (<jats:italic>P<\/jats:italic>\u2009=\u20090.003) and use laboratory parameters to determine eligibility for treatment (<jats:italic>P<\/jats:italic>\u2009=\u20090.03). Regardless of device used, the majority of centers assess the clinical status of the patient before each procedure. Greater than 50% of respondents would defer treatment for hemodynamic instability due to active sepsis or heart failure, positive blood culture in the past 24 h or current fever.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This survey based study describes current ECP practices. Further research to provide evidence for optimal standardization of patient qualifications, procedure parameters and product quality assessment is recommended.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jca.21486","type":"journal-article","created":{"date-parts":[[2016,7,21]],"date-time":"2016-07-21T15:03:16Z","timestamp":1469113396000},"page":"215-223","source":"Crossref","is-referenced-by-count":38,"title":["Extracorporeal photopheresis practice patterns: An international survey by the ASFA ECP subcommittee"],"prefix":"10.1002","volume":"32","author":[{"given":"Nancy M.","family":"Dunbar","sequence":"first","affiliation":[{"name":"Department of Pathology and Laboratory Medicine Dartmouth\u2010Hitchcock Medical Center  Lebanon NH"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jay S.","family":"Raval","sequence":"additional","affiliation":[{"name":"Department of Pathology and Laboratory Medicine University of North Carolina Chapel Hill NC"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"Johnson","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine and Pathology University of Minnesota Minneapolis MN"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cori M.","family":"Abikoff","sequence":"additional","affiliation":[{"name":"Department of Pediatrics New York Medical College Valhalla NY"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jill","family":"Adamski","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine and Pathology, Mayo Clinic Phoenix AZ"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura L.","family":"Cooling","sequence":"additional","affiliation":[{"name":"Department of Pathology, University of Michigan School of Medicine Ann Arbor MI"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brenda","family":"Grossman","sequence":"additional","affiliation":[{"name":"Department of Pathology and Immunology, Washington University School of Medicine in St. Louis St. Louis MO"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haewon C.","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Pathology and Laboratory Medicine Children's Hospital of Philadelphia Philadelphia PA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marisa B.","family":"Marques","sequence":"additional","affiliation":[{"name":"Department of Pathology University of Alabama Birmingham AL"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shanna","family":"Morgan","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine and Pathology University of Minnesota Minneapolis MN"},{"name":"American Red Cross St. Paul MN"},{"name":"Veterans Affairs Medical Center Minneapolis MN"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amy E.","family":"Schmidt","sequence":"additional","affiliation":[{"name":"Department of Pathology and Laboratory Medicine University of Rochester Medical Center Rochester NY"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven R.","family":"Sloan","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine Boston Children's Hospital Boston MA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leon L.","family":"Su","sequence":"additional","affiliation":[{"name":"Department of Pathology and Laboratory Medicine Phoenix Children's Hospital Phoenix AZ"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zbigniew M.","family":"Szczepiorkowski","sequence":"additional","affiliation":[{"name":"Department of Pathology and Laboratory Medicine Dartmouth\u2010Hitchcock Medical Center  Lebanon NH"},{"name":"Institute of Hematology and Transfusion Medicine Warsaw Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F. 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