{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,20]],"date-time":"2026-02-20T22:10:38Z","timestamp":1771625438402,"version":"3.50.1"},"reference-count":18,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2017,9,18]],"date-time":"2017-09-18T00:00:00Z","timestamp":1505692800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Clinical Apheresis"],"published-print":{"date-parts":[[2018,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>Severe falciparum malaria is associated with multiple organ dysfunction and a high rate of fatal outcome. Malaria is a world\u2010wide disease in tropical areas through the bites of vector mosquitoes. Parasitic protozoans introduced by the mosquito's saliva to the blood travel to the liver then mature and reproduce. In humans, malaria is caused by <jats:italic>Plasmodium falciparum<\/jats:italic>, <jats:italic>P. malariae<\/jats:italic>, <jats:italic>P. ovale<\/jats:italic>, <jats:italic>P. vivax<\/jats:italic>, and <jats:italic>P. knowlesi,<\/jats:italic> and <jats:italic>P. falciparum<\/jats:italic> causes most deaths. Typical malaria symptoms include fever, chills, fatigue, headache, nausea, and vomiting. In severe cases, it can cause jaundice, seizures, coma, or death. Jaundice, caused by intravascular hemolysis is a usual complication of malaria, especially in patients with <jats:italic>P. falciparum<\/jats:italic> infection. The use of exchange transfusion in malaria is not currently advocated by the Centers of Disease Control and Prevention (CDC) of the United States of America. The role of therapeutic plasma exchange as an adjunctive therapy in malaria has not been widely discussed in the literature. Here, we present a 23\u2010year\u2010old patient with jaundice, acute renal failure, and cerebral involvement who was successfully treated with plasma exchange and hemodialysis.<\/jats:p>","DOI":"10.1002\/jca.21586","type":"journal-article","created":{"date-parts":[[2017,9,18]],"date-time":"2017-09-18T14:41:58Z","timestamp":1505745718000},"page":"419-422","source":"Crossref","is-referenced-by-count":7,"title":["Therapeutic plasma exchange in the treatment of complicated <i>Plasmodium falciparum<\/i> malaria: A case report"],"prefix":"10.1002","volume":"33","author":[{"given":"Tsong\u2010Yih","family":"Ou","sequence":"first","affiliation":[{"name":"Division of Infectious Disease, Department of Internal Medicine Wan\u2010Fang Hospital, Taipei Medical University Taipei Taiwan"},{"name":"Department of Internal Medicine, School of Medicine, College of Medicine Taipei Medical University Taipei Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cheng\u2010Yen","family":"Chuang","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine, Department of Internal Medicine Wan\u2010Fang Hospital, Taipei Medical University Taipei Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chun\u2010Da","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine Wan\u2010Fang Hospital, Taipei Medical University Taipei Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1816-7215","authenticated-orcid":false,"given":"Chung\u2010Yi","family":"Cheng","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, School of Medicine, College of Medicine Taipei Medical University Taipei Taiwan"},{"name":"Division of Nephrology, Department of Internal Medicine Wan\u2010Fang Hospital, Taipei Medical University Taipei Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,9,18]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph110605651"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1186\/cc2183"},{"key":"e_1_2_5_4_1","volume-title":"Guidelines for the Treatment of Malaria","author":"WHO","year":"2015"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01644550"},{"key":"e_1_2_5_6_1","first-page":"1212","article-title":"Guillain\u2010Barre's syndrome associated with Plasmodium falciparum malaria: role of plasma exchange","volume":"84","author":"Sithinamsuwan P","year":"2001","journal-title":"J Med Assoc Thai."},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.4103\/0971-4065.125054"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1160\/TH09-04-0223"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/jca.21291"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1038\/415673a"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.177.1.145"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1586\/eri.10.90"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198202113060601"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.1998.58.348"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1086\/339810"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1186\/1475-2875-6-138"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1182\/asheducation.V2012.1.7.3797920"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1186\/1475-2875-10-339"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12936-015-0874-1"}],"container-title":["Journal of Clinical Apheresis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjca.21586","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jca.21586","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,17]],"date-time":"2023-09-17T23:33:08Z","timestamp":1694993588000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jca.21586"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,9,18]]},"references-count":18,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2018,6]]}},"alternative-id":["10.1002\/jca.21586"],"URL":"https:\/\/doi.org\/10.1002\/jca.21586","archive":["Portico"],"relation":{},"ISSN":["0733-2459","1098-1101"],"issn-type":[{"value":"0733-2459","type":"print"},{"value":"1098-1101","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,9,18]]}}}