{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T20:01:14Z","timestamp":1790712074301,"version":"4.1.0"},"reference-count":22,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2006,11,14]],"date-time":"2006-11-14T00:00:00Z","timestamp":1163462400000},"content-version":"vor","delay-in-days":5431,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Clinical Apheresis"],"published-print":{"date-parts":[[1992,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Donor exposure can be strikingly reduced for patients with classical hemophilia A and von Willebrand's disease when large volumes of potent cryoprecipitated AHF are prepared from donors following DDAVP (1\u2010deamino\u20108\u2010D\u2010arginine vasopressin) stimulation and automated plasmapheresis\u2014a procedure called \u201cplasma exchange donation.\u201d Although this procedure has been reported to be relatively safe for donors, data are limited. Accordingly, we studied 20 donors during 48 procedures using DDAVP (0.3 \u03bcg\/kg IV) followed by 2\u20133 L plasma collection. Replacement fluid for each initial plasma exchange donation was plasma protein fraction; autologous cryoprecipitate\u2010poor plasma was used for subsequent procedures. Mild reactions, particularly facial flushing, were noted in all 48 procedures. No procedure was discontinued, but four were modified due to either an increased pulse rate (\u226420\/min from baseline) or a fall in systolic or diastolic blood pressure (\u226420 mm Hg from baseline). No donor was deferred or withdrew from the program. Based on our modest experience, DDAVP stimulated plasma exchange donation appears to be a safe and effective method for collecting large quantities of plasma from which potent cryoprecipitated AHF can be prepared. \u00a9 1992 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/jca.2920070208","type":"journal-article","created":{"date-parts":[[2007,2,21]],"date-time":"2007-02-21T15:42:44Z","timestamp":1172072564000},"page":"78-80","source":"Crossref","is-referenced-by-count":5,"title":["Donor reactions during DDAVP\u2010stimulated plasmapheresis"],"prefix":"10.1002","volume":"7","author":[{"given":"M. Joleen","family":"Randels","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ronald G.","family":"Strauss","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Delores","family":"Cordle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Theodore A. W.","family":"Koerner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alice S.","family":"Floss","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2006,11,14]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1537-2995.1988.28488265251.x"},{"key":"e_1_2_1_3_2","doi-asserted-by":"crossref","first-page":"2067","DOI":"10.1182\/blood.V73.8.2067.2067","article-title":"Levine PH factor concentrates for treatment of hemophilia: which one to blood","volume":"73","author":"Brettler DB","year":"1989","journal-title":"Blood"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.2830320207"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-106-1-35"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1537-2995.1989.29489242800.x"},{"key":"e_1_2_1_7_2","unstructured":"McLeodBC ColeER SassettiRJ PierceMI: Factors VIII collection by pheresis.Lancet2671\u2013673 1980."},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.252.19.2726"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-103-1-6"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/0049-3848(87)90170-8"},{"key":"e_1_2_1_11_2","doi-asserted-by":"crossref","first-page":"1449","DOI":"10.1182\/blood.V72.5.1449.1449","article-title":"Desmopressin: A nontransfusional form of treatment for congenital and acquired bleeding disorders","volume":"72","author":"Mannucci PM","year":"1988","journal-title":"Blood"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1537-2995.1988.28488265254.x"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/0049-3848(88)90328-3"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.2830280115"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.2830310310"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(90)92623-P"},{"key":"e_1_2_1_17_2","first-page":"1","volume-title":"Technical Manual","author":"Walker RH","year":"1990"},{"key":"e_1_2_1_18_2","first-page":"2","volume-title":"Standards for Blood Banks and Transfusion Services","author":"Holland PV","year":"1989"},{"key":"e_1_2_1_19_2","unstructured":"21 Code of Federal Regulations. Ch. 1 (4\u20131\u201390 edition) pp.122\u2013124."},{"key":"e_1_2_1_20_2","doi-asserted-by":"publisher","DOI":"10.1002\/jca.2920060105"},{"key":"e_1_2_1_21_2","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.2830320405"},{"key":"e_1_2_1_22_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198801143180215"},{"key":"e_1_2_1_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(84)80951-8"}],"container-title":["Journal of Clinical Apheresis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjca.2920070208","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jca.2920070208","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,23]],"date-time":"2023-10-23T11:50:18Z","timestamp":1698061818000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jca.2920070208"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1992,1]]},"references-count":22,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1992,1]]}},"alternative-id":["10.1002\/jca.2920070208"],"URL":"https:\/\/doi.org\/10.1002\/jca.2920070208","archive":["Portico"],"relation":{},"ISSN":["0733-2459","1098-1101"],"issn-type":[{"value":"0733-2459","type":"print"},{"value":"1098-1101","type":"electronic"}],"subject":[],"published":{"date-parts":[[1992,1]]}}}