{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,14]],"date-time":"2025-10-14T06:52:03Z","timestamp":1760424723944},"reference-count":34,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2006,6,1]],"date-time":"2006-06-01T00:00:00Z","timestamp":1149120000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Cellular Biochemistry"],"published-print":{"date-parts":[[2006,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The 24.5 kDa ribosomal protein L10 (RP\u2010L10), which was encoded by QM gene, was known to interact with the SH3 domain of Yes kinase. Herein, we demonstrate that RP\u2010L10 interacts with the SH3 domain of Src and activates the binding of the Nck1 adaptor protein with skeletal proteins such as the Wiskott\u2010Aldrich Syndrome Protein (WASP) and WASP interacting protein (WIP) in neuroblastoma cell line, SH\u2010SY\u20105y. The RP\u2010L10 was associated with the SH3 domains of Src and Yes. It is shown that two different regions of RP\u2010L10 are associated with the Src\u2010SH3. The effect of ectopic RP\u2010L10 expression on neuronal cell scaffolding was explored in cells transiently transfected with QM. SH\u2010SY\u20105y human neuroblastoma cells transfected with QM were considerably more susceptible to neurite outgrowth induced by glial cell line\u2010derived neurotrophic factor (GDNF). However, RP\u2010L10 did not directly interact with actin assembly. Taken together, these results suggest that the RP\u2010L10 may positively regulate the GDNF\/Ret\u2010mediated signaling of neurite outgrowth in the neuroblastoma cell line, SH\u2010SY\u20105y. J. Cell. Biochem. 99: 624\u2013634, 2006. \u00a9 2006 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/jcb.20888","type":"journal-article","created":{"date-parts":[[2006,6,1]],"date-time":"2006-06-01T21:19:35Z","timestamp":1149196775000},"page":"624-634","source":"Crossref","is-referenced-by-count":16,"title":["Ribosomal protein L10 interacts with the SH3 domain and regulates GDNF\u2010induced neurite growth in SH\u2010SY\u20105y 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