{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T11:19:53Z","timestamp":1772795993381,"version":"3.50.1"},"reference-count":36,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2004,2,19]],"date-time":"2004-02-19T00:00:00Z","timestamp":1077148800000},"content-version":"vor","delay-in-days":3428,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Cellular Biochemistry"],"published-print":{"date-parts":[[1994,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Computer simulation of calcium homeostasis in chicks predicted an oscillatory behavior of bone calcium flow and kidney 25\u2010hydroxyvitamin D<jats:sub>3<\/jats:sub>\u20101 hydroxylase with a periodicity of 56 h and a 9 h phase difference between the two signals. In growing chickens subjected to a light: dark cycle of 22:2 h, and intravenously dosed with <jats:sup>45<\/jats:sup>Ca, the temporal changes in plasma <jats:sup>45<\/jats:sup>Ca could be described by an exponential decline with superimposed diurnal oscillations. The activity of the renal 25\u2010hydpoxyvitamil D<jats:sub>3<\/jats:sub>\u20101\u2010hydroxylase in chicks subjected to a 12:12 h light: dark cycle ALSO followed diupnal oscillations, with a ladir at the beginning of the light period and a peak 12 h later. The production of 1,25\u2010dihydroxyvitamin D<jats:sub>3<\/jats:sub> by primary cultures of chicken kidney cells mscillated with a periodicity of 5.6 h or shorter. It is suggested that despite the differences in phase and periodicity between the simulation predictions and actual results, the oscillations in both 1\u2010hydroxylase and bone calcium flow could be coupled through the hormonal systems involved in regulation of plasma calcium.<\/jats:p>","DOI":"10.1002\/jcb.240560218","type":"journal-article","created":{"date-parts":[[2005,5,28]],"date-time":"2005-05-28T21:47:01Z","timestamp":1117316821000},"page":"236-244","source":"Crossref","is-referenced-by-count":2,"title":["Oscillatory behavior of control\u2010systems of calcium homeostasis in chickens"],"prefix":"10.1002","volume":"56","author":[{"given":"S.","family":"Hurwitz","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Barbara","family":"Miller","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. 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