{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T01:35:47Z","timestamp":1790127347067,"version":"4.0.1"},"reference-count":48,"publisher":"Wiley","issue":"S22","license":[{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":7548,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Cell. Biochem."],"published-print":{"date-parts":[[1995]]},"DOI":"10.1002\/jcb.240590805","type":"journal-article","created":{"date-parts":[[2005,5,28]],"date-time":"2005-05-28T22:16:04Z","timestamp":1117318564000},"page":"24-32","source":"Crossref","is-referenced-by-count":100,"title":["N-Acetylcysteine (NAC) and glutathione (GSH): Antioxidant and chemopreventive properties, with special reference to lung cancer"],"prefix":"10.1002","volume":"59","author":[{"given":"Nico","family":"van Zandwijk","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"key":"10.1002\/jcb.240590805-BIB1","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1056\/NEJM199009203231205","volume":"323","author":"Hong","year":"1990","journal-title":"New Engle J Med"},{"key":"10.1002\/jcb.240590805-BIB2","first-page":"1","volume-title":"Lung Cancer. Textbook for General Practitioners","author":"Hansen","year":"1990","unstructured":"(ed): \u201cLung Cancer. Textbook for General Practitioners.\u201d Berlin, Germany: Springer Verlag, 1990, pp 1-58."},{"key":"10.1002\/jcb.240590805-BIB3","doi-asserted-by":"crossref","first-page":"1191","DOI":"10.1093\/jnci\/66.6.1192","volume":"66","author":"Doll","year":"1981","journal-title":"J Natl Cancer Inst"},{"key":"10.1002\/jcb.240590805-BIB4","doi-asserted-by":"crossref","first-page":"1272","DOI":"10.1093\/jnci\/82.15.1272","volume":"82","author":"Sellers","year":"1990","journal-title":"J Natl Cancer Inst"},{"key":"10.1002\/jcb.240590805-BIB5","first-page":"289","volume":"30","author":"Tokuhata","year":"1963","journal-title":"J Natl Cancer Inst"},{"key":"10.1002\/jcb.240590805-BIB6","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1002\/ijc.2910390505","volume":"39","author":"Karki","year":"1987","journal-title":"Int J Cancer"},{"key":"10.1002\/jcb.240590805-BIB7","first-page":"83","volume-title":"Nutrition and Cancer Prevention: Investigating the Role of Micronutrients","author":"Hunter","year":"1989","unstructured":": Human epidemiological evidence on the nutritional prevention of cancer. In (eds): \u201cNutrition and Cancer Prevention: Investigating the Role of Micronutrients.\u201d New York: Marcel Dekker Inc, 1989, pp 83-100."},{"key":"10.1002\/jcb.240590805-BIB8","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/0027-5107(88)90193-5","volume":"202","author":"De Flora","year":"1988","journal-title":"Mutat Res"},{"key":"10.1002\/jcb.240590805-BIB9","doi-asserted-by":"crossref","first-page":"122s","DOI":"10.1016\/0002-9343(91)90295-9","volume":"3C","author":"De Flora","year":"1991","journal-title":"Am J Med"},{"key":"10.1002\/jcb.240590805-BIB10","first-page":"76","volume":"66","author":"Cantin","year":"1985","journal-title":"Eur J Respir Dis"},{"key":"10.1002\/jcb.240590805-BIB11","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1289\/ehp.8564111","volume":"64","author":"Church","year":"1985","journal-title":"Environ Health Perspect"},{"key":"10.1002\/jcb.240590805-BIB12","first-page":"149","volume":"97","author":"Hunninghake","year":"1979","journal-title":"Am J Pathol"},{"key":"10.1002\/jcb.240590805-BIB13","first-page":"85","volume":"123","author":"Hoidal","year":"1981","journal-title":"Am Rev Respir Dis"},{"key":"10.1002\/jcb.240590805-BIB14","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/0002-9343(91)90280-B","volume":"91","author":"Cochrane","year":"1991","journal-title":"Am J Med"},{"key":"10.1002\/jcb.240590805-BIB15","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1016\/S0022-5223(19)32956-3","volume":"44","author":"Webb","year":"1962","journal-title":"J Thorac Cardiovasc Surg"},{"key":"10.1002\/jcb.240590805-BIB16","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/S0022-3476(63)80067-0","volume":"62","author":"Reas","year":"1963","journal-title":"J Pediatr"},{"key":"10.1002\/jcb.240590805-BIB17","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1016\/S0306-039X(78)90010-7","volume":"3","author":"Richardson","year":"1978","journal-title":"Pharmacol Ther [B]"},{"key":"10.1002\/jcb.240590805-BIB18","first-page":"346","volume":"74","author":"Hirsch","year":"1969","journal-title":"Lab Clin Med"},{"key":"10.1002\/jcb.240590805-BIB19","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1146\/annurev.bi.52.070183.003431","volume":"52","author":"Meister","year":"1983","journal-title":"Ann Rev Biochem"},{"key":"10.1002\/jcb.240590805-BIB20","first-page":"45","volume":"61","author":"Bonanomi","year":"1980","journal-title":"Eur J Resp Dis"},{"key":"10.1002\/jcb.240590805-BIB21","doi-asserted-by":"crossref","first-page":"621","DOI":"10.3109\/00498257809069574","volume":"8","author":"Turnbull","year":"1978","journal-title":"Xenobiotica"},{"key":"10.1002\/jcb.240590805-BIB22","first-page":"81","volume":"61","author":"Aylward","year":"1980","journal-title":"Eur J Resp Dis"},{"key":"10.1002\/jcb.240590805-BIB23","first-page":"93","volume":"61","author":"Multicenter study group","year":"1980","journal-title":"Eur J Resp Dis"},{"key":"10.1002\/jcb.240590805-BIB24","first-page":"405","volume":"64","author":"Boman","year":"1983","journal-title":"Eur J Resp Dis"},{"key":"10.1002\/jcb.240590805-BIB25","author":"Grassi","year":"1992","unstructured":": The role of oxidantsantioxidants in chronic bronchitis. International Medical Forum Preventive and Therapeutic Strategies for Lung Protection. October 30-31, Sorrento, Italy, 1992 (abstract)."},{"key":"10.1002\/jcb.240590805-BIB26","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1016\/0891-5849(90)90015-B","volume":"9","author":"Doelman","year":"1990","journal-title":"Free Rad Biol Med"},{"key":"10.1002\/jcb.240590805-BIB27","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1002\/cpt1974164676","volume":"16","author":"Mitchell","year":"1974","journal-title":"Clin Pharmacol Ther"},{"key":"10.1002\/jcb.240590805-BIB28","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1007\/BF03260008","volume":"2","author":"Flanagan","year":"1987","journal-title":"Med Toxicol"},{"key":"10.1002\/jcb.240590805-BIB29","first-page":"76","volume":"10","author":"Miller","year":"1983","journal-title":"Semin Oncol"},{"key":"10.1002\/jcb.240590805-BIB30","first-page":"266","volume":"29","author":"Morgan","year":"1981","journal-title":"Clin Pharmacol Ther"},{"key":"10.1002\/jcb.240590805-BIB31","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/0305-7372(90)90048-K","volume":"17","author":"Tedeschi","year":"1990","journal-title":"Cancer Treat Rev"},{"key":"10.1002\/jcb.240590805-BIB32","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1093\/carcin\/5.4.505","volume":"5","author":"De Flora","year":"1984","journal-title":"Carcinogenesis"},{"key":"10.1002\/jcb.240590805-BIB33","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1159\/000195086","volume":"50","author":"Mold\u00e9us","year":"1986","journal-title":"Respiration"},{"key":"10.1002\/jcb.240590805-BIB34","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/0014-5793(84)80938-2","volume":"176","author":"Berggren","year":"1984","journal-title":"FEBS Lett"},{"key":"10.1002\/jcb.240590805-BIB35","doi-asserted-by":"crossref","first-page":"1735","DOI":"10.1093\/carcin\/6.12.1735","volume":"6","author":"De Flora","year":"1985","journal-title":"Carcinogenesis"},{"key":"10.1002\/jcb.240590805-BIB36","first-page":"275","volume-title":"Anticarcinogenesis and Radiation Protection. Strategies in Protection from Radiation and Cancer","author":"De Flora","year":"1991","unstructured":": Antimutagenic and anticarcinogenic mechanisms of aminothiols. In (ed): \u201cAnticarcinogenesis and Radiation Protection. Strategies in Protection from Radiation and Cancer.\u201d New York: Plenum Press, 1991, pp 275-285."},{"key":"10.1002\/jcb.240590805-BIB37","first-page":"183","volume-title":"Cancer Chemoprevention","author":"De Flora","year":"1992","unstructured":": Chemopreventive properties of N-acetylcysteine and other thiols. In (eds): \u201cCancer Chemoprevention.\u201d Boca Raton: CRC Press, 1992, pp 183-194."},{"key":"10.1002\/jcb.240590805-BIB38","first-page":"3581","volume":"48","author":"Cesarone","year":"1988","journal-title":"Cancer Res"},{"key":"10.1002\/jcb.240590805-BIB39","first-page":"261","volume-title":"Anticarcinogenesis and Radiation Protection. Strategies in Protection from Radiation and Cancer","author":"Cesarone","year":"1991","unstructured":": Protection of nuclear enzymes by aminothiols. In (ed): \u201cAnticarcinogenesis and Radiation Protection. Strategies in Protection from Radiation and Cancer.\u201d New York: Plenum Press, 1991, pp 261-268."},{"key":"10.1002\/jcb.240590805-BIB40","first-page":"15","volume-title":"Chemoimmunoprevention of Cancer","author":"Izzotti","year":"1991","unstructured":": Chemoprevention of carcinogen-DNA adduct formation. In (eds): \u201cChemoimmunoprevention of Cancer.\u201d New York: Thieme-Verlag, 1991, pp 15-19."},{"key":"10.1002\/jcb.240590805-BIB41","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/0304-3835(86)90175-8","volume":"32","author":"De Flora","year":"1986","journal-title":"Cancer Lett"},{"key":"10.1002\/jcb.240590805-BIB42","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1016\/0027-5107(88)90203-5","volume":"202","author":"Rotstein","year":"1988","journal-title":"Mutat Res"},{"key":"10.1002\/jcb.240590805-BIB43","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/0304-3835(86)90154-0","volume":"131","author":"Wilpart","year":"1986","journal-title":"Caccer Lett"},{"key":"10.1002\/jcb.240590805-BIB44","first-page":"85","volume":"1","author":"Cesarone","year":"1987","unstructured":": Effects of aminothiols in 2-acetylaminofluorene treated rats. I. Damage and repair of liver DNA, hyperplastic foci, and Zymbal gland tumors. In vivo 1:85-91, 1987.","journal-title":"In vivo"},{"key":"10.1002\/jcb.240590805-BIB45","doi-asserted-by":"crossref","first-page":"1621","DOI":"10.1093\/carcin\/7.10.1621","volume":"7","author":"Chan","year":"1986","journal-title":"Carcinogenesis"},{"key":"10.1002\/jcb.240590805-BIB46","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/0027-5107(92)90069-E","volume":"267","author":"Bone","year":"1992","journal-title":"Mutat Res"},{"key":"10.1002\/jcb.240590805-BIB47","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/0304-3835(92)90072-4","volume":"64","author":"Balansky","year":"1992","journal-title":"Cancer Lett"},{"key":"10.1002\/jcb.240590805-BIB48","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/0169-5002(93)90690-Y","volume":"9","author":"van Zandwijk","year":"1993","journal-title":"Lung Cancer"}],"container-title":["Journal of Cellular Biochemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjcb.240590805","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full\/10.1002\/jcb.240590805","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,5]],"date-time":"2021-07-05T20:18:17Z","timestamp":1625516297000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jcb.240590805"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1995]]},"references-count":48,"journal-issue":{"issue":"S22","published-print":{"date-parts":[[1995]]}},"URL":"https:\/\/doi.org\/10.1002\/jcb.240590805","relation":{},"ISSN":["0730-2312","1097-4644"],"issn-type":[{"value":"0730-2312","type":"print"},{"value":"1097-4644","type":"electronic"}],"subject":[],"published":{"date-parts":[[1995]]}}}