{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T09:53:54Z","timestamp":1760954034964},"reference-count":48,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2015,11,19]],"date-time":"2015-11-19T00:00:00Z","timestamp":1447891200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100000024","name":"Canadian Institutes of Health Research","doi-asserted-by":"publisher","award":["MOP\u201068992"],"award-info":[{"award-number":["MOP\u201068992"]}],"id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Cellular Biochemistry"],"published-print":{"date-parts":[[2016,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:label \/><jats:p><jats:italic>Chlamydia trachomatis<\/jats:italic>, the leading cause of bacterial sexually transmitted infections, disrupts cytokinesis and causes significant multinucleation in host cells. Here, we demonstrate that multinuclear cells that result from unsuccessful cell division contain significantly higher Golgi content, an important source of lipids for chlamydiae. Using immunofluorescence and fluorescent live cell imaging, we show that <jats:italic>C. trachomatis<\/jats:italic> in multinuclear cells indeed intercept Golgi\u2010derived lipid faster than in mononuclear cells. Moreover, multinuclear cells enhance <jats:italic>C. trachomatis<\/jats:italic> inclusion growth and infectious particle formation. Together, these results indicate that <jats:italic>C. trachomatis<\/jats:italic> robustly position inclusions to the cell equator to disrupt host cell division in order to acquire host Golgi\u2010derived lipids more quickly in multinucleated progeny cells. J. Cell. Biochem. 117: 132\u2013143, 2016. \u00a9 2015 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jcb.25258","type":"journal-article","created":{"date-parts":[[2015,6,18]],"date-time":"2015-06-18T00:04:17Z","timestamp":1434585857000},"page":"132-143","source":"Crossref","is-referenced-by-count":10,"title":["<i>Chlamydia trachomatis<\/i> Inclusion Disrupts Host Cell Cytokinesis to Enhance Its Growth in Multinuclear Cells"],"prefix":"10.1002","volume":"117","author":[{"given":"He Song","family":"Sun","sequence":"first","affiliation":[{"name":"Department of Biological Sciences University of Toronto 1265 Military Trail Toronto Ontario M1C 1A4 Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alex T.\u2010W.","family":"Sin","sequence":"additional","affiliation":[{"name":"Department of Biological Sciences University of Toronto 1265 Military Trail Toronto Ontario M1C 1A4 Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mathieu 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