{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T13:49:57Z","timestamp":1783432197528,"version":"3.54.6"},"reference-count":49,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2017,4,18]],"date-time":"2017-04-18T00:00:00Z","timestamp":1492473600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1"},{"start":{"date-parts":[[2017,4,18]],"date-time":"2017-04-18T00:00:00Z","timestamp":1492473600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81501672"],"award-info":[{"award-number":["81501672"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004608","name":"Natural Science Foundation of Jiangsu Province","doi-asserted-by":"publisher","award":["BK20140083"],"award-info":[{"award-number":["BK20140083"]}],"id":[{"id":"10.13039\/501100004608","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008562","name":"Nanjing Agricultural University","doi-asserted-by":"publisher","award":["YKK15159"],"award-info":[{"award-number":["YKK15159"]}],"id":[{"id":"10.13039\/501100008562","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008045","name":"Nanjing University of Information Science and Technology","doi-asserted-by":"publisher","award":["201503047"],"award-info":[{"award-number":["201503047"]}],"id":[{"id":"10.13039\/501100008045","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Cell. Biochem."],"published-print":{"date-parts":[[2017,8]]},"DOI":"10.1002\/jcb.25873","type":"journal-article","created":{"date-parts":[[2017,1,9]],"date-time":"2017-01-09T10:33:23Z","timestamp":1483958003000},"page":"1965-1968","source":"Crossref","is-referenced-by-count":43,"title":["Non-Coding RNAs: The New Insight on Hypertrophic Scar"],"prefix":"10.1002","volume":"118","author":[{"given":"Ling","family":"Chen","sequence":"first","affiliation":[{"name":"Department of Plastic and Cosmetic Surgery; Maternal and Child Health Medical Institute; Obstetrics and Gynecology Hospital Affiliated to Nanjing Medical University; Nanjing 210004 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingyun","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Plastic and Cosmetic Surgery; Maternal and Child Health Medical Institute; Obstetrics and Gynecology Hospital Affiliated to Nanjing Medical University; Nanjing 210004 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qian","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Plastic and Cosmetic Surgery; Maternal and Child Health Medical Institute; Obstetrics and Gynecology Hospital Affiliated to Nanjing Medical University; Nanjing 210004 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui","family":"Yan","sequence":"additional","affiliation":[{"name":"Department of Plastic and Cosmetic Surgery; Maternal and Child Health Medical Institute; Obstetrics and Gynecology Hospital Affiliated to Nanjing Medical University; Nanjing 210004 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bei","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Plastic and Cosmetic Surgery; Maternal and Child Health Medical Institute; Obstetrics and Gynecology Hospital Affiliated to Nanjing Medical University; Nanjing 210004 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanli","family":"Gao","sequence":"additional","affiliation":[{"name":"Department of Plastic and Cosmetic Surgery; Maternal and Child Health Medical Institute; Obstetrics and Gynecology Hospital Affiliated to Nanjing Medical University; Nanjing 210004 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Plastic and Cosmetic Surgery; Maternal and Child Health Medical Institute; Obstetrics and Gynecology Hospital Affiliated to Nanjing Medical University; Nanjing 210004 China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,4,18]]},"reference":[{"key":"10.1002\/jcb.25873-BIB0001|jcb25873-cit-0001","doi-asserted-by":"crossref","first-page":"1","DOI":"10.4103\/1947-2714.92892","article-title":"Collagen IV in normal skin and in pathological processes","volume":"4","author":"Abreu-Velez","year":"2012","journal-title":"N Am J Med Sci"},{"key":"10.1002\/jcb.25873-BIB0002|jcb25873-cit-0002","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1007\/s00403-013-1410-1","article-title":"The role of microRNAs in skin fibrosis","volume":"305","author":"Babalola","year":"2013","journal-title":"Arch Dermatol Res"},{"key":"10.1002\/jcb.25873-BIB0003|jcb25873-cit-0003","doi-asserted-by":"crossref","first-page":"1298","DOI":"10.1016\/j.cell.2013.02.012","article-title":"Long noncoding RNAs: Cellular address codes in development and disease","volume":"152","author":"Batista","year":"2013","journal-title":"Cell"},{"key":"10.1002\/jcb.25873-BIB0004|jcb25873-cit-0004","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1111\/j.1540-9740.2005.02507.x","article-title":"Clinical management of skin scarring","volume":"4","author":"Bayat","year":"2005","journal-title":"Skinmed"},{"key":"10.1002\/jcb.25873-BIB0005|jcb25873-cit-0005","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1002\/hep.24071","article-title":"What goes up must come down: The emerging role of microRNA in fibrosis","volume":"53","author":"Chau","year":"2011","journal-title":"Hepatology"},{"key":"10.1002\/jcb.25873-BIB0006|jcb25873-cit-0006","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1046\/j.1523-1747.1999.00477.x","article-title":"Stimulation of type I collagen transcription in human skin fibroblasts by TGF-beta: Involvement of Smad 3","volume":"112","author":"Chen","year":"1999","journal-title":"J Invest Dermatol"},{"key":"10.1002\/jcb.25873-BIB0007|jcb25873-cit-0007","doi-asserted-by":"crossref","first-page":"6973","DOI":"10.1073\/pnas.102657399","article-title":"Beta-Catenin stabilization dysregulates mesenchymal cell proliferation, motility, and invasiveness and causes aggressive fibromatosis and hyperplastic cutaneous wounds","volume":"99","author":"Cheon","year":"2002","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1002\/jcb.25873-BIB0008|jcb25873-cit-0008","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/j.yexcr.2003.09.029","article-title":"Growth factors regulate beta-catenin-mediated TCF-dependent transcriptional activation in fibroblasts during the proliferative phase of wound healing","volume":"293","author":"Cheon","year":"2004","journal-title":"Exp Cell Res"},{"key":"10.1002\/jcb.25873-BIB0009|jcb25873-cit-0009","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1038\/sj.jid.5700701","article-title":"Inflammation in wound repair: Molecular and cellular mechanisms","volume":"127","author":"Eming","year":"2007","journal-title":"J Invest Dermatol"},{"key":"10.1002\/jcb.25873-BIB0010|jcb25873-cit-0010","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.jdermsci.2016.03.003","article-title":"Bone marrow derived mesenchymal stem cells inhibit the proliferative and profibrotic phenotype of hypertrophic scar fibroblasts and keloid fibroblasts through paracrine signaling","volume":"83","author":"Fang","year":"2016","journal-title":"J Dermatol Sci"},{"key":"10.1002\/jcb.25873-BIB0011|jcb25873-cit-0011","doi-asserted-by":"crossref","first-page":"e59056","DOI":"10.1371\/journal.pone.0059056","article-title":"Genome-wide analysis using exon arrays demonstrates an important role for expression of extra-cellular matrix, fibrotic control and tissue remodelling genes in Dupuytren's disease","volume":"8","author":"Forrester","year":"2013","journal-title":"PLoS ONE"},{"key":"10.1002\/jcb.25873-BIB0012|jcb25873-cit-0012","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1007\/s12032-013-0588-6","article-title":"Overexpression of long noncoding RNA PCAT-1 is a novel biomarker of poor prognosis in patients with colorectal cancer","volume":"30","author":"Ge","year":"2013","journal-title":"Med Oncol"},{"key":"10.1002\/jcb.25873-BIB0013|jcb25873-cit-0013","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1111\/j.1365-2362.1995.tb01742.x","article-title":"Reverse transcription-polymerase chain reaction detection of collagen transcripts in healing human wounds","volume":"25","author":"Hopkinson","year":"1995","journal-title":"Eur J Clin Invest"},{"key":"10.1002\/jcb.25873-BIB0014|jcb25873-cit-0014","doi-asserted-by":"crossref","first-page":"4337","DOI":"10.1016\/S0021-9258(17)35666-1","article-title":"Transforming growth factor-beta stimulates the expression of fibronectin and collagen and their incorporation into the extracellular matrix","volume":"261","author":"Ignotz","year":"1986","journal-title":"J Biol Chem"},{"key":"10.1002\/jcb.25873-BIB0015|jcb25873-cit-0015","doi-asserted-by":"crossref","first-page":"e10316","DOI":"10.1371\/journal.pone.0010316","article-title":"Mining mammalian transcript data for functional long non-coding RNAs","volume":"5","author":"Khachane","year":"2010","journal-title":"PLoS ONE"},{"key":"10.1002\/jcb.25873-BIB0016|jcb25873-cit-0016","first-page":"1","article-title":"Circular RNAs: The emerging class of non-coding RNAs and their potential role in human neurodegenerative diseases","volume":"119","author":"Kumar","year":"2016","journal-title":"Mol Neurobiol"},{"key":"10.1002\/jcb.25873-BIB0017|jcb25873-cit-0017","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1093\/carcin\/bgu232","article-title":"Epigenetic modulation and repression of miR-200b by cancer-associated fibroblasts contribute to cancer invasion and peritoneal dissemination in gastric cancer","volume":"36","author":"Kurashige","year":"2015","journal-title":"Carcinogenesis"},{"key":"10.1002\/jcb.25873-BIB0018|jcb25873-cit-0018","doi-asserted-by":"crossref","first-page":"e0123054","DOI":"10.1371\/journal.pone.0123054","article-title":"MicroRNA 181b regulates decorin production by dermal fibroblasts and may be a potential therapy for hypertrophic scar","volume":"10","author":"Kwan","year":"2015","journal-title":"PLoS ONE"},{"key":"10.1002\/jcb.25873-BIB0019|jcb25873-cit-0019","doi-asserted-by":"crossref","first-page":"692","DOI":"10.1093\/abbs\/gmt057","article-title":"Comparative study of microRNA profiling in keloid fibroblast and annotation of differential expressed microRNAs","volume":"45","author":"Li","year":"2013","journal-title":"Acta Biochim Biophys Sin (Shanghai)"},{"key":"10.1002\/jcb.25873-BIB0020|jcb25873-cit-0020","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1111\/1346-8138.12600","article-title":"Overexpression of miR-200b inhibits the cell proliferation and promotes apoptosis of human hypertrophic scar fibroblasts in vitro","volume":"41","author":"Li","year":"2014","journal-title":"J Dermatol"},{"key":"10.1002\/jcb.25873-BIB0021|jcb25873-cit-0021","doi-asserted-by":"crossref","first-page":"1676","DOI":"10.1038\/jid.2015.48","article-title":"MicroRNA-31 promotes skin wound healing by enhancing keratinocyte proliferation and migration","volume":"135","author":"Li","year":"2015a","journal-title":"J Invest Dermatol"},{"key":"10.1002\/jcb.25873-BIB0022|jcb25873-cit-0022","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1159\/000369727","article-title":"Distinct expression profiles of lncRNAs between regressive and mature scars","volume":"35","author":"Li","year":"2015b","journal-title":"Cell Physiol Biochem"},{"key":"10.1002\/jcb.25873-BIB0023|jcb25873-cit-0023","doi-asserted-by":"crossref","first-page":"17559","DOI":"10.18632\/oncotarget.2755","article-title":"By downregulating TIAM1 expression, microRNA-329 suppresses gastric cancer invasion and growth","volume":"6","author":"Li","year":"2015c","journal-title":"Oncotarget"},{"key":"10.1002\/jcb.25873-BIB0024|jcb25873-cit-0024","doi-asserted-by":"crossref","first-page":"4229","DOI":"10.3892\/mmr.2016.5062","article-title":"MicroRNA-29b inhibits TGF-beta1-induced fibrosis via regulation of the TGF-beta1\/Smad pathway in primary human endometrial stromal cells","volume":"13","author":"Li","year":"2016a","journal-title":"Mol Med Rep"},{"key":"10.1002\/jcb.25873-BIB0025|jcb25873-cit-0025","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1159\/000452548","article-title":"The long non-coding RNA lncRNA8975-1 is upregulated in hypertrophic scar fibroblasts and controls collagen expression","volume":"40","author":"Li","year":"2016b","journal-title":"Cell Physiol Biochem"},{"key":"10.1002\/jcb.25873-BIB0026|jcb25873-cit-0026","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1016\/j.burns.2011.10.014","article-title":"MicroRNA profiling in denatured dermis of deep burn patients","volume":"38","author":"Liang","year":"2012","journal-title":"Burns"},{"key":"10.1002\/jcb.25873-BIB0027|jcb25873-cit-0027","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1007\/s00266-011-9773-1","article-title":"MiRNA expression profiles in keloid tissue and corresponding normal skin tissue","volume":"36","author":"Liu","year":"2012","journal-title":"Aesthetic Plast Surg"},{"key":"10.1002\/jcb.25873-BIB0028|jcb25873-cit-0028","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1586\/1744666X.2015.1020301","article-title":"MiRNAs in inflammatory skin diseases and their clinical implications","volume":"11","author":"Lovendorf","year":"2015","journal-title":"Expert Rev Clin Immunol"},{"key":"10.1002\/jcb.25873-BIB0029|jcb25873-cit-0029","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1007\/s11010-016-2699-9","article-title":"MicroRNA-143-3p inhibits hyperplastic scar formation by targeting connective tissue growth factor CTGF\/CCN2 via the Akt\/mTOR pathway","volume":"416","author":"Mu","year":"2016","journal-title":"Mol Cell Biochem"},{"key":"10.1002\/jcb.25873-BIB0030|jcb25873-cit-0030","first-page":"692","article-title":"Differential expression profile of microRNA between hyperplastic scar and normal skin","volume":"92","author":"Ning","year":"2012","journal-title":"Zhonghua Yi Xue Za Zhi"},{"key":"10.1002\/jcb.25873-BIB0031|jcb25873-cit-0031","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1002\/path.2081","article-title":"Epithelial-mesenchymal interactions in keloid pathogenesis modulate vascular endothelial growth factor expression and secretion","volume":"211","author":"Ong","year":"2007","journal-title":"J Pathol"},{"key":"10.1002\/jcb.25873-BIB0032|jcb25873-cit-0032","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1111\/1523-1747.ep12480289","article-title":"Activation of collagen gene expression in keloids: Co-localization of type I and VI collagen and transforming growth factor-beta 1 mRNA","volume":"97","author":"Peltonen","year":"1991","journal-title":"J Invest Dermatol"},{"key":"10.1002\/jcb.25873-BIB0033|jcb25873-cit-0033","doi-asserted-by":"crossref","first-page":"19945","DOI":"10.1074\/jbc.M102382200","article-title":"Functional characterization of transforming growth factor beta signaling in Smad2- and Smad3-deficient fibroblasts","volume":"276","author":"Piek","year":"2001","journal-title":"J Biol Chem"},{"key":"10.1002\/jcb.25873-BIB0034|jcb25873-cit-0034","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jaad.2011.05.055","article-title":"Cutaneous scarring: Pathophysiology, molecular mechanisms, and scar reduction therapeutics Part I. The molecular basis of scar formation","volume":"66","author":"Profyris","year":"2012","journal-title":"J Am Acad Dermatol"},{"key":"10.1002\/jcb.25873-BIB0035|jcb25873-cit-0035","doi-asserted-by":"crossref","first-page":"1077","DOI":"10.7314\/APJCP.2013.14.2.1077","article-title":"Long non-coding RNA GAS5 functions as a tumor suppressor in renal cell carcinoma","volume":"14","author":"Qiao","year":"2013","journal-title":"Asian Pac J Cancer Prev"},{"key":"10.1002\/jcb.25873-BIB0036|jcb25873-cit-0036","doi-asserted-by":"crossref","first-page":"565","DOI":"10.6061\/clinics\/2014(08)11","article-title":"Update on hypertrophic scar treatment","volume":"69","author":"Rabello","year":"2014","journal-title":"Clinics (Sao Paulo)"},{"key":"10.1002\/jcb.25873-BIB0037|jcb25873-cit-0037","doi-asserted-by":"crossref","first-page":"836","DOI":"10.1016\/j.jaci.2014.05.022","article-title":"MicroRNA-146a alleviates chronic skin inflammation in atopic dermatitis through suppression of innate immune responses in keratinocytes","volume":"134","author":"Rebane","year":"2014","journal-title":"J Allergy Clin Immunol"},{"key":"10.1002\/jcb.25873-BIB0038|jcb25873-cit-0038","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1097\/00006534-198911000-00021","article-title":"Keloids and hypertrophic scars: A comprehensive review","volume":"84","author":"Rockwell","year":"1989","journal-title":"Plast Reconstr Surg"},{"key":"10.1002\/jcb.25873-BIB0039|jcb25873-cit-0039","doi-asserted-by":"crossref","first-page":"23001","DOI":"10.1074\/jbc.M109.002808","article-title":"Secreted versus membrane-anchored collagenases: Relative roles in fibroblast-dependent collagenolysis and invasion","volume":"284","author":"Sabeh","year":"2009","journal-title":"J Biol Chem"},{"issue":"Pt 3","key":"10.1002\/jcb.25873-BIB0040|jcb25873-cit-0040","doi-asserted-by":"crossref","first-page":"985","DOI":"10.1242\/jcs.108.3.985","article-title":"Neutralisation of TGF-beta 1 and TGF-beta 2 or exogenous addition of TGF-beta 3 to cutaneous rat wounds reduces scarring","volume":"108","author":"Shah","year":"1995","journal-title":"J Cell Sci"},{"key":"10.1002\/jcb.25873-BIB0041|jcb25873-cit-0041","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/j.canlet.2013.06.013","article-title":"Long non-coding RNAs: A new frontier in the study of human diseases","volume":"339","author":"Shi","year":"2013","journal-title":"Cancer Lett"},{"key":"10.1002\/jcb.25873-BIB0042|jcb25873-cit-0042","doi-asserted-by":"crossref","first-page":"2070","DOI":"10.1038\/sj.mt.6300311","article-title":"MicroRNAs in disease and potential therapeutic applications","volume":"15","author":"Soifer","year":"2007","journal-title":"Mol Ther"},{"key":"10.1002\/jcb.25873-BIB0043|jcb25873-cit-0043","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1111\/1523-1747.ep12343428","article-title":"Human dermal fibroblasts produce nitric oxide and express both constitutive and inducible nitric oxide synthase isoforms","volume":"106","author":"Wang","year":"1996","journal-title":"J Invest Dermatol"},{"key":"10.1002\/jcb.25873-BIB0044|jcb25873-cit-0044","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1111\/cpr.12146","article-title":"MiR-99a directly targets the mTOR signalling pathway in breast cancer side population cells","volume":"47","author":"Yang","year":"2014","journal-title":"Cell Prolif"},{"key":"10.1002\/jcb.25873-BIB0045|jcb25873-cit-0045","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1097\/00000637-199605000-00011","article-title":"Role of growth factors in scar contraction: An in vitro analysis","volume":"36","author":"Younai","year":"1996","journal-title":"Ann Plast Surg"},{"key":"10.1002\/jcb.25873-BIB0046|jcb25873-cit-0046","doi-asserted-by":"crossref","first-page":"923","DOI":"10.3892\/ijmm.2014.1853","article-title":"MicroRNAs regulate vascular smooth muscle cell functions in atherosclerosis (review)","volume":"34","author":"Yu","year":"2014","journal-title":"Int J Mol Med"},{"key":"10.1002\/jcb.25873-BIB0047|jcb25873-cit-0047","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1007\/s10735-012-9453-8","article-title":"Elevated expression of pleiotrophin in human hypertrophic scars","volume":"44","author":"Zhang","year":"2013","journal-title":"J Mol Histol"},{"key":"10.1002\/jcb.25873-BIB0048|jcb25873-cit-0048","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1016\/j.yexcr.2015.10.018","article-title":"Aberrant miR-21 and miR-200b expression and its pro-fibrotic potential in hypertrophic scars","volume":"339","author":"Zhou","year":"2015","journal-title":"Exp Cell Res"},{"key":"10.1002\/jcb.25873-BIB0049|jcb25873-cit-0049","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1007\/s12079-013-0195-5","article-title":"The molecular mechanism of hypertrophic scar","volume":"7","author":"Zhu","year":"2013","journal-title":"J Cell Commun Signal"}],"container-title":["Journal of Cellular Biochemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjcb.25873","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full\/10.1002\/jcb.25873","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,7,21]],"date-time":"2022-07-21T00:41:57Z","timestamp":1658364117000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jcb.25873"}},"subtitle":["NON-C<scp>ODING<\/scp>RNAs<scp>IN<\/scp>H<scp>YPERTROPHIC<\/scp>S<scp>CAR<\/scp>"],"short-title":[],"issued":{"date-parts":[[2017,4,18]]},"references-count":49,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2017,8]]}},"URL":"https:\/\/doi.org\/10.1002\/jcb.25873","archive":["Portico"],"relation":{},"ISSN":["0730-2312"],"issn-type":[{"value":"0730-2312","type":"print"}],"subject":[],"published":{"date-parts":[[2017,4,18]]}}}