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Although surgical repair has been shown to be somewhat effective, many patients may still suffer from reduced shoulder function. The aim of the current study was to identify a more effective mode of RCI treatment by investigating the effect of platelet\u2010derived growth factor subunit B (PDGF\u2010B) on tendon\u2010bone healing after RCI repair by modifying bone marrow\u2013derived mesenchymal stem cells (BMSCs). Surface markers of BMSCs were initially detected by means of flow cytometry, followed by establishment of the rat models and construction of the lentiviral vector. 3\u2010(4,5\u2010dimethyl\u20102\u2010thiazolyl)\u20102,5\u2010diphenyl\u20102\u2010H\u2010tetrazolium bromide, Thiazolyl Blue Tetrazolium Bromide (MTT) assay, alizarin red staining, and oil red O staining were used to provide verification that PDGF\u2010B was indeed capable of promoting BMSC viability, osteogenic and adipogenic differentiation capability. Furthermore, biomechanical assessment results indicated that PDGF\u2010B could increase the ultimate load and stiffness of the tendon tissue. Real\u2010time reverse\u2010transcription quantitative polymerase chain reaction and Western blot analysis methods provided evidence suggesting that PDGF\u2010B facilitated the expression of tendon\u2010bone healing\u2013related genes and proteins, while contrasting results were obtained after PDGF\u2010B silencing. Taken together, the key findings of the current study provided evidence suggesting that overexpressed PDGF\u2010B could act to enhance tendon\u2010bone healing after RCI repair, thus highlighting the potential of the functional promotion of PDGF\u2010B as a future RCI therapeutic approach.<\/jats:p>","DOI":"10.1002\/jcb.27143","type":"journal-article","created":{"date-parts":[[2018,8,14]],"date-time":"2018-08-14T06:04:14Z","timestamp":1534226654000},"page":"8897-8908","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["<i>Retracted<\/i>: Platelet\u2010derived growth factor subunit B is required for tendon\u2010bone healing using bone marrow\u2013derived mesenchymal stem cells after rotator cuff repair in 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