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The retina is composed of light\u2010sensitive cells that absorb light and convert it into neural signals. These signals are sent to the brain for visual recognition. It has been shown that many pathogenesis conditions, including in\ufb02ammation, angiogenesis, oxidative stress, and imbalanced histone modi\ufb01cations in the retina are associated with initiation and progression of retinal diseases (ie, glaucoma, diabetic retinopathy, and age\u2010related macular degeneration). Currently available treatments include laser surgery, freezing, stem\u2010cell therapy, shrinking abnormal blood vessels. It has some limitations, such as invasive methods, high costs, and many side effects. Hence, finding a new therapeutic platform for stopping or slowing of the disease progression is required. Curcumin is a natural product, which is associated with a wide range of properties, such as antioxidant, anti\u2010inflammatory, antiangiogenic, and antitumor activates. It exerts therapeutic effects via activation\/inhibition cellular and molecular targets\u00a0involved in various diseases, such as retinal diseases. Increasing evidence revealed that curcumin can be used as a therapeutic option in the treatment of different retinal diseases. Here, we summarized various clinical and preclinical studies that used curcumin as a therapeutic agent in the treatment of retinal disorders.<\/jats:p>","DOI":"10.1002\/jcb.28068","type":"journal-article","created":{"date-parts":[[2018,12,12]],"date-time":"2018-12-12T01:43:52Z","timestamp":1544579032000},"page":"6886-6893","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Curcumin: A new candidate for retinal disease therapy?"],"prefix":"10.1002","volume":"120","author":[{"given":"Hasan","family":"Farajipour","sequence":"first","affiliation":[{"name":"Kashan University of Medical Sciences Kashan Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan","family":"Rahimian","sequence":"additional","affiliation":[{"name":"Oral and Maxillofacial Radiology Department, School of Dentistry, Kashan University of Medical Sciences Kashan 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