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In this study, we proved that LINC00961 expression was downregulated in TSCC cells (Tca8113, SCC1, SCC\u20104, and SCC\u201015) compared with normal tissue. In addition, we showed that LINC00961 expression was downregulated in TSCC samples compared with matched normal tissues. Moreover, ectopic expression of LINC00961 decreased TSCC cell growth and invasion and suppressed epithelial\u2010mesenchymal transition in TSCC cell. Furthermore, we indicated that overexpression of LINC00961 decreased \u03b2\u2010catenin expression. Knockdown of LINC00961 promoted cell proliferation and invasion partly via promoting the Wnt\/\u03b2\u2010catenin signaling pathway. These results suggested that LINC00961 was downregulated in TSCC tissues and acted as a tumor suppressor gene in the development of TSCC.<\/jats:p>","DOI":"10.1002\/jcb.28509","type":"journal-article","created":{"date-parts":[[2019,3,11]],"date-time":"2019-03-11T06:09:58Z","timestamp":1552284598000},"page":"12429-12435","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Long noncoding RNA LINC00961 inhibited cell proliferation and invasion through regulating the Wnt\/\u03b2\u2010catenin signaling pathway in tongue squamous cell carcinoma"],"prefix":"10.1002","volume":"120","author":[{"given":"Lixia","family":"Zhang","sequence":"first","affiliation":[{"name":"Jinan Stomatological Hospital Jinan China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Linqin","family":"Shao","sequence":"additional","affiliation":[{"name":"Jinan Stomatological Hospital Jinan 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