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Identifying prognostic factors for KT could help guide the management of this tumor. We used a meta\u2010analysis to evaluate the prognostic value of metastasectomy and other factors in patients with KT to develop a treatment plan. We searched literature in PubMed, Cochrane library and EMBASE. We analyzed hazard ratios (HR) and 95% confidence intervals (CI) with respect to overall survival (OS). The meta\u2010analysis included 12 cohort studies with 1,031 patients associated with longer OS following metastasectomy (HR\u2009=\u20090.41; 95% CI\u2009=\u20090.32\u20130.53; <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001), R0 resection (HR\u2009=\u20090.37; 95% CI\u2009=\u20090.26\u20130.53; <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001), metachronous ovarian metastasis (HR\u2009=\u20090.74; 95% CI\u2009=\u20090.58\u20130.93; <jats:italic>P<\/jats:italic>\u2009=\u20090.012), size of KT (&lt;5\u2009cm) (HR\u2009=\u20090.74; 95% CI\u2009=\u20090.58\u20130.95; <jats:italic>P<\/jats:italic>\u2009=\u20090.019), ECOG PS (Eastern Cooperative Oncology Group performance status) 0 to 1 (HR\u2009=\u20090.48; 95% CI\u2009=\u20090.29\u20130.80; <jats:italic>P<\/jats:italic>\u2009\u2009=\u20090.004), tumor confined to ovary (HR\u2009=\u20090.40; 95% CI\u2009=\u20090.16\u20130.99; <jats:italic>P<\/jats:italic>\u2009\u2009=\u20090.047), and tumor confined to pelvic cavity (HR\u2009=\u20090.36; 95% CI\u2009=\u20090.14\u20130.92; <jats:italic>P<\/jats:italic>\u2009\u2009=\u20090.033). Shorter OS was associated with peritoneal carcinomatosis (HR\u2009=\u20092.00; 95% CI\u2009=\u20091.25\u20133.21; <jats:italic>P<\/jats:italic>\u2009\u2009=\u20090.004), ascites (HR\u2009=\u20091.66; 95% CI\u2009=\u20091.19\u20132.31; <jats:italic>P<\/jats:italic>\u2009\u2009=\u20090.003) and positive CEA (HR\u2009=\u20091.41; 95% CI\u2009=\u20091.10\u20131.82; <jats:italic>P<\/jats:italic>\u2009\u2009=\u20090.007). Gastrectomy led to a slight improvement in OS, but without statistical significance (HR\u2009=\u20090.69; 95% CI\u2009=\u20090.47\u20131.02; <jats:italic>P<\/jats:italic>\u2009\u2009=\u20090.061). No significant difference in OS was observed in patients with signet\u2010ring cells (HR\u2009=\u20091.17; 95% CI\u2009=\u20090.91\u20131.51; <jats:italic>P<\/jats:italic>\u2009\u2009=\u20090.226), bilateral ovarian metastasis (HR\u2009=\u20090.87; 95% CI\u2009=\u20090.70\u20131.08; <jats:italic>P<\/jats:italic>\u2009\u2009=\u20090.212), age\u2009\u2265\u200950 years (HR\u2009=\u20090.93; 95% CI\u2009=\u20090.71\u20131.22; <jats:italic>P<\/jats:italic>\u2009\u2009=\u20090.619), positive CA19\u20109 (HR\u2009=\u20091.01; 95% CI\u2009=\u20090.75\u20131.35; <jats:italic>P<\/jats:italic>\u2009\u2009=\u20090.960), and positive CA\u2010125 (HR\u2009=\u20090.98; 95% CI\u2009=\u20090.73\u20131.33; <jats:italic>P\u2009<\/jats:italic>\u2009=\u20090.915). Various factors affect OS in patients with KT.<\/jats:p>","DOI":"10.1002\/jcb.28708","type":"journal-article","created":{"date-parts":[[2019,5,3]],"date-time":"2019-05-03T13:00:35Z","timestamp":1556888435000},"page":"14486-14498","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Effects of metastasectomy and other factors on survival of patients with ovarian metastases from gastric cancer: a systematic review and meta\u2010analysis"],"prefix":"10.1002","volume":"120","author":[{"given":"Chao","family":"Zhang","sequence":"first","affiliation":[{"name":"Department of Surgical Oncology First Affiliated Hospital of China Medical University  155 Nanjing North Street, Heping District Shenyang China"},{"name":"Key Laboratory of Gastric Cancer Molecular Pathology of Liaoning Province, 155 Nanjing North Street, Heping District Shenyang 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