{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,11,17]],"date-time":"2023-11-17T17:10:09Z","timestamp":1700241009772},"reference-count":9,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2003,4,9]],"date-time":"2003-04-09T00:00:00Z","timestamp":1049846400000},"content-version":"vor","delay-in-days":98,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Laboratory Analysis"],"published-print":{"date-parts":[[2003,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>In this study, we investigated whether glucose\u20106\u2010phosphate dehydrogenase (G6PD) promoter mutations are responsible for G6PD deficiency. We analysed the G6PD proximal promoter and the 5\u2032 untranslated region (UTR) in 65 G6PD\u2010deficient individuals, in which no mutations have been found in the G6PD gene coding sequences, using a nonradioactive polymerase chain reaction\/single\u2010strand conformation polymorphism (PCR\/SSCP) analysis. We identified no sequence variations in the G6PD core promoter or in the 5\u2032 UTR of these G6PD\u2010deficient individuals, which indicates that G6PD deficiency is not associated with promoter mutations in the G6PD locus. J. Clin. Lab. Anal. 17:90\u201392, 2003. \u00a9 2003 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/jcla.10075","type":"journal-article","created":{"date-parts":[[2003,4,10]],"date-time":"2003-04-10T10:01:48Z","timestamp":1049968908000},"page":"90-92","source":"Crossref","is-referenced-by-count":5,"title":["Glucose\u20106\u2010phosphate dehydrogenase deficiency does not result from mutations in the promoter region of the G6PD gene"],"prefix":"10.1002","volume":"17","author":[{"given":"Panayiotis G.","family":"Menounos","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"George A.","family":"Garinis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"George P.","family":"Patrinos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2003,4,9]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1006\/rwgn.2001.1520"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/humu.10036"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V92.7.2527"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1159\/000022922"},{"key":"e_1_2_1_6_2","first-page":"81","volume-title":"Red cell metabolism: a manual of biochemical methods","author":"Beutler E","year":"1984"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/0378-1119(91)90078-P"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0014-5793(98)01259-9"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00439-002-0783-6"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1002\/j.1460-2075.1988.tb02827.x"}],"container-title":["Journal of Clinical Laboratory Analysis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjcla.10075","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jcla.10075","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,17]],"date-time":"2023-11-17T16:54:29Z","timestamp":1700240069000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jcla.10075"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,1]]},"references-count":9,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2003,1]]}},"alternative-id":["10.1002\/jcla.10075"],"URL":"https:\/\/doi.org\/10.1002\/jcla.10075","archive":["Portico"],"relation":{},"ISSN":["0887-8013","1098-2825"],"issn-type":[{"value":"0887-8013","type":"print"},{"value":"1098-2825","type":"electronic"}],"subject":[],"published":{"date-parts":[[2003,1]]}}}