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Glutaraldehyde pretreatment of the samples results in the development of complexes with highly favourable electrophoretic mobility and precipitating capacity. By this chemical modification and use of a double set of samples with varying antigen\u2010antibody, proportion, the sensitivity of haemoglobin detection in erythrocyte\u2010containing haemolysate and native blood was 300 ng\/ml. The examination is easily performed, and without considerable outlay, even with conventional laboratory facilities. It is equally suitable for the detection of occult colorectal bleeding and for species\u2010specific study of blood stains of unknown origin.<\/jats:p><jats:p>The authors succeeded in identifying human haemoglobin even in a 42\u2010month dried blood stain.<\/jats:p>","DOI":"10.1002\/jcla.1860050602","type":"journal-article","created":{"date-parts":[[2007,3,5]],"date-time":"2007-03-05T20:01:32Z","timestamp":1173124892000},"page":"373-377","source":"Crossref","is-referenced-by-count":4,"title":["Sensitized immunochemical method for the specific detection of human haemoglobin in dried biological samples"],"prefix":"10.1002","volume":"5","author":[{"given":"Szabolcs","family":"Ott\u00f3","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M\u00e1ria Sz.","family":"N\u00e9meth","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gy\u00f6rgy","family":"Kocsis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Istv\u00e1n","family":"Tulok","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katalin","family":"Kelemen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,10,20]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(81)90118-5"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1093\/ajcp\/69.1.342"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1445-2197.1982.tb06128.x"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF01497404"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.1984.26"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19800315)45:5 <1099::AID-CNCR2820451312>3.0.CO;2-T"},{"key":"e_1_2_1_8_2","doi-asserted-by":"crossref","first-page":"1763","DOI":"10.1093\/clinchem\/34.9.1758","article-title":"Rapid immunochemical detection of fecal occult blood by use of a latex\u2010agglutination test","volume":"34","author":"V\u00e1\u00e1n\u00e1nen P","year":"1988","journal-title":"Clin Chem"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1445-5994.1984.tb04268.x"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19851001)56:7<1549::AID-CNCR2820560714>3.0.CO;2-#"},{"key":"e_1_2_1_11_2","first-page":"343","article-title":"Immunochemical confirmation of gastrointestinal bleeding","volume":"4","author":"Adams EC","year":"1974","journal-title":"Ann Clin Lab Sci"},{"key":"e_1_2_1_12_2","first-page":"187","article-title":"Immunological method for the determination of occult intestinal bleeding and its place in two\u2010step screening system","volume":"31","author":"Ott\u00f3 SZ","year":"1987","journal-title":"Magy Onkol"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.296.6629.1092"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF01892897"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.1985.269"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/0009-8981(85)90189-5"},{"key":"e_1_2_1_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/0006-3002(59)90261-6"},{"key":"e_1_2_1_18_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF02092265"},{"key":"e_1_2_1_19_2","doi-asserted-by":"crossref","first-page":"1982","DOI":"10.1093\/clinchem\/22.12.1982","article-title":"Immunofixation. 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