{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T06:58:24Z","timestamp":1774594704735,"version":"3.50.1"},"reference-count":28,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2005,10,20]],"date-time":"2005-10-20T00:00:00Z","timestamp":1129766400000},"content-version":"vor","delay-in-days":5041,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Laboratory Analysis"],"published-print":{"date-parts":[[1992,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We determined platelet\u2010associated IgG (PAIgG) levels in patients with aplastic anemia, idiopathic thrombocytopenic purpura (ITP), iron deficiency anemia, and systemic lupus erythematosus (SLE), as well as in normal healthy adults as a control group. To determine PAIgG levels, we used a competitive micro enzyme\u2010linked immunosorbent assay, which had excellent reproducibility, recovery, and dilution. We confirmed its reliability by comparing it to the immunoradiometric assay. Both the aplastic anemia group (n = 27, mean \u00b1 SD = 218.6 \u00b1 244.6ng\/10<jats:sup>7<\/jats:sup> platelets) and the ITP group (n = 82, mean \u00b1 SD = 212.5 \u00b1 327.8 ng\/10<jats:sup>7<\/jats:sup> platelets) had higher PAIgG levels than the SLE group (n = 4, mean \u00b1 SD = 38.4 \u00b1 22.4 ng\/10<jats:sup>7<\/jats:sup> platelets), iron deficiency anemia group (n = 10, mean \u00b1 SD = 16.1 \u00b1 3.6ng\/10<jats:sup>7<\/jats:sup> platelets), and normal control group (n) = 69, mean \u00b1 SD = 16.1 \u00b1 3.6ng\/10<jats:sup>7<\/jats:sup> platelets. The higher platelet associated IgG levels in aplastic anemia suggest that autoimmune mechanisms are involved. \u00a9 1992 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/jcla.1860060306","type":"journal-article","created":{"date-parts":[[2007,3,5]],"date-time":"2007-03-05T20:23:15Z","timestamp":1173126195000},"page":"130-135","source":"Crossref","is-referenced-by-count":4,"title":["Elevation of platelet\u2010associated IgG in aplastic anemia"],"prefix":"10.1002","volume":"6","author":[{"given":"Ryuji","family":"Kawaguchi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shoji","family":"Haruna","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazumasa","family":"Hikiji","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasuko","family":"Higashi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yutaka","family":"Tsukada","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,10,20]]},"reference":[{"key":"e_1_2_1_2_2","first-page":"1","article-title":"Determination of a thrombocytopenic factor in the blood of patients with thrombocytopenic purpura","volume":"38","author":"Harrington WJ","year":"1951","journal-title":"J 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