{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,25]],"date-time":"2023-10-25T15:40:56Z","timestamp":1698248456579},"reference-count":11,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2005,10,20]],"date-time":"2005-10-20T00:00:00Z","timestamp":1129766400000},"content-version":"vor","delay-in-days":4675,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Laboratory Analysis"],"published-print":{"date-parts":[[1993,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Filarial IgM antibody response to various antigenic fractions isolated from immune complexes by SDS\u2010PAGE viz., IC\u20102, IC\u20104, IC\u20107, and IC\u20109, was studied by ELISA. The IgM antibody response to almost all antigenic fractions was seen more in microfilaraemic group compared to the clinical filariasis group. The antibody response to IC\u20109 antigen fraction as compared to other fractions was found significantly higher in microfilaraemic patients than in patients with clinical manifestations. Ninety percent of microfilariae carriers and 75% of clinical filarial patients have shown IgM isotype to IC\u20109 antigen. Studies with various lectins have revealed the Con A binding nature of IC\u20109 antigen. This study suggests that IC\u20109 antigen could be another candidate antigen in the immunodiagnosis of lymphatic filariasis. \u00a9 1993 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/jcla.1860070204","type":"journal-article","created":{"date-parts":[[2007,3,5]],"date-time":"2007-03-05T20:51:20Z","timestamp":1173127880000},"page":"91-94","source":"Crossref","is-referenced-by-count":1,"title":["Analysis of human sera for filarial IgM antibody using antigen fractions isolated from immune complexes"],"prefix":"10.1002","volume":"7","author":[{"given":"G. B. K. 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