{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T18:21:36Z","timestamp":1773858096235,"version":"3.50.1"},"reference-count":30,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2011,11,15]],"date-time":"2011-11-15T00:00:00Z","timestamp":1321315200000},"content-version":"vor","delay-in-days":14,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Laboratory Analysis"],"published-print":{"date-parts":[[2011,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:italic>Background<\/jats:italic>: Though recent reports have indicated a higher prevalence of latent tuberculosis infection (LTBI) in laboratory personnel than in other healthcare workers, these studies included only a limited number of laboratory personnel. <jats:italic>Methods<\/jats:italic>: We have thus focused on the laboratory personnel, who had a high level of exposure to specimens from patients with TB. We recruited 173 laboratory personnel and performed QuantiFERON\u2010TB Gold In\u2010Tube test (QFT\u2010G) and tuberculin skin test (TST). <jats:italic>Results<\/jats:italic>: QFT\u2010G was positive in 21.4% of the enrolled laboratory personnel, and TST was positive in 33.3%. The agreement between the two tests was fair (\u03ba = 0.234). In multivariate analyses, household contactwith TBpatients (<jats:italic>P<\/jats:italic> = 0.013), the laboratory sections of microbiology (<jats:italic>P<\/jats:italic> = 0.045) and chemistry\/immunology (<jats:italic>P<\/jats:italic> = 0.014) were shown to be significantly associated with positive QFT\u2010G results. <jats:italic>Conclusion<\/jats:italic>: Our data show a high prevalence of TST and QFT\u2010G positivity in laboratory personnel and emphasize the importance of LTBI screening for laboratory personnel. In BCG\u2010vaccinated populations with an intermediate incidence setting, QFT\u2010G seems to be superior to TST as a screening tool for the detection of LTBI. Further study, including results of follow\u2010up tests will be helpful for confirmation of our findings. J. Clin. Lab. Anal. 25:382\u2013388, 2011. \u00a9 2011 Wiley Periodicals, Inc.<\/jats:p>","DOI":"10.1002\/jcla.20479","type":"journal-article","created":{"date-parts":[[2011,11,16]],"date-time":"2011-11-16T13:47:15Z","timestamp":1321451235000},"page":"382-388","source":"Crossref","is-referenced-by-count":11,"title":["Latent tuberculosis infection screening for laboratory personnel using interferon\u2010\u03b3 release assay and tuberculin skin test in Korea: an intermediate incidence 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