{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,11,22]],"date-time":"2023-11-22T00:08:22Z","timestamp":1700611702307},"reference-count":29,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2012,9,21]],"date-time":"2012-09-21T00:00:00Z","timestamp":1348185600000},"content-version":"vor","delay-in-days":20,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Laboratory Analysis"],"published-print":{"date-parts":[[2012,9]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>The aim was to examine the relationship of fat distributions with adipokines concentrations in <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content>\u2010infected patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This was a cross\u2010sectional analysis of 36 <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content> (free of lipodystrophy) infected patients. Dual\u2010energy <jats:styled-content style=\"fixed-case\">X<\/jats:styled-content>\u2010ray absorptiometry was used.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In the multivariate analysis, basal adiponectin concentration was a dependent variable, whereas waist to hip ratio and abdominal fat mass were independent predictors in the model (<jats:italic>F<\/jats:italic> = 5.1; <jats:italic>P<\/jats:italic> &lt; 0.05). Adiponectin concentration decreases by 5.541.2 \u03bcg\/ml (<jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 95%: 8,071.9\u20133,029.1) for each unit of waist to hip ratio and 561.9 ng\/ml (<jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 95%: 918.2\u2013213.4) for each kilogram of fat mass of abdominal area. In the multivariate analysis, basal leptin concentration was a dependent variable, whereas waist circumference remained an independent predictor in the model (<jats:italic>F<\/jats:italic> = 6.3; <jats:italic>P<\/jats:italic> &lt; 0.05), with a direct correlation. Leptin concentration increases by 0.067 ng\/ml (<jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 95%: 0.001\u20130.12) for each centimeter of waist circumference.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Leptin and adiponectin are related with adiposity in <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content>\u2010infected patients. J. Clin. Lab. Anal. 26:336\u2010341, 2012. \u00a9 2012 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jcla.21528","type":"journal-article","created":{"date-parts":[[2012,9,21]],"date-time":"2012-09-21T16:05:00Z","timestamp":1348243500000},"page":"336-341","source":"Crossref","is-referenced-by-count":5,"title":["Relationship of Fat Distribution With Adipokines in Patients With Acquired Immunodeficiency Virus Infection"],"prefix":"10.1002","volume":"26","author":[{"given":"Daniel A.","family":"de Luis","sequence":"first","affiliation":[{"name":"Facultad de Medicina Centro de Investigacion en Endocrinologia y Nutricion Clinica (I.E.N) Unit of Investigation Hospital Universitario Rio Hortega  Valladolid 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