{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:04:03Z","timestamp":1790813043337,"version":"4.1.0"},"reference-count":36,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2013,1,24]],"date-time":"2013-01-24T00:00:00Z","timestamp":1358985600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Laboratory Analysis"],"published-print":{"date-parts":[[2013,3]]},"abstract":"<jats:p>We collected and analyzed the time to detection (<jats:styled-content style=\"fixed-case\">TTD<\/jats:styled-content>) of blood cultures in the <jats:styled-content style=\"fixed-case\">B<\/jats:styled-content>ac<jats:styled-content style=\"fixed-case\">T<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>lert automated system from 2002 to 2007. Among the 10,893 monomicrobial isolates from a total of 133,735 blood culture sets, the recoveries of aerobic bottles were compared with those of anaerobic bottles in this study. Significantly more <jats:styled-content style=\"fixed-case\">G<\/jats:styled-content>ram\u2010positive cocci (except <jats:italic><jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>taphylococcus aureus<\/jats:italic> and enterococci), glucose nonfermentative <jats:styled-content style=\"fixed-case\">G<\/jats:styled-content>ram\u2010negative bacteria, and yeast were recovered from aerobic bottles than from anaerobic bottles. The average <jats:styled-content style=\"fixed-case\">TTD<\/jats:styled-content> was 19.0 hr and 20.1 hr for the aerobic and anaerobic bottles, respectively, and 96.8% of the microorganisms were detected within the first 72 hr. Of the 5,489 microorganisms recovered from both of the blood culture bottle pair, microbial growth was significantly more often detected first in the anaerobic bottles than the aerobic bottles for <jats:italic><jats:styled-content style=\"fixed-case\">E<\/jats:styled-content>nterobacteriaceae<\/jats:italic> except <jats:italic><jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>erratia marcescens<\/jats:italic>, while <jats:italic><jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>. aureus<\/jats:italic>, coagulase\u2010negative staphylococci and <jats:italic><jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>seudomonas aeruginosa<\/jats:italic> were more often detected first in the aerobic bottles. According to these data, we conclude that the earlier positivity of anaerobic bottles is a useful marker for rapid presumptive identification of <jats:italic><jats:styled-content style=\"fixed-case\">E<\/jats:styled-content>nterobacteriaceae<\/jats:italic> infection. J. Clin. Lab. Anal. 27:113\u2013120, 2013. \u00a9 2013 Wiley Periodicals, Inc.<\/jats:p>","DOI":"10.1002\/jcla.21571","type":"journal-article","created":{"date-parts":[[2013,1,24]],"date-time":"2013-01-24T17:38:29Z","timestamp":1359049109000},"page":"113-120","source":"Crossref","is-referenced-by-count":2,"title":["Predominance of <i><scp>E<\/scp>nterobacteriaceae<\/i> Isolates in Early Positive Anaerobic Blood Culture Bottles in <scp>B<\/scp>ac<scp>T<\/scp>\/Alert System"],"prefix":"10.1002","volume":"27","author":[{"given":"Tzong\u2010Shi","family":"Chiueh","sequence":"first","affiliation":[{"name":"Graduate Institute of Medical Science National Defense Medical Center and Tri\u2010Service General Hospital Taipei Taiwan"},{"name":"Division of Clinical Pathology Department of Pathology National Defense Medical Center and Tri\u2010Service General Hospital Taipei 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