{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T08:04:58Z","timestamp":1777449898702,"version":"3.51.4"},"reference-count":53,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2016,4,13]],"date-time":"2016-04-13T00:00:00Z","timestamp":1460505600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100004085","name":"Ministry of Education, Science and Technology","doi-asserted-by":"publisher","award":["2014028083"],"award-info":[{"award-number":["2014028083"]}],"id":[{"id":"10.13039\/501100004085","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004085","name":"Ministry of Education, Science and Technology","doi-asserted-by":"publisher","award":["2014064216"],"award-info":[{"award-number":["2014064216"]}],"id":[{"id":"10.13039\/501100004085","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Laboratory Analysis"],"published-print":{"date-parts":[[2016,11]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>High C\u2010reactive protein (CRP) and mean platelet volume (MPV) levels are associated with poor prognosis in patients with ST\u2010segment elevation myocardial infarction (STEMI). The aim of this study was to evaluate the relationship between CRP level or MPV and infarct transmurality in patients with STEMI.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We retrospectively reviewed CRP level, MPV, and infarct transmurality in 112 STEMI patients who were assessed with contrast\u2010enhanced cardiac magnetic resonance imaging.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>When the cut\u2010off peak CRP level and MPV were set at 2.35 mg\/dl and 7.3 fl using receiver operating characteristic curves analysis, the sensitivity was 67.3\/69.2% and specificity was 76.7\/76.7% for differentiating between the groups with and those without transmural involvement. Peak CRP level, MPV, peak creatine kinase\u2010MB (CK\u2010MB) level, and peak high\u2010sensitivity cardiac troponin T (hs\u2010cTnT) level had comparable predictive values for transmural involvement (area under the curve, 0.749, 0.761, 0.680, and 0.696, respectively). High peak CRP level and MPV were independent predictors of transmural involvement after adjusting for the peak CK\u2010MB level, peak hs\u2010cTnT level, baseline thrombolysis in myocardial infarction flow grade, and left ventricular ejection fraction (odds ratio: 5.16\/5.42, 95% confidence interval: 1.84\u201314.50\/2.03\u201314.47, <jats:italic>P<\/jats:italic> = 0.002\/0.001, respectively) in the logistic regression analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The results of this study show that peak CRP level and MPV are predictive markers for transmural involvement. Their predictive power for transmural involvement is independent of and comparable to that of peak CK\u2010MB and hs\u2010cTnT levels.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jcla.21959","type":"journal-article","created":{"date-parts":[[2016,4,14]],"date-time":"2016-04-14T02:23:16Z","timestamp":1460600596000},"page":"930-940","source":"Crossref","is-referenced-by-count":6,"title":["Prediction of Infarct Transmurality From C\u2010Reactive Protein Level and Mean Platelet Volume in Patients With ST\u2010Elevation Myocardial Infarction: Comparison of the Predictive Values of Cardiac Enzymes"],"prefix":"10.1002","volume":"30","author":[{"given":"DongHun","family":"Kim","sequence":"first","affiliation":[{"name":"Department of Radiology Chosun University School of Medicine  Gwangju Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dong\u2010Hyun","family":"Choi","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Chosun University School of Medicine  Gwangju Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bo\u2010Bae","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Chosun University School of Medicine  Gwangju Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seo\u2010Won","family":"Choi","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Chosun University School of Medicine  Gwangju Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keun Ho","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Chosun University School of Medicine  Gwangju Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Heesang","family":"Song","sequence":"additional","affiliation":[{"name":"Department of Biochemistry and Molecular Biology Chosun University School of Medicine  Gwangju Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,4,13]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.3109\/09537104.2011.560306"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.3109\/09537104.2013.821606"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.3109\/09537104.2012.710858"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.2174\/13816128113199990075"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.3109\/09537104.2013.835393"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2014.06.028"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1538-7836.2009.03584.x"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2012.09.014"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2005.03.065"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0008-6363(01)00434-5"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.eurheartj.a015068"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2009.06.014"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.RES.0000130526.20854.fa"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.95.2.320"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2796.2008.02015.x"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-5890(01)00042-6"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI200318921"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2006.07.039"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinbiochem.2006.10.025"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2005.10.055"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1536\/ihj.47.833"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-8703(03)00098-X"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1186\/1532-429X-14-68"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcmg.2012.01.016"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.2003.023101"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncpcardio1373"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1161\/hc3501.096798"},{"key":"e_1_2_6_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2008.01.019"},{"key":"e_1_2_6_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcmg.2009.02.011"},{"key":"e_1_2_6_31_1","doi-asserted-by":"publisher","DOI":"10.3904\/kjim.2005.20.1.21"},{"key":"e_1_2_6_32_1","doi-asserted-by":"publisher","DOI":"10.3904\/kjim.2014.29.4.454"},{"key":"e_1_2_6_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cardiores.2005.01.011"},{"key":"e_1_2_6_34_1","doi-asserted-by":"publisher","DOI":"10.1093\/cvr\/cvp032"},{"key":"e_1_2_6_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejim.2006.07.031"},{"key":"e_1_2_6_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinbiochem.2012.05.026"},{"key":"e_1_2_6_37_1","doi-asserted-by":"publisher","DOI":"10.1124\/jpet.102.040600"},{"key":"e_1_2_6_38_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.190.12.1733"},{"key":"e_1_2_6_39_1","doi-asserted-by":"publisher","DOI":"10.1002\/jca.21344"},{"key":"e_1_2_6_40_1","doi-asserted-by":"publisher","DOI":"10.1159\/000320763"},{"key":"e_1_2_6_41_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra071014"},{"key":"e_1_2_6_42_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.061607398"},{"key":"e_1_2_6_43_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm1102-1227"},{"key":"e_1_2_6_44_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.96.1.69"},{"key":"e_1_2_6_45_1","doi-asserted-by":"publisher","DOI":"10.1161\/ATVBAHA.110.221788"},{"key":"e_1_2_6_46_1","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.2006.094763"},{"key":"e_1_2_6_47_1","doi-asserted-by":"publisher","DOI":"10.1080\/09537100802458969"},{"key":"e_1_2_6_48_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11239-009-0353-z"},{"key":"e_1_2_6_49_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2006.05.022"},{"key":"e_1_2_6_50_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000027818.15792.1E"},{"key":"e_1_2_6_51_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehi131"},{"key":"e_1_2_6_52_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehi147"},{"key":"e_1_2_6_53_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200011163432003"},{"key":"e_1_2_6_54_1","doi-asserted-by":"publisher","DOI":"10.1097\/MBC.0b013e32835d9bca"}],"container-title":["Journal of Clinical Laboratory Analysis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjcla.21959","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jcla.21959","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,3]],"date-time":"2023-10-03T21:19:34Z","timestamp":1696367974000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jcla.21959"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,4,13]]},"references-count":53,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2016,11]]}},"alternative-id":["10.1002\/jcla.21959"],"URL":"https:\/\/doi.org\/10.1002\/jcla.21959","archive":["Portico"],"relation":{},"ISSN":["0887-8013","1098-2825"],"issn-type":[{"value":"0887-8013","type":"print"},{"value":"1098-2825","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,4,13]]}}}