{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T20:03:57Z","timestamp":1788552237091,"version":"build-2803163510"},"reference-count":6,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2016,6,27]],"date-time":"2016-06-27T00:00:00Z","timestamp":1466985600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Laboratory Analysis"],"published-print":{"date-parts":[[2017,1]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>For analysis of urine samples during abstinence control for driving ability assessment (medical and psychological assessment, <jats:styled-content style=\"fixed-case\">MPA<\/jats:styled-content>), a reliable screening method for ethyl glucuronide and drugs of abuse (cannabinoids, opiates, cocaine, amphetamines, methadone, and benzodiazepines) is needed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In this study <jats:styled-content style=\"fixed-case\">CEDIA<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">DRI<\/jats:styled-content> immunoassays were applied on a Thermo Fisher Scientific Indiko Plus analyzer. Precision and accuracy as well as sensitivity and specificity at the required cut\u2010offs for the <jats:styled-content style=\"fixed-case\">MPA<\/jats:styled-content> were evaluated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The specificity was satisfactory and ranged from 91% for methamphetamine to 100% for opiates, cocaine metabolite, amphetamine, <jats:styled-content style=\"fixed-case\">EDDP<\/jats:styled-content>, and benzodiazepines. Moreover, sensitivity was 100% for all assays except for cannabinoids (91%).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The presented method can therefore be recommended for abstinence control.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jcla.22021","type":"journal-article","created":{"date-parts":[[2016,6,27]],"date-time":"2016-06-27T11:30:25Z","timestamp":1467027025000},"source":"Crossref","is-referenced-by-count":12,"title":["Evaluation of CEDIA and DRI Drugs of Abuse Immunoassays for Urine Screening on a Thermo Indiko Plus Analyzer"],"prefix":"10.1002","volume":"31","author":[{"given":"Katharina M.","family":"K\u00f6hler","sequence":"first","affiliation":[{"name":"Institute for Forensic Medicine Medical Center \u2013 University of Freiburg Faculty of Medicine, University of Freiburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raija","family":"Hammer","sequence":"additional","affiliation":[{"name":"Institute for Forensic Medicine Medical Center \u2013 University of Freiburg Faculty of Medicine, University of Freiburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathrin","family":"Riedy","sequence":"additional","affiliation":[{"name":"Institute for Forensic Medicine Medical Center \u2013 University of Freiburg Faculty of Medicine, University of Freiburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Volker","family":"Auw\u00e4rter","sequence":"additional","affiliation":[{"name":"Institute for Forensic Medicine Medical Center \u2013 University of Freiburg Faculty of Medicine, University of Freiburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Merja A.","family":"Neukamm","sequence":"additional","affiliation":[{"name":"Institute for Forensic Medicine Medical Center \u2013 University of Freiburg Faculty of Medicine, University of Freiburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,6,27]]},"reference":[{"key":"e_1_2_6_2_1","volume-title":"Beurteilungskriterien: Urteilsbildung in der Fahreignungsbegutachtung","author":"Schubert W","year":"2013"},{"key":"e_1_2_6_3_1","first-page":"185","article-title":"Anhang B zu den Richtlinien der GTFCh zur Qualit\u00e4tssicherung bei forensisch\u2010toxikologischen Untersuchungen; Anforderungen an die Validierung von Analysenmethoden","volume":"76","author":"Peters FT","year":"2009","journal-title":"Toxichem Krimtech"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/dta.1454"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.forsciint.2010.09.002"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.forsciint.2011.10.034"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/clinchem\/39.4.561"}],"container-title":["Journal of Clinical Laboratory Analysis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjcla.22021","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjcla.22021","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jcla.22021","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,3]],"date-time":"2023-10-03T12:10:54Z","timestamp":1696335054000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jcla.22021"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,6,27]]},"references-count":6,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017,1]]}},"alternative-id":["10.1002\/jcla.22021"],"URL":"https:\/\/doi.org\/10.1002\/jcla.22021","archive":["Portico"],"relation":{},"ISSN":["0887-8013","1098-2825"],"issn-type":[{"value":"0887-8013","type":"print"},{"value":"1098-2825","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,6,27]]},"article-number":"e22021"}}