{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,5]],"date-time":"2026-11-05T14:55:17Z","timestamp":1793890517735,"version":"4.8.0"},"reference-count":19,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2017,2,15]],"date-time":"2017-02-15T00:00:00Z","timestamp":1487116800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Laboratory Analysis"],"published-print":{"date-parts":[[2018,1]]},"abstract":"Background<\/jats:title>Information on serum albumin and trace elements among children suffering from Sickle Cell Anemia (SCA<\/jats:styled-content>) was poorly documented in Africa. The aim of this study was to describe and to compare different values of trace elements with published reports from other parts of the world.<\/jats:p><\/jats:sec>Methods<\/jats:title>We carried out a case\u2013control study. Seventy\u2010six steady state children suffering from SCA<\/jats:styled-content> (Hb\u2010SS<\/jats:styled-content>). One hundred and fifty\u2010two children were recruited with 76 (cases, Hb\u2010SS<\/jats:styled-content>) and 76 (control, Hb\u2010AA<\/jats:styled-content>) to compare the data.<\/jats:p><\/jats:sec>Results<\/jats:title>The mean age was 10.0\u00a0years (SD<\/jats:styled-content>=5.4) in SCA<\/jats:styled-content> children and 9.2\u00a0years (SD<\/jats:styled-content>=4.7) in the control group. The mean level of zinc and magnesium were slightly lower in the Hb\u2010SS<\/jats:styled-content> group than in the Hb\u2010AA<\/jats:styled-content> group (P<\/jats:italic><.001).<\/jats:p><\/jats:sec>Conclusion<\/jats:title>The first literature about trace elements in SCA<\/jats:styled-content> is briefly reported in Central Africa. In our midst, zinc, magnesium, and selenium deficiencies underline the need for their systematic among all children with SCA<\/jats:styled-content> to identify patients with these deficiencies and provide early management.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jcla.22160","type":"journal-article","created":{"date-parts":[[2017,2,16]],"date-time":"2017-02-16T04:47:25Z","timestamp":1487220445000},"source":"Crossref","is-referenced-by-count":10,"title":["Trace elements in children suffering from sickle cell anemia: A case\u2013control study"],"prefix":"10.1002","volume":"32","author":[{"given":"Joseph K.","family":"Sungu","sequence":"first","affiliation":[{"name":"Department of Pediatrics University Hospital of Lubumbashi University of Lubumbashi Kinshasa the Democratic Republic of Congo"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olivier","family":"Mukuku","sequence":"additional","affiliation":[{"name":"Department of Pediatrics University Hospital of Lubumbashi University of Lubumbashi Kinshasa the Democratic Republic of Congo"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Augustin Mulangu","family":"Mutombo","sequence":"additional","affiliation":[{"name":"Department of Pediatrics University Hospital of Lubumbashi University of Lubumbashi Kinshasa the Democratic Republic of Congo"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Mawaw","sequence":"additional","affiliation":[{"name":"School of Public Health University of Lubumbashi Lubumbashi the Democratic Republic of Congo"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7479-1170","authenticated-orcid":false,"given":"Michel N.","family":"Aloni","sequence":"additional","affiliation":[{"name":"Division of Hemato\u2010oncology and Nephrology Department of Paediatrics University Hospital of Kinshasa School of Medicine University of Kinshasa Kinshasa Democratic Republic of Congo"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oscar N.","family":"Luboya","sequence":"additional","affiliation":[{"name":"Department of Pediatrics University Hospital of Lubumbashi University of Lubumbashi Kinshasa the Democratic Republic of Congo"},{"name":"School of Public Health University of Lubumbashi Lubumbashi the Democratic Republic of Congo"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,2,15]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2013.08.181"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1179\/146532808X335624"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjh.12912"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.22259"},{"key":"e_1_2_8_6_1","first-page":"137","article-title":"Serum zinc, copper and magnesium in sickle cell disease at Ibadan, South western 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