{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,21]],"date-time":"2026-03-21T07:38:19Z","timestamp":1774078699625,"version":"3.50.1"},"reference-count":33,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2017,2,21]],"date-time":"2017-02-21T00:00:00Z","timestamp":1487635200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100011813","name":"Changchun University of Science and Technology","doi-asserted-by":"crossref","award":["XJJLG-2016-10"],"award-info":[{"award-number":["XJJLG-2016-10"]}],"id":[{"id":"10.13039\/501100011813","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Laboratory Analysis"],"published-print":{"date-parts":[[2018,1]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Vitamins A, D (Vitamin D2 and vitamin D3) and E, play an important role during pregnancy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Sera were collected from 1056 normal pregnant women, who were between 18 and 40\u00a0years old, at seven different hospitals in northeastern China. The levels of Vitamin A and E in the sera samples were detected using <jats:styled-content style=\"fixed-case\">HPLC<\/jats:styled-content> (High Performance Liquid Chromatography), and the level of vitamin D was measured by <jats:styled-content style=\"fixed-case\">LC<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">MS<\/jats:styled-content> (Liquid Chromatography\u2010Mass Spectrometry). Data were analyzed using <jats:styled-content style=\"fixed-case\">IBM<\/jats:styled-content> SPSS Statistics 21.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The mean levels of vitamin A, D and E in the 1056 sera samples were 0.39\u00a0mg\/L (0.38\u20100.39), 20.44\u00a0\u03bcg\/L (19.86\u201021.08) and 12.96\u00a0mg\/L (12.70\u201013.25), respectively. The levels of vitamin A, D, and E deficiency were 17.05%, 0.19%, and 56.44%, respectively. The levels of vitamin A, D, and E of those between age 21 and 31 among the 1056 pregnant women were similar. The correlation of vitamin E and D was significant at the .01 level (two\u2010tailed), and the correlation of vitamin A and age was significant at the .05 level (2\u2010tailed).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>According to our finding, the levels of vitamin A, D, and E in the sera of pregnant women in northeastern China were affected by where they live and their age. Vitamin D deficiency was very serious, vitamin A deficiency was common, while vitamin E seems to be sufficient.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jcla.22176","type":"journal-article","created":{"date-parts":[[2017,2,21]],"date-time":"2017-02-21T16:23:56Z","timestamp":1487694236000},"source":"Crossref","is-referenced-by-count":8,"title":["An investigation of the levels of vitamins A, D, and E in the serum of Chinese pregnant women"],"prefix":"10.1002","volume":"32","author":[{"given":"Yu\u2010juan","family":"Chen","sequence":"first","affiliation":[{"name":"School of Life Science and Technology Changchun University of Science and Technology  Changchun China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhan\u2010dong","family":"Li","sequence":"additional","affiliation":[{"name":"College of Biology and Food Engineering Jinlin Teachers Institute of Engineering and Technology  Changchun China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cui\u2010ying","family":"Mao","sequence":"additional","affiliation":[{"name":"Department of Cardiology China\u2010Japan Union Hospital Jinlin University  Changchun China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xu","family":"Kang","sequence":"additional","affiliation":[{"name":"GeneScience Pharmaceuticals Co., Ltd. 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