{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T03:38:11Z","timestamp":1760240291325,"version":"3.41.2"},"reference-count":23,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2017,3,17]],"date-time":"2017-03-17T00:00:00Z","timestamp":1489708800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Laboratory Analysis"],"published-print":{"date-parts":[[2018,1]]},"abstract":"<jats:sec><jats:title>Purpose<\/jats:title><jats:p>The aim of this study was to investigate the value of biochemical profile of cyst fluid and diffusion\u2010weighted imaging (<jats:styled-content style=\"fixed-case\">DWI<\/jats:styled-content>) in differentiating hepatic hydatid cysts (<jats:styled-content style=\"fixed-case\">HC<\/jats:styled-content>s) from liver simple cysts.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and methods<\/jats:title><jats:p>Forty\u2010six patients underwent <jats:styled-content style=\"fixed-case\">MR<\/jats:styled-content> imaging. Twenty\u2010nine patients had 29 hydatid cysts and 17 patients had liver simple cysts. Thirteen patients with hydatid cysts and seven patients with liver simple cysts were evaluated with cyst fluid biochemical analysis. The concentration of glucose, protein, calcium ion (Ca<jats:sup>2+<\/jats:sup>) electrolyte, macroscopic appearance, and parasitological sediment were evaluated in this study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In the respect of biochemical analysis cyst fluid, the concentration of glucose and calcium ion of <jats:styled-content style=\"fixed-case\">HC<\/jats:styled-content>s was significantly higher than that of the liver simple cysts. In the respect of <jats:styled-content style=\"fixed-case\">DWI<\/jats:styled-content>, in the <jats:italic>b<\/jats:italic> 1000\u00a0s\/mm<jats:sup>2<\/jats:sup> value in respect of mean application data center (ADC) values, there was a statistically significant difference between <jats:styled-content style=\"fixed-case\">HC<\/jats:styled-content>s group (the mean value was (2.50\u00b10.79)\u00d710<jats:sup>\u22123<\/jats:sup>\u00a0mm\/s<jats:sup>2<\/jats:sup>) and liver simple cysts group (the mean value was (2.92\u00b10.66)\u00d710<jats:sup>\u22123<\/jats:sup>\u00a0mm\/s<jats:sup>2<\/jats:sup>). However, no statistically significant results were obtained in the <jats:styled-content style=\"fixed-case\">ADC<\/jats:styled-content> measurements of <jats:italic>b<\/jats:italic> 500\u00a0s\/mm<jats:sup>2<\/jats:sup> between two groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The analysis of cyst fluid combined with the measurement of <jats:styled-content style=\"fixed-case\">ADC<\/jats:styled-content> values in the <jats:italic>b<\/jats:italic> 1000\u00a0s\/mm<jats:sup>2<\/jats:sup> value could be considered a promising parameter as an alternative to the differential diagnosis of hepatic hydatid cysts from liver simple cysts.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jcla.22192","type":"journal-article","created":{"date-parts":[[2017,3,17]],"date-time":"2017-03-17T08:42:37Z","timestamp":1489740157000},"source":"Crossref","is-referenced-by-count":6,"title":["The study of biochemical profile of cyst fluid and diffusion\u2010weighted magnetic resonance 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