{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T05:36:05Z","timestamp":1792733765640,"version":"4.5.0"},"reference-count":17,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2017,3,27]],"date-time":"2017-03-27T00:00:00Z","timestamp":1490572800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81301503"],"award-info":[{"award-number":["81301503"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81601406"],"award-info":[{"award-number":["81601406"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003009","name":"Science and Technology Development Fund","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003009","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007289","name":"Nanjing Medical University","doi-asserted-by":"publisher","award":["2014NJMU062"],"award-info":[{"award-number":["2014NJMU062"]}],"id":[{"id":"10.13039\/501100007289","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Laboratory Analysis"],"published-print":{"date-parts":[[2018,1]]},"abstract":"Background<\/jats:title>Previous studies indicated that both red blood cell distribution width (RDW<\/jats:styled-content>) and neutrophil to lymphocyte ratio (NLR<\/jats:styled-content>) were useful indices in assessing the disease activity of autoimmune diseases. However, the evidence for the association between RDW<\/jats:styled-content>, NLR<\/jats:styled-content> and dermatomyositis (DM<\/jats:styled-content>) and polymyositis (PM<\/jats:styled-content>) is limited. The aim of this study is to investigate the association between the disease activity of PM<\/jats:styled-content>\/DM<\/jats:styled-content> and both RDW<\/jats:styled-content> and NLR<\/jats:styled-content>.<\/jats:p><\/jats:sec>Methods<\/jats:title>Medical records of 114 PM<\/jats:styled-content>\/DM<\/jats:styled-content> patients and 114 healthy controls were retrospectively reviewed, and their RDW<\/jats:styled-content>, NLR<\/jats:styled-content> and myositis disease activity assessment visual analogue scale (MYOACT<\/jats:styled-content>) on admission were extracted. The correlations between RDW<\/jats:styled-content>, NLR<\/jats:styled-content> and MYOACT<\/jats:styled-content> were analyzed using the Spearman approach and multivariable model.<\/jats:p><\/jats:sec>Results<\/jats:title>PM<\/jats:styled-content>\/DM<\/jats:styled-content> patients had significantly higher RDW<\/jats:styled-content> and NLR<\/jats:styled-content>. Increased RDW<\/jats:styled-content> in PM<\/jats:styled-content>\/DM<\/jats:styled-content> patients was not completely attributed to decreased hemoglobin or therapeutic agents. Both RDW<\/jats:styled-content> and NLR<\/jats:styled-content> are independently and positively correlated MYOACT<\/jats:styled-content>.<\/jats:p><\/jats:sec>Conclusion<\/jats:title>Both RDW<\/jats:styled-content> and NLR<\/jats:styled-content> are useful indices in assessing the disease activity of PM<\/jats:styled-content>\/DM<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jcla.22209","type":"journal-article","created":{"date-parts":[[2017,3,27]],"date-time":"2017-03-27T10:43:19Z","timestamp":1490611399000},"source":"Crossref","is-referenced-by-count":31,"title":["Red blood cell distribution width and neutrophil to lymphocyte ratio are correlated with disease activity of dermatomyositis and polymyositis"],"prefix":"10.1002","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8556-1792","authenticated-orcid":false,"given":"Ming\u2010Zhu","family":"Gao","sequence":"first","affiliation":[{"name":"Department of Laboratory Medicine Wuxi Second People's Hospital of Nanjing Medical University Wuxi China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuan\u2010Lan","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine No.455 Hospital of the Chinese People's Liberation Army Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao\u2010Dan","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine Wuxi Second People's Hospital of Nanjing Medical University Wuxi China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiang\u2010Wei","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Rheumatology Wuxi Second People's Hospital of Nanjing Medical University Wuxi China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rong","family":"Ji","sequence":"additional","affiliation":[{"name":"Department of Rheumatology Wuxi Second People's Hospital of Nanjing Medical University Wuxi China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bing","family":"Gu","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine The Affiliated Hospital of Xuzhou Medical University Xuzhou Jiangsu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ai\u2010Yan","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine The Affiliated Hospital of Xuzhou Medical University Xuzhou Jiangsu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ting\u2010Ting","family":"Hao","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine The Affiliated Hospital of Xuzhou Medical University Xuzhou Jiangsu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhi\u2010Jun","family":"Han","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine Wuxi Second People's Hospital of Nanjing Medical University Wuxi China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tian\u2010Li","family":"Ren","sequence":"additional","affiliation":[{"name":"Department of Rheumatology Wuxi Second People's Hospital of Nanjing Medical University Wuxi China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,3,27]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1515\/cclm-2015-0179"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.21037\/atm.2016.06.35"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.21037\/atm.2016.03.42"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000003430"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.21037\/atm.2016.10.50"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinbiochem.2014.08.022"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.21037\/jlpm.2016.10.02"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1155\/2016\/8191254"},{"key":"e_1_2_6_10_1","first-page":"50","article-title":"Prognostic value of neutrophil to lymphocyte ratio for gastric cancer","volume":"3","author":"Hu ZD","year":"2015","journal-title":"Ann Transl Med"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cca.2013.08.007"},{"key":"e_1_2_6_12_1","doi-asserted-by":"crossref","first-page":"505","DOI":"10.5858\/134.4.505.c","article-title":"Relation between red blood cell distribution width and inflammatory biomarkers in rheumatoid arthritis","volume":"134","author":"Lee WS","year":"2010","journal-title":"Arch Pathol Lab Med"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.7754\/Clin.Lab.2015.150941"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/ijlh.12460"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197502132920706"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/keg427"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.3109\/10408363.2014.992064"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1515\/cclm-2012-0704"}],"container-title":["Journal of Clinical Laboratory Analysis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjcla.22209","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jcla.22209","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,17]],"date-time":"2023-09-17T09:06:30Z","timestamp":1694941590000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jcla.22209"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,3,27]]},"references-count":17,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2018,1]]}},"alternative-id":["10.1002\/jcla.22209"],"URL":"https:\/\/doi.org\/10.1002\/jcla.22209","archive":["Portico"],"relation":{},"ISSN":["0887-8013","1098-2825"],"issn-type":[{"value":"0887-8013","type":"print"},{"value":"1098-2825","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,3,27]]},"article-number":"e22209"}}