{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T21:14:08Z","timestamp":1791666848813,"version":"4.3.4"},"reference-count":43,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2018,3,31]],"date-time":"2018-03-31T00:00:00Z","timestamp":1522454400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Laboratory Analysis"],"published-print":{"date-parts":[[2018,9]]},"abstract":"\n Background<\/jats:title>\n \n Acute kidney injury (\n AKI<\/jats:styled-content>\n ) is a common morbidity in neonatal intensive care units and associated with poor outcome. This study aimed to determine the prevalence of\n AKI<\/jats:styled-content>\n and provide a demographic data and risk factors associated with the mortality and morbidity.\n <\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n This is a retrospective study included 105 premature babies. Diagnosis of\n AKI<\/jats:styled-content>\n was based on neonatal\n KDIGO<\/jats:styled-content>\n classification criteria. The babies were stratified into two groups according to\n AKI<\/jats:styled-content>\n status during the hospitalization. Clinical and laboratory characteristics of the\n AKI<\/jats:styled-content>\n group were compared to non\u2010\n AKI<\/jats:styled-content>\n group.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n AKI<\/jats:styled-content>\n occurred in 21 (20.0%) of 105 premature babies, and mortality rate in these babies was 61.9%. Lower gestational weeks, lower Apgar scores at 5\u00a0minutes, lower systolic blood pressures, and inotropic supports were independent risk factors for the development of\n AKI<\/jats:styled-content>\n in preterm babies (\n P<\/jats:italic>\n \u00a0<\u00a0.05, for each). Oliguria, preeclampsia\/eclampsia, resuscitation at birth, lower diastolic blood pressure, patent ductus arteriosus (\n PDA<\/jats:styled-content>\n ), inotropic support, and furosemide treatment were associated with the mortality (\n P<\/jats:italic>\n \u00a0<\u00a0.05, for each).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n \n Prenatal risk factors and medical interventions are associated with\n AKI<\/jats:styled-content>\n , and\n AKI<\/jats:styled-content>\n is associated with increased morbidity and mortality. Therefore, identification of\n AKI<\/jats:styled-content>\n is very important in this vulnerable population and it should be performed as quickly as possible in all babies who are at high risk for developing of\n AKI<\/jats:styled-content>\n .\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1002\/jcla.22441","type":"journal-article","created":{"date-parts":[[2018,3,31]],"date-time":"2018-03-31T11:11:51Z","timestamp":1522494711000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":28,"title":["Risk factors and mortality rate in premature babies with acute kidney injury"],"prefix":"10.1002","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9749-6115","authenticated-orcid":false,"given":"Ahmet Taner","family":"Elmas","sequence":"first","affiliation":[{"name":"Department of Pediatric Nephrology Faculty of Medicine University of \u0130n\u00f6n\u00fc Malatya 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