{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,3]],"date-time":"2026-04-03T06:27:02Z","timestamp":1775197622844,"version":"3.50.1"},"reference-count":40,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2018,8,13]],"date-time":"2018-08-13T00:00:00Z","timestamp":1534118400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Laboratory Analysis"],"published-print":{"date-parts":[[2019,1]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>This study aimed to investigate the relationship between plasma D\u2010dimer level, preoperative complications, and thrombosis in liver transplant recipients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The clinical data of 525 liver transplant recipients with end\u2010stage liver disease (<jats:styled-content style=\"fixed-case\">ESLD<\/jats:styled-content>) in the First Affiliated Hospital of Zhejiang University from October 2012 to December 2015 were retrospectively analyzed. The patients were grouped based on thrombosis before and after surgery to determine the risk factors for postoperative thrombosis recurrence.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of the preoperative complications assessed, esophageal varices and thrombosis were significantly correlated (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.000); ascites, spontaneous bacterial peritonitis, and hepatic encephalopathy were significantly correlated with preoperative D\u2010dimer level (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001, <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001, and <jats:italic>P<\/jats:italic>\u00a0=\u00a00.002, respectively); during the first week after surgery, the D\u2010dimer level was significantly and consecutively higher than that before surgery and was significantly higher in the group with both preoperative and postoperative thrombosis than in the other groups on the first day after surgery (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001); the area under the curve (<jats:styled-content style=\"fixed-case\">AUC<\/jats:styled-content>) for diagnosis of postoperative thrombosis recurrence in the preoperative thrombosis group using plasma D\u2010dimer level on the first day after surgery was 0.698 (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.001); Cox regression analysis showed that D\u2010dimer was an independent risk factor for postoperative thrombosis recurrence (<jats:styled-content style=\"fixed-case\">HR<\/jats:styled-content>\u00a0=\u00a03.062, <jats:italic>P<\/jats:italic>\u00a0=\u00a00.029).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>D\u2010dimer level on the first day after liver transplant is related to thrombosis recurrence and is an independent risk factor for postoperative thrombosis recurrence.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jcla.22646","type":"journal-article","created":{"date-parts":[[2018,8,14]],"date-time":"2018-08-14T02:00:24Z","timestamp":1534212024000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["D\u2010dimer level in liver transplant recipients on the first day after surgery is correlated with postoperative thrombosis recurrence"],"prefix":"10.1002","volume":"33","author":[{"given":"Qun","family":"Zhang","sequence":"first","affiliation":[{"name":"Department of Laboratory Medicine First Affiliated Hospital College of Medicine Zhejiang University Hangzhou China"},{"name":"Department of Laboratory Medicine Tonglu First People's Hospital Hangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Renyong","family":"Guo","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine First Affiliated Hospital College of Medicine Zhejiang 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