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Significant variables chosen by multivariable logistic regression analysis were allocated the integral scores in proportion to its odds ratio (OR), and then the risk of decreased GFR was assessed based on the scores.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The people with abnormal homocysteine (Hcy) level (OR: 1.534, 95% confidential interval [CI]: 1.075\u20102.190,\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u00a0.018), males (OR: 2.054, 95%CI: 1.365\u20103.092,\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0&lt;\u00a0.001), and those at the age of 46\u201052\u00a0years (OR: 2.943, 95%CI: 1.546\u20105.605,\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u00a0.001), 52\u201059\u00a0years (OR: 3.664, 95%CI: 1.937\u20106.931,\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0&lt;\u00a0.001) and \u226559\u00a0years (OR: 13.452, 95%CI: 7.339\u201024.657,\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0&lt;\u00a0.001) were subjected to GFR reduction. These three variables were allocated the integral scores in proportion to its OR, and four risk categories were divided according to the scores. The prevalence of the decreased GFR in people with low (score 0\u20104, n\u00a0=\u00a08), below the average (score 4\u20106, n\u00a0=\u00a037), above the average (score 6\u201013, n\u00a0=\u00a047), and high risks (score\u00a0\u2265\u00a013, n\u00a0=\u00a0103) was 5.26%, 16.89%, 22.93% and 50.24%, respectively, and this prevalence raised with the increase of scores (\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0&lt;\u00a0.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>A risk scoring system is developed in this study, which may offer a specific risk stratification for GFR reduction in Chinese general population.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/jcla.23143","type":"journal-article","created":{"date-parts":[[2019,12,23]],"date-time":"2019-12-23T01:44:15Z","timestamp":1577065455000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["A risk scoring system for the decreased glomerular filtration rate in Chinese general population"],"prefix":"10.1002","volume":"34","author":[{"given":"Yan","family":"Gu","sequence":"first","affiliation":[{"name":"Division of Nephrology, Department of Geriatrics The First Affiliated Hospital of Nanjing Medical University Nanjing China"},{"name":"Department of Geriatrics The Second Affiliated Hospital of Nantong University Nantong China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Min","family":"Chen","sequence":"additional","affiliation":[{"name":"Division of Nephrology, Department of Geriatrics The First Affiliated Hospital of Nanjing Medical University Nanjing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bei","family":"Zhu","sequence":"additional","affiliation":[{"name":"Division of Nephrology, Department of Geriatrics The First Affiliated Hospital of Nanjing Medical University Nanjing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaohua","family":"Pei","sequence":"additional","affiliation":[{"name":"Division of Nephrology, Department of Geriatrics The First Affiliated Hospital of Nanjing Medical University Nanjing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhenzhu","family":"Yong","sequence":"additional","affiliation":[{"name":"Division of Nephrology, Department of Geriatrics The First Affiliated Hospital of Nanjing Medical University Nanjing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaona","family":"Li","sequence":"additional","affiliation":[{"name":"Health Management Center The First Affiliated Hospital of Nanjing Medical University Nanjing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qun","family":"Zhang","sequence":"additional","affiliation":[{"name":"Health Management Center The First Affiliated Hospital of Nanjing Medical University Nanjing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8211-2900","authenticated-orcid":false,"given":"Weihong","family":"Zhao","sequence":"additional","affiliation":[{"name":"Division of Nephrology, Department of Geriatrics The First Affiliated Hospital of Nanjing Medical University Nanjing China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,12,22]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(10)60674-5"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/ki.2010.550"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2214-109X(16)00071-1"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(12)60033-6"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-139-2-200307150-00013"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.7326\/AITC201506020"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(13)60687-X"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/cpt.729"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1159\/000455197"},{"issue":"6","key":"e_1_2_6_11_1","first-page":"1091","article-title":"Clinical practice guidelines for chronic kidney disease in adults: part II. 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