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In general, myositis\u2010specific autoantibodies (MSAs) and myositis\u2010associated autoantibodies (MAAs) have been shown to be useful biomarkers for its diagnosis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>In the present study, focus was given in assessing the presence, prevalence, and diagnostic values of myositis autoantibodies in Chinese patients diagnosed with CAM. The sera collected from 49 CAM patients, 108 dermatomyositis\/polymyositis (DM\/PM) patients without cancer, 105 disease controls, and 60 healthy controls were detected for the presence of 16 autoantigens (Jo\u20101, OJ, EJ, PL\u20107, PL\u201012, MDA5, TIF1\u03b3, Mi\u20102\u03b1, Mi\u20102\u03b2, SAE1, NXP2, SRP, Ku, PM\u2010Scl75, PM\u2010Scl100, and Ro\u201052) using a commercial Euroline assay.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The frequency of anti\u2010TIF1\u03b3 was significantly higher in CAM patients than in DM\/PM patients without cancer (46.9% vs 14.8%,\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0&lt;\u00a0.001). Importantly, the sensitivity and specificity for this MSA were 46.9% and 85.2%, respectively. These helped to differentiate CAM patients from DM\/PM patients without cancer. However, there was no difference in other MSAs and MAAs between CAM and DM\/PM patients without cancer.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The present study indicates that anti\u2010TIF1\u03b3 levels can serve as important biomarkers for CAM diagnosis and help in distinguishing between CAM and DM\/PM patients without cancer.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/jcla.23307","type":"journal-article","created":{"date-parts":[[2020,3,27]],"date-time":"2020-03-27T23:41:41Z","timestamp":1585352501000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Analysis of myositis autoantibodies in Chinese patients with cancer\u2010associated 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Peking Union Medical College Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chanyuan","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Rheumatology and Clinical Immunology Peking Union Medical College Hospital Key Laboratory of Rheumatology and Clinical Immunology Ministry of Education Chinese Academy of Medical Sciences and Peking Union Medical College Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanfang","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Clinical Laboratory Peking Union Medical College Hospital Peking Union Medical College and Chinese Academy of Medical Sciences Beijing China"},{"name":"Department of Medical Laboratory the First Hospital of Jilin University Changchun China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linlin","family":"Cheng","sequence":"additional","affiliation":[{"name":"Department of Clinical Laboratory Peking 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