{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,27]],"date-time":"2026-01-27T08:23:55Z","timestamp":1769502235753,"version":"3.49.0"},"reference-count":16,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2021,3,5]],"date-time":"2021-03-05T00:00:00Z","timestamp":1614902400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Laboratory Analysis"],"published-print":{"date-parts":[[2021,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>SARS\u2010CoV\u20102\u00a0has become a global pandemic due to its capacity for rapid transmission. In this context, an early and rapid diagnosis of infected patients that do not require expensive equipment or highly trained personnel is crucial in order to reduce the contagious rate. The aim of this study was to evaluate a chromatographic immunoassay's performance for the rapid diagnosis of SARS\u2010CoV\u2010antigen.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A cross\u2010sectional study included 369 adults from Western M\u00e9xico with diagnosis or suspicion of SARS\u2010CoV\u20102 infection. Two samples were collected; a naso\u2010oropharyngeal was used for a molecular determination of SARS\u2010CoV\u20102 RNA. The molecular analysis was carried out using DeCoV19 Kit Triplex (Genes2life S.A.P.I.) based on the CDC diagnostic panel for N1, N2, and N3 regions. The second sample was retrieved from a nasopharyngeal rub and used for the rapid diagnosis of SARS\u2010CoV\u20102 antigen employing the commercial STANDARD\u2122 Q COVID\u201019 Ag Test (SD BIOSENSOR).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Overall, in 28.2% of the patients was detected the SARS\u2010CoV\u20102 RNA, and 21.4% were positive for antigen detection. The rapid antigen test showed a sensitivity and specificity of 75.9% and 100%, respectively, with a positive predictive and negative values of 100% and 91%. Symptoms as anosmia presented a high OR for the positive diagnosis for both test, reverse transcription\u2010polymerase chain reaction (RT\u2010PCR), and the rapid antigen test of 8.86 (CI\u00a0=\u00a04.91\u201316) and 6.09 (CI\u00a0=\u00a03.42\u201310.85), respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>SD BIOSENSOR is a useful assay, but some caveats must be considered before the general implementation.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jcla.23745","type":"journal-article","created":{"date-parts":[[2021,3,6]],"date-time":"2021-03-06T07:11:49Z","timestamp":1615014709000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Performance evaluation of a lateral flow assay for nasopharyngeal antigen detection for SARS\u2010CoV\u20102 diagnosis"],"prefix":"10.1002","volume":"35","author":[{"given":"Marcela","family":"Pe\u00f1a\u2010Rodr\u00edguez","sequence":"first","affiliation":[{"name":"Centro Universitario de Ciencias de la Salud Universidad de Guadalajara Guadalajara M\u00e9xico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Oliver","family":"Viera\u2010Segura","sequence":"additional","affiliation":[{"name":"Laboratorio de Enfermedades Emergentes y Reemergentes Departamento de Microbiolog\u00eda y Patolog\u00eda Centro Universitario de Ciencias de la Salud Universidad de Guadalajara Guadalajara Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mariel","family":"Garc\u00eda\u2010Chagoll\u00e1n","sequence":"additional","affiliation":[{"name":"Departamento de Cl\u00ednicas M\u00e9dicas Centro Universitario de Ciencias de la Salud Instituto de Investigaci\u00f3n en Ciencias Biom\u00e9dicas Universidad de Guadalajara Guadalajara M\u00e9xico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9 Sergio","family":"Zepeda\u2010Nu\u00f1o","sequence":"additional","affiliation":[{"name":"Departamento de Microbiolog\u00eda y Patolog\u00eda, Centro de Investigaci\u00f3n y Diagn\u00f3stico de Patolog\u00eda Centro Universitario de Ciencias de la Salud Universidad de Guadalajara Guadalajara M\u00e9xico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2272-9260","authenticated-orcid":false,"given":"Jos\u00e9 Francisco","family":"Mu\u00f1oz\u2010Valle","sequence":"additional","affiliation":[{"name":"Departamento de Cl\u00ednicas M\u00e9dicas Centro Universitario de Ciencias de la Salud Instituto de Investigaci\u00f3n en Ciencias Biom\u00e9dicas Universidad de Guadalajara Guadalajara M\u00e9xico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jes\u00fas","family":"Mora\u2010Mora","sequence":"additional","affiliation":[{"name":"Laboratorio de Enfermedades Emergentes y Reemergentes Departamento de Microbiolog\u00eda y Patolog\u00eda Centro Universitario de Ciencias de la Salud Universidad de Guadalajara Guadalajara Mexico"},{"name":"Maestr\u00eda en Ciencias M\u00e9dicas Universidad de Colima Colima M\u00e9xico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabriela","family":"Espinoza\u2010De Le\u00f3n","sequence":"additional","affiliation":[{"name":"Laboratorio de Enfermedades Emergentes y Reemergentes Departamento de Microbiolog\u00eda y Patolog\u00eda Centro Universitario de Ciencias de la Salud Universidad de Guadalajara Guadalajara Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gustavo","family":"Bustillo\u2010Armend\u00e1riz","sequence":"additional","affiliation":[{"name":"Bustar SAPI de CV Zapopan Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fernanda","family":"Garc\u00eda\u2010Cedillo","sequence":"additional","affiliation":[{"name":"Bustar SAPI de CV Zapopan Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4749-2498","authenticated-orcid":false,"given":"Natali","family":"Vega\u2010Maga\u00f1a","sequence":"additional","affiliation":[{"name":"Laboratorio de Enfermedades Emergentes y Reemergentes Departamento de Microbiolog\u00eda y Patolog\u00eda Centro Universitario de Ciencias de la Salud Universidad de Guadalajara Guadalajara Mexico"},{"name":"Departamento de Cl\u00ednicas M\u00e9dicas Centro Universitario de Ciencias de la Salud Instituto de Investigaci\u00f3n en Ciencias Biom\u00e9dicas Universidad de Guadalajara Guadalajara M\u00e9xico"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,3,5]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-020-2012-7"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2002032"},{"key":"e_1_2_8_4_1","unstructured":"Johns Hopkins University.COVID\u201019 Map. Johns Hopkins Coronavirus Resource Center. [cited November 30 2020]. 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