{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,20]],"date-time":"2026-04-20T10:52:35Z","timestamp":1776682355421,"version":"3.51.2"},"reference-count":25,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2022,7,6]],"date-time":"2022-07-06T00:00:00Z","timestamp":1657065600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Laboratory Analysis"],"published-print":{"date-parts":[[2022,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Mucormycosis is a rare invasive fungal disease with high mortality. Early diagnosis and targeted drugs are crucial to improving clinical outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We searched the electronic hospital database of the First Affiliated Hospital of Zhejiang University School of Medicine for adult patients with mucormycosis between 2000 and 2021. Demographic, clinical, treatment, and outcome data were collected and compared with the data in the relevant literature.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Eleven cases of mucormycosis\u2014four of multisite infection, one of skin infection, five of lung infection, and one of gastrointestinal infection\u2014were found and analyzed. The patients were diagnosed mainly based on pathological and histological findings, and three patients had metagenomic next\u2010generation sequencing findings. Delayed diagnosis (i.e., diagnosis &gt;7\u2009days after patient admission or &gt;30\u2009days after onset of symptoms) results in poor prognosis compared with early diagnosis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Improving awareness and shortening diagnosis time may improve the prognosis of mucormycosis. If mucormycosis is suspected, appropriate samples should be collected as soon as possible and submitted for biopsy, culture, or mNGS to confirm the diagnosis.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jcla.24588","type":"journal-article","created":{"date-parts":[[2022,7,6]],"date-time":"2022-07-06T11:32:09Z","timestamp":1657107129000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Multiple diagnostic methods for mucormycosis: A retrospective case series"],"prefix":"10.1002","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9062-3097","authenticated-orcid":false,"given":"JiaXin","family":"Wang","sequence":"first","affiliation":[{"name":"Kidney Disease Center, The First Affiliated Hospital, College of Medicine Zhejiang University  Hangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"YaoMin","family":"Wang","sequence":"additional","affiliation":[{"name":"Kidney Disease Center, 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