{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T13:18:36Z","timestamp":1770729516523,"version":"3.49.0"},"reference-count":21,"publisher":"Wiley","issue":"19-20","license":[{"start":{"date-parts":[[2023,10,6]],"date-time":"2023-10-06T00:00:00Z","timestamp":1696550400000},"content-version":"vor","delay-in-days":5,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Laboratory Analysis"],"published-print":{"date-parts":[[2023,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p><jats:italic>Candida<\/jats:italic> pericardial infection is a rare clinical entity usually related to recent cardiothoracic surgery and chronic debilitating conditions. During the COVID\u201019 pandemic, invasive fungal infections have been on the rise, likely due to a combination of factors such as immunosuppression, underlying conditions like diabetes, and surgical procedures.<\/jats:p><\/jats:sec><jats:sec><jats:title>Case Presentation<\/jats:title><jats:p>Herein, we report a 67\u2010year\u2010old diabetic woman with a history of COVID\u201019 infection who received a high dose of corticosteroids a few months before admission, and previous myocardial infarction for more than 12\u2009years. The patient had a positive cardiac tamponade with signs of dyspnea, chest pain, and low blood pressure. Echocardiographic data were more in favor of constrictive pericarditis. The patient underwent urgent echocardiography\u2010guided pericardiocentesis and then broad\u2010spectrum antibiotic treatment was prescribed. Repeated\u00a0echocardiography implied a persistent pericardial effusion 10\u2009days later. Subxiphoid aspirates and biopsied tissues showed budding yeast cells and yeast colonies grew on culture media identified as <jats:italic>Candida albicans<\/jats:italic>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This report should bring to the attention of physicians toward the possibility of <jats:italic>Candida<\/jats:italic> pericardial infection presenting with cardiac tamponade after COVID\u201019 infection and cardiothoracic surgery. Echocardiographic assessment, prompt pericardiotomy, molecular\u2010based identification of causative agent, and early administration of appropriate antifungal treatment should improve the patient's survival.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jcla.24968","type":"journal-article","created":{"date-parts":[[2023,10,8]],"date-time":"2023-10-08T18:30:03Z","timestamp":1696789803000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["A fatal <i>Candida albicans<\/i> pericarditis presenting with cardiac tamponade after <scp>COVID<\/scp>\u201019 infection and cardiothoracic surgery"],"prefix":"10.1002","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5808-6412","authenticated-orcid":false,"given":"Maryam","family":"Salimi","sequence":"first","affiliation":[{"name":"Student Research Committee Mazandaran University of Medical Sciences  Sari Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7298-7789","authenticated-orcid":false,"given":"Lotfollah","family":"Davoodi","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases, Antimicrobial Resistance Research Center, Communicable Diseases Institute Mazandaran University of Medical Sciences  Sari Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rozita","family":"Jalalian","sequence":"additional","affiliation":[{"name":"Department of Cardiology, School of Medicine, Cardiovascular Research Center Mazandaran University of Medical Sciences  Sari Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masood","family":"Darayee","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, School of Medicine, Cardiovascular Research Center Mazandaran University of Medical Sciences  Sari 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