{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,23]],"date-time":"2026-04-23T00:11:13Z","timestamp":1776903073028,"version":"3.51.2"},"reference-count":32,"publisher":"Wiley","issue":"22","license":[{"start":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T00:00:00Z","timestamp":1759968000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2016YFC1305700"],"award-info":[{"award-number":["2016YFC1305700"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Laboratory Analysis"],"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The prevalence of diabetes prevalence has surged in China, becoming a severe public health issue. However, data on abnormal glucose metabolism among ethnic minorities, particularly the Zhuang population, remains limited. This study aims to fill this gap by analyzing the prevalence and risk factors of glucose abnormalities in the Zhuang population.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>In 2017, data were gathered from a sample of 1957 Zhuang adults, aged 18 and older, who underwent a comprehensive physical examination at the First Affiliated Hospital of Guangxi Medical University. Variables included demographic information, lifestyle habits, anthropometric measurements, and biochemical indicators. Abnormal glucose metabolism was diagnosed based on fasting blood glucose (GLU) and 2\u2010h postprandial glucose (2hPG) levels. Statistical analysis was performed using SPSS 24.0.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>This study shows reveals a 37.52% prevalence of abnormal glucose metabolism among the Zhuang population in Nanning, with Type 2 diabetes mellitus (T2DM) and pre\u2010diabetes (PDM) rates of 9.7% and 23.17%, respectively. Risk factors identified include age, high BMI, hypertension, dyslipidemia, and alcohol consumption.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This study highlights that the prevalence of abnormal glucose metabolism is very high in Nanning, Guangxi. Targeted intervention measures, such as enhanced health education, should be implemented for high\u2010risk populations to effectively implement diabetes prevention policies and interventions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Trial Registration<\/jats:title>\n                    <jats:p>This study is not a clinical trial, so there is no clinical trial registry<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/jcla.70117","type":"journal-article","created":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T12:35:17Z","timestamp":1760013317000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["The Prevalence of Abnormal Glucose Metabolism and Its Correlates in the Zhuang Nationality, Nanning, Guangxi Province"],"prefix":"10.1002","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-9720-4353","authenticated-orcid":false,"given":"Qin","family":"Yuanyuan","sequence":"first","affiliation":[{"name":"Key Laboratory of Clinical Laboratory Medicine of Guangxi Department of Education, Department of Clinical Laboratory The First Affiliated Hospital of Guangxi Medical University  Nanning China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3492-321X","authenticated-orcid":false,"given":"Liao","family":"Lin","sequence":"additional","affiliation":[{"name":"Key Laboratory of Clinical Laboratory Medicine of Guangxi Department of Education, Department of Clinical Laboratory The First Affiliated Hospital of Guangxi Medical University  Nanning China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chen","family":"Qingyun","sequence":"additional","affiliation":[{"name":"Health Management Department The First Affiliated Hospital of Guangxi Medical University  Nanning China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huang","family":"Yunhua","sequence":"additional","affiliation":[{"name":"Key Laboratory of Clinical Laboratory Medicine of Guangxi Department of Education, Department of Clinical Laboratory The First Affiliated Hospital of Guangxi Medical University  Nanning China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4539-6278","authenticated-orcid":false,"given":"Lin","family":"Faquan","sequence":"additional","affiliation":[{"name":"Key Laboratory of Clinical Laboratory Medicine of Guangxi Department of Education, Department of Clinical Laboratory The First Affiliated Hospital of Guangxi Medical University  Nanning China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,10,9]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.diabres.2019.107843"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2023.4063"},{"issue":"1","key":"e_1_2_11_4_1","first-page":"34","article-title":"Comparative Prognostic Performance of Definitions of Prediabetes: A Prospective Cohort Analysis of the Atherosclerosis Risk in Communities (ARIC) Study","volume":"5","author":"Warren B.","year":"2016","journal-title":"Endocrinology"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00125-021-05592-3"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ecl.2017.10.002"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/s42255-024-01190-w"},{"issue":"3","key":"e_1_2_11_8_1","first-page":"140","article-title":"Meta\u2010Analysis of Smoking Prevalence in Iran","volume":"5","author":"Moosazadeh M.","year":"2013","journal-title":"Addiction & Health"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcla.24711"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.lanwpc.2023.100700"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.diabet.2018.08.008"},{"issue":"4","key":"e_1_2_11_12_1","first-page":"250","article-title":"The Investigation of the Morbidity, Awareness Rate, Treatment Rate and Control Rate of Diabetes Among Adult Residents in Guangxi","volume":"26","author":"weijiang L.","year":"2018","journal-title":"Chinese Journal of Prevention and Control of Chronic Diseases"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/CM9.0000000000003207"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2017.7596"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.m997"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.diabres.2021.109119"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/1753-0407.13492"},{"issue":"18","key":"e_1_2_11_18_1","first-page":"3029","article-title":"Research Progress on the Relationship Between Androgens, Diabetes, and Insulin Resistance","volume":"27","author":"Shen jie Y. d.","year":"2016","journal-title":"Hainan Medical Journal"},{"issue":"3","key":"e_1_2_11_19_1","article-title":"The Prevalence of Diabetes and Prediabetes: A Population\u2010Based Study","volume":"133","author":"Zieleniewska N. A.","year":"2023","journal-title":"Polish Archives of Internal Medicine"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1093\/ageing\/afad128"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdi.13763"},{"issue":"24","key":"e_1_2_11_22_1","first-page":"8","article-title":"Genetic Polymorphism of 31 SNPs in PPARG Gene and Their Correlation With Type 2 Diabetes in Kirgiz Population","volume":"33","author":"Ruzi Z.","year":"2015","journal-title":"Science & Technology Review"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ebiom.2015.09.004"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu10081011"},{"issue":"12","key":"e_1_2_11_25_1","first-page":"1421","article-title":"Prospective Cohort Study on the Association of Body Mass Index Level and Its Dynamic Changes on Risks of Incident Comorbidity Among Hypertension,Diabetes and Dyslipidemia","volume":"27","author":"Zhou j.","year":"2023","journal-title":"Chinese Journal of Disease Control and Prevention"},{"key":"e_1_2_11_26_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12944-016-0328-y"},{"key":"e_1_2_11_27_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12933-022-01516-6"},{"key":"e_1_2_11_28_1","doi-asserted-by":"publisher","DOI":"10.1111\/dom.15264"},{"issue":"20","key":"e_1_2_11_29_1","first-page":"41","article-title":"Investigation on the Detection Rate and Risk Factors of Dyslipidemia in the Physical Examination Population of the Zhuang Nationality in Nanning City","volume":"19","author":"Yunhua H.","year":"2022","journal-title":"China Medical Herald"},{"key":"e_1_2_11_30_1","doi-asserted-by":"publisher","DOI":"10.1080\/17512433.2017.1263565"},{"key":"e_1_2_11_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pcad.2019.07.006"},{"key":"e_1_2_11_32_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc14-1556"},{"issue":"27","key":"e_1_2_11_33_1","first-page":"4","article-title":"Study on the Dietary Habits and the Risk of Type 2 Diabetes Among Zhuang Z\u00fa Residents in Nanning City, Guangxi Zhuang Autonomous Region","volume":"17","author":"Zhong x.","year":"2020","journal-title":"China Medical Herald"}],"container-title":["Journal of Clinical Laboratory Analysis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jcla.70117","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,24]],"date-time":"2025-11-24T04:21:11Z","timestamp":1763958071000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jcla.70117"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10,9]]},"references-count":32,"journal-issue":{"issue":"22","published-print":{"date-parts":[[2025,11]]}},"alternative-id":["10.1002\/jcla.70117"],"URL":"https:\/\/doi.org\/10.1002\/jcla.70117","archive":["Portico"],"relation":{},"ISSN":["0887-8013","1098-2825"],"issn-type":[{"value":"0887-8013","type":"print"},{"value":"1098-2825","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,10,9]]},"assertion":[{"value":"2025-02-05","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-09-28","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-10-09","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70117"}}