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We investigated the effects of different presentations of major depression on mother\u2010infant emotional availability (EA).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Data were obtained from 115 mother\u2010infant dyads from a longitudinal pregnancy cohort. Disorders, symptoms, and antidepressant use were assessed in pregnancy and postpartum, and EA was observed 6\u2010month postpartum. Major Depressive Disorder (MDD) and Generalized Anxiety Disorder (GAD) were assessed using the Structured Clinical Interview for the DSM\u20105. A series of multivariate analyses of covariance analyses' examining the effects of disorder on EA were conducted.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>After controlling for maternal age, antidepressant use, and postpartum depressive symptoms, MDD accounted for 20% of the variance in EA. In the MDD\/GAD group, 93% of interactions were rated as emotionally unavailable, nearly threefold the comparison group rate.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Findings demonstrate that different presentations of major depression are associated with observed differences in mother\u2010infant EA.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jclp.23235","type":"journal-article","created":{"date-parts":[[2021,8,16]],"date-time":"2021-08-16T19:15:59Z","timestamp":1629141359000},"page":"570-589","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Major depression and generalised anxiety disorder: An analysis of the effects of remission status and comorbidity on mother\u2010infant emotional availability in the perinatal period"],"prefix":"10.1002","volume":"78","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5090-9736","authenticated-orcid":false,"given":"Pavitra","family":"Aran","sequence":"first","affiliation":[{"name":"Discipline of Psychology Murdoch University  Perth Western Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2519-7976","authenticated-orcid":false,"given":"Andrew","family":"Lewis","sequence":"additional","affiliation":[{"name":"Discipline of Psychology Murdoch University  Perth Western Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7228-3490","authenticated-orcid":false,"given":"Stuart","family":"Watson","sequence":"additional","affiliation":[{"name":"Discipline of Psychology Murdoch University  Perth Western Australia Australia"},{"name":"School of Medicine University of Notre Dame  Fremantle Western Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3909-1918","authenticated-orcid":false,"given":"Megan","family":"Galbally","sequence":"additional","affiliation":[{"name":"Discipline of Psychology Murdoch University  Perth Western Australia Australia"},{"name":"School of Medicine University of Notre Dame  Fremantle Western Australia Australia"},{"name":"Women's Health, Genetics and Mental Health King Edward Memorial Hospital  Subiaco Western Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,8,16]]},"reference":[{"key":"e_1_2_13_2_1","first-page":"1","article-title":"Emotional availability in women with bipolar disorder and major depression: A longitudinal pregnancy cohort study","author":"Aran P.","year":"2021","journal-title":"Australian & New Zealand Journal of Psychiatry"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.earlhumdev.2018.05.007"},{"key":"e_1_2_13_4_1","volume-title":"Mental health care in the perinatal period: Australian clinical practice guideline","author":"Austin M. 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